Targeting the tyrosine kinase signalling pathways for treatment of immune-mediated glomerulonephritis: from bench to bedside and beyond

Etiology and Outcome of Crescentic Glomerulonephritis From a Single Center in China: A 10-Year Review

(2016) Shasha Chen et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

Clinical Safety and Efficacy of Nilotinib or Dasatinib in Patients With Newly Diagnosed Chronic-Phase Chronic Myelogenous Leukemia and Pre-Existing Liver and/or Renal Dysfunction

(2016) Koji Sasaki et al.   Clinical Lymphoma Myeloma & Leukemia

Imatinib Increases Serum Creatinine by Inhibiting Its Tubular Secretion in a Reversible Fashion in Chronic Myeloid Leukemia

(2016) Emmanuelle Vidal-Petiot et al.   Clinical Lymphoma Myeloma & Leukemia

Protective effects of genetic inhibition of Discoidin Domain Receptor 1 in experimental renal disease

(2016) Monique Kerroch et al.   Scientific Reports

A Structural Perspective on the Regulation of the Epidermal Growth Factor Receptor

(2015) Erika Kovacs et al.   Annual Review of Biochemistry

Estimated glomerular filtration rate changes in patients with chronic myeloid leukemia treated with tyrosine kinase inhibitors

(2015) Musa Yilmaz et al.   CANCER

Receptor tyrosine kinase inhibitors: Are they real tumor killers?

(2015) Andreas K.A. Gaumann et al.   INTERNATIONAL JOURNAL OF CANCER

Targeting non-receptor tyrosine kinases using small molecule inhibitors: an overview of recent advances

(2015) Mohammad Hojjat-Farsangi   JOURNAL OF DRUG TARGETING

Epidermal growth factor receptor inhibition with erlotinib ameliorates anti-Thy 1.1-induced experimental glomerulonephritis

(2015) Jukka M. Rintala et al.   JOURNAL OF NEPHROLOGY

Myeloid cell-mediated renal injury in rapidly progressive glomerulonephritis depends upon spleen tyrosine kinase

(2015) Jessica Ryan et al.   JOURNAL OF PATHOLOGY

Correlation of disease activity in proliferative glomerulonephritis with glomerular spleen tyrosine kinase expression

(2015) Stephen P. McAdoo et al.   KIDNEY INTERNATIONAL

New developments in the genetics, pathogenesis, and therapy of IgA nephropathy

(2015) Riccardo Magistroni et al.   KIDNEY INTERNATIONAL

Global, regional, and national incidence, prevalence, and years lived with disability for 301 acute and chronic diseases and injuries in 188 countries, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013

(2015) Theo Vos et al.   LANCET

Discoidin domain receptor-1 and periostin: new players in chronic kidney disease

(2015) Carlo Alfieri et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Predictors of renal and patient outcomes in anti-GBM disease: clinicopathologic analysis of a two-centre cohort

(2015) B. Alchi et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Intensive Supportive Care plus Immunosuppression in IgA Nephropathy

(2015) Thomas Rauen et al.   NEW ENGLAND JOURNAL OF MEDICINE

FDA-approved small-molecule kinase inhibitors

(2015) Peng Wu et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

The Role of MicroRNAs and Human Epidermal Growth Factor Receptor 2 in Proliferative Lupus Nephritis

(2015) Patrícia Costa-Reis et al.   Arthritis & Rheumatology

Is Newer Safer? Adverse Events Associated with First-Line Therapies for ANCA-Associated Vasculitis and Lupus Nephritis

(2014) J. Hogan et al.   Clinical Journal of the American Society of Nephrology

Non-receptor protein tyrosine kinases signaling pathways in normal and cancer cells

(2014) Elzbieta Gocek et al.   CRITICAL REVIEWS IN CLINICAL LABORATORY SCIENCES

Spleen Tyrosine Kinase Inhibitors for Rheumatoid Arthritis: Where Are We Now?

(2014) Ian C. Scott et al.   DRUGS

Spleen Tyrosine Kinase Inhibition Attenuates Autoantibody Production and Reverses Experimental Autoimmune GN

(2014) S. P. McAdoo et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

SYK inhibition in experimental autoimmune vasculitis and its glomerular expression in ANCA-associated vasculitis

(2014) Stephen P McAdoo et al.   LANCET

Long-term outcome of anti-neutrophil cytoplasm antibody-associated glomerulonephritis: evaluation of the international histological classification and other prognostic factors

(2014) Anisha Tanna et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Elevated Soluble VEGF Receptor sFlt-1 Correlates with Endothelial Injury in IgA Nephropathy

(2014) Ya-Ling Zhai et al.   PLoS One

Dasatinib-Induced Nephrotic-Range Proteinuria

(2013) Eric Wallace et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

Safety profile of protein kinase inhibitors in rheumatoid arthritis: systematic review and meta-analysis

(2013) Eva Salgado et al.   ANNALS OF THE RHEUMATIC DISEASES

Suppression of Glomerulonephritis in Lupus-Prone NZB × NZW Mice by RN486, a Selective Inhibitor of Bruton's Tyrosine Kinase

(2013) Paola Mina-Osorio et al.   ARTHRITIS AND RHEUMATISM

The contribution of VEGF signalling to fostamatinib-induced blood pressure elevation

(2013) M Skinner et al.   BRITISH JOURNAL OF PHARMACOLOGY

Selective Inhibition of BTK Prevents Murine Lupus and Antibody-Mediated Glomerulonephritis

(2013) A. L. Rankin et al.   JOURNAL OF IMMUNOLOGY

Brutonˈs tyrosine kinase-an integral protein of B cell development that also has an essential role in the innate immune system

(2013) Gabriela López-Herrera et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Imatinib: Novel Treatment of Immune-Mediated Kidney Injury

(2013) E. Wallace et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Role of epidermal growth factor receptor in acute and chronic kidney injury

(2013) Jinhua Tang et al.   KIDNEY INTERNATIONAL

Animal models of chronic kidney disease: useful but not perfect

(2013) G. J. Becker et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Genetic inhibition of discoidin domain receptor 1 protects mice against crescentic glomerulonephritis

(2012) Monique Kerroch et al.   FASEB JOURNAL

Spleen Tyrosine Kinase Is Important in the Production of Proinflammatory Cytokines and Cell Proliferation in Human Mesangial Cells following Stimulation with IgA1 Isolated from IgA Nephropathy Patients

(2012) M. J. Kim et al.   JOURNAL OF IMMUNOLOGY

Basic and Translational Concepts of Immune-Mediated Glomerular Diseases

(2012) W. G. Couser   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Long- and short-term treatment with imatinib attenuates the development of chronic kidney disease in experimental anti-glomerular basement membrane nephritis

(2012) Masayuki Iyoda et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Epidermal growth factor: a new therapeutic target in glomerular disease

(2012) M. Flamant et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Modulating proximal cell signaling by targeting Btk ameliorates humoral autoimmunity and end-organ disease in murine lupus

(2012) Jack Hutcheson et al.   ARTHRITIS RESEARCH & THERAPY

Imatinib Therapy for Non–Infection-Related Type II Cryoglobulinemia With Membranoproliferative Glomerulonephritis

(2011) Eric Wallace et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

Animal models of antineutrophil cytoplasm antibody-associated vasculitis

(2011) Alan D. Salama et al.   CURRENT OPINION IN RHEUMATOLOGY

Depletion of Autoreactive Plasma Cells and Treatment of Lupus Nephritis in Mice Using CEP-33779, a Novel, Orally Active, Selective Inhibitor of JAK2

(2011) L. D. Lu et al.   JOURNAL OF IMMUNOLOGY

Elevated Soluble Flt1 Inhibits Endothelial Repair in PR3-ANCA-Associated Vasculitis

(2011) S. Le Roux et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Epidermal growth factor receptor promotes glomerular injury and renal failure in rapidly progressive crescentic glomerulonephritis

(2011) Guillaume Bollée et al.   NATURE MEDICINE

Effects of p38 mitogen-activated protein kinase inhibition on anti-neutrophil cytoplasmic autoantibody pathogenicity in vitro and in vivo

(2010) B. S. van der Veen et al.   ANNALS OF THE RHEUMATIC DISEASES

Focal segmental glomerulosclerosis plays a major role in the progression of IgA nephropathy. I. Immunohistochemical studies

(2010) Gary S. Hill et al.   KIDNEY INTERNATIONAL

Jak/STAT signaling is involved in the inflammatory infiltration of the kidneys in MRL/lpr mice

(2010) S. Wang et al.   LUPUS

Targeting non-malignant disorders with tyrosine kinase inhibitors

(2010) Friedrich Grimminger et al.   NATURE REVIEWS DRUG DISCOVERY

Rituximab versus Cyclophosphamide for ANCA-Associated Vasculitis

(2010) John H. Stone et al.   NEW ENGLAND JOURNAL OF MEDICINE

Rituximab versus Cyclophosphamide in ANCA-Associated Renal Vasculitis

(2010) Rachel B. Jones et al.   NEW ENGLAND JOURNAL OF MEDICINE

An Oral Spleen Tyrosine Kinase (Syk) Inhibitor for Rheumatoid Arthritis

(2010) Michael E. Weinblatt et al.   NEW ENGLAND JOURNAL OF MEDICINE

Acute Renal Failure under Dasatinib Therapy

(2010) Sultan Ozkurt et al.   RENAL FAILURE

Bruton’s tyrosine kinase (Btk): function, regulation, and transformation with special emphasis on the PH domain

(2009) Abdalla J. Mohamed et al.   IMMUNOLOGICAL REVIEWS

A Spleen Tyrosine Kinase Inhibitor Reduces the Severity of Established Glomerulonephritis

(2009) J. Smith et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Preventive and therapeutic effects of imatinib in Wistar-Kyoto rats with anti-glomerular basement membrane glomerulonephritis

(2009) Masayuki Iyoda et al.   KIDNEY INTERNATIONAL

Blockade of the c-Jun amino terminal kinase prevents crescent formation and halts established anti-GBM glomerulonephritis in the rat

(2009) Frank Y Ma et al.   LABORATORY INVESTIGATION

Renal failure associated with tyrosine kinase inhibitors—Case report and review of the literature

(2009) Anat Gafter-Gvili et al.   LEUKEMIA RESEARCH

An orally bioavailable spleen tyrosine kinase inhibitor delays disease progression and prolongs survival in murine lupus

(2008) Frances Rena Bahjat et al.   ARTHRITIS AND RHEUMATISM

Renal failure and recovery associated with second-generation Bcr-Abl kinase inhibitors in imatinib-resistant chronic myelogenous leukemia

(2008) Sarah A. Holstein et al.   LEUKEMIA RESEARCH

A New Look at Platelet-Derived Growth Factor in Renal Disease

(2007) J. Floege et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY