Brutonˈs tyrosine kinase-an integral protein of B cell development that also has an essential role in the innate immune system

Bruton’s Tyrosine Kinase Mediates FcγRIIa/Toll-Like Receptor–4 Receptor Crosstalk in Human Neutrophils

(2012) Agnieszka Krupa et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Bruton's Tyrosine Kinase mediates platelet receptor-induced generation of microparticles: A potential mechanism for amplification of inflammatory responses in rheumatoid arthritis synovial joints

(2012) Jonathan Hsu et al.   IMMUNOLOGY LETTERS

The Role of the Tec Kinase Bruton's Tyrosine Kinase (Btk) in Leukocyte Recruitment

(2012) Helena Block et al.   INTERNATIONAL REVIEWS OF IMMUNOLOGY

Consequences of two naturally occurring missense mutations in the structure and function of Bruton agammaglobulinemia tyrosine kinase

(2012) Alexander Vargas-Hernández et al.   IUBMB LIFE

Tyrosine Kinase Btk Is Required for NK Cell Activation

(2012) Yan Bao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Increased Pro-inflammatory Cytokine Production After Lipopolysaccharide Stimulation in Patients with X-linked Agammaglobulinemia

(2012) María Edith González-Serrano et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Dendritic and T Cell Response to Influenza is Normal in the Patients with X-Linked Agammaglobulinemia

(2012) Yinping Liu et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Crucial role of SLP-76 and ADAP for neutrophil recruitment in mouse kidney ischemia-reperfusion injury

(2012) Helena Block et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The kinase Btk negatively regulates the production of reactive oxygen species and stimulation-induced apoptosis in human neutrophils

(2012) Fumiko Honda et al.   NATURE IMMUNOLOGY

Toll-like receptor 4–, 7–, and 8–activated myeloid cells from patients with X-linked agammaglobulinemia produce enhanced inflammatory cytokines

(2011) Thomas U. Marron et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

A Novel Role for Bruton's Tyrosine Kinase in Hepatocyte Growth Factor-mediated Immunoregulation of Dendritic Cells

(2011) Eshu Singhal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

How platelets safeguard vascular integrity

(2011) B. HO-TIN-NOÉ et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Immunoreceptor Signaling

(2011) L. E. Samelson   Cold Spring Harbor Perspectives in Biology

Neutrophil development and function critically depend on Bruton tyrosine kinase in a mouse model of X-linked agammaglobulinemia

(2010) K. Fiedler et al.   BLOOD

Tyrosine kinase Btk regulates E-selectin-mediated integrin activation and neutrophil recruitment by controlling phospholipase C (PLC)  2 and PI3K  pathways

(2010) H. Mueller et al.   BLOOD

TLR signaling and effector functions are intact in XLA neutrophils

(2010) Thomas U. Marron et al.   CLINICAL IMMUNOLOGY

Elevated cytokine production restores bone resorption by human Btk-deficient osteoclasts

(2010) Lynett Danks et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Btk-dependent Rac activation and actin rearrangement following Fc RI aggregation promotes enhanced chemotactic responses of mast cells

(2010) H. S. Kuehn et al.   JOURNAL OF CELL SCIENCE

Genetics of hypogammaglobulinemia: what do we really know?

(2009) Mary Ellen Conley   CURRENT OPINION IN IMMUNOLOGY

Bruton’s tyrosine kinase (Btk): function, regulation, and transformation with special emphasis on the PH domain

(2009) Abdalla J. Mohamed et al.   IMMUNOLOGICAL REVIEWS

Clinical Characteristics and Genotype-phenotype Correlation in 62 Patients with X-linked Agammaglobulinemia

(2009) Pamela P. W. Lee et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Genetic and demographic features of X-linked agammaglobulinemia in Eastern and Central Europe: A cohort study

(2009) Beáta Tóth et al.   MOLECULAR IMMUNOLOGY

Tyrosine Kinases Btk and Tec Regulate Osteoclast Differentiation by Linking RANK and ITAM Signals

(2008) Masahiro Shinohara et al.   CELL

The Tec Family Tyrosine Kinase Btk Regulates RANKL-induced Osteoclast Maturation

(2008) Seoung Hoon Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Clinical and Molecular Analysis of 49 Patients With X-linked Agammaglobulinemia From A Single Center in Argentina

(2008) Natalia Basile et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Analysis of Clinical Presentations of Bruton Disease: A Review of 20 Years of Accumulated Data from Pediatric Patients at Severance Hospital

(2008) Jin-Kyong Chun et al.   YONSEI MEDICAL JOURNAL

Toll-like receptor signaling is impaired in dendritic cells from patients with X-linked agammaglobulinemia

(2007) Hiromichi Taneichi et al.   CLINICAL IMMUNOLOGY

Characterization of Bruton's tyrosine kinase mutations in Mexican patients with X-linked agammaglobulinemia

(2007) G. Lopez-Herrera et al.   MOLECULAR IMMUNOLOGY