Suppression of Glomerulonephritis in Lupus-Prone NZB × NZW Mice by RN486, a Selective Inhibitor of Bruton's Tyrosine Kinase

Activated Renal Macrophages Are Markers of Disease Onset and Disease Remission in Lupus Nephritis

(2014) L. Schiffer et al.   JOURNAL OF IMMUNOLOGY

Joint European League Against Rheumatism and European Renal Association–European Dialysis and Transplant Association (EULAR/ERA-EDTA) recommendations for the management of adult and paediatric lupus nephritis

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Anti-tumor necrosis factor α treatment of interferon-α-induced murine lupus nephritis reduces the renal macrophage response but does not alter glomerular immune complex formation

(2012) Ramalingam Bethunaickan et al.   ARTHRITIS AND RHEUMATISM

Btk levels set the threshold for B-cell activation and negative selection of autoreactive B cells in mice

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Bone marrow of NZB/W mice is the major site for plasma cells resistant to dexamethasone and cyclophosphamide: Implications for the treatment of autoimmunity

(2012) Imtiaz M. Mumtaz et al.   JOURNAL OF AUTOIMMUNITY

Serum from patients with SLE instructs monocytes to promote IgG and IgA plasmablast differentiation

(2012) HyeMee Joo et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Cross-Species Transcriptional Network Analysis Defines Shared Inflammatory Responses in Murine and Human Lupus Nephritis

(2012) C. C. Berthier et al.   JOURNAL OF IMMUNOLOGY

Aberrant Macrophages Mediate Defective Kidney Repair That Triggers Nephritis in Lupus-Susceptible Mice

(2012) Y. Iwata et al.   JOURNAL OF IMMUNOLOGY

B-cell depletion in the treatment of lupus nephritis

(2012) Jon W. Gregersen et al.   Nature Reviews Nephrology

Targeting B-cells in lupus nephritis: should cautious optimism remain?

(2012) Brad H. Rovin   NEPHROLOGY DIALYSIS TRANSPLANTATION

Bruton's tyrosine kinase phosphorylates Toll-like receptor 3 to initiate antiviral response

(2012) K.-G. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

American College of Rheumatology guidelines for screening, treatment, and management of lupus nephritis

(2012) Bevra H. Hahn et al.   ARTHRITIS CARE & RESEARCH

Murine Models of Systemic Lupus Erythematosus

(2011) Daniel Perry et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

A Unique Hybrid Renal Mononuclear Phagocyte Activation Phenotype in Murine Systemic Lupus Erythematosus Nephritis

(2011) R. Bethunaickan et al.   JOURNAL OF IMMUNOLOGY

Protective and Pathogenic Roles for B Cells during Systemic Autoimmunity in NZB/W F1 Mice

(2010) K. M. Haas et al.   JOURNAL OF IMMUNOLOGY

B Cell Activating Factor (BAFF) and T Cells Cooperate to Breach B Cell Tolerance in Lupus-Prone New Zealand Black (NZB) Mice

(2010) Nan-Hua Chang et al.   PLoS One

The Bruton tyrosine kinase inhibitor PCI-32765 blocks B-cell activation and is efficacious in models of autoimmune disease and B-cell malignancy

(2010) L. A. Honigberg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Primary B Cell Immunodeficiencies: Comparisons and Contrasts

(2009) Mary Ellen Conley et al.   Annual Review of Immunology

The role of B cells in lupus pathogenesis

(2009) Emil Nashi et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Toll-like receptor 7 cooperates with IL-4 in activated B cells through antigen receptor or CD38 and induces class switch recombination and IgG1 production

(2009) Yumiko Tsukamoto et al.   MOLECULAR IMMUNOLOGY

Lupus nephritis: lessons from murine models

(2009) Anne Davidson et al.   Nature Reviews Rheumatology

Bruton's Tyrosine Kinase Separately Regulates NFκB p65RelA Activation and Cytokine Interleukin (IL)-10/IL-12 Production in TLR9-stimulated B Cells

(2008) Koon-Guan Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Btk regulates localization, in vivo activation, and class switching of anti-DNA B cells

(2008) Kristina E. Halcomb et al.   MOLECULAR IMMUNOLOGY

Mapping similarities in mTOR pathway perturbations in mouse lupus nephritis models and human lupus nephritis

(2008) Padmalatha S Reddy et al.   ARTHRITIS RESEARCH & THERAPY