Sarsasapogenin suppresses Aβ overproduction induced by high glucose in HT-22 cells

Ginsenoside Re reduces Aβ production by activating PPARγ to inhibit BACE1 in N2a/APP695 cells

(2016) Guoqiong Cao et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Astragaloside IV, a Natural PPARγ Agonist, Reduces Aβ Production in Alzheimer’s Disease Through Inhibition of BACE1

(2016) Xu Wang et al.   MOLECULAR NEUROBIOLOGY

Protective Effects of Baicalin on Aβ1–42-Induced Learning and Memory Deficit, Oxidative Stress, and Apoptosis in Rat

(2015) Haitao Ding et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Activation of mTOR signaling mediates the increased expression of AChE in high glucose condition: in vitro and in vivo evidences

(2015) Yao-Wu Liu et al.   MOLECULAR NEUROBIOLOGY

Rutin improves spatial memory in Alzheimer's disease transgenic mice by reducing Aβ oligomer level and attenuating oxidative stress and neuroinflammation

(2014) Peng-xin Xu et al.   BEHAVIOURAL BRAIN RESEARCH

Increases in β-amyloid protein in the hippocampus caused by diabetic metabolic disorder are blocked by minocycline through inhibition of NF-κB pathway activation

(2014) Zhiyou Cai et al.   Pharmacological Reports

Pioglitazone ameliorates memory deficits in streptozotocin-induced diabetic mice by reducing brain β-amyloid through PPARγ activation

(2013) Li-ping Liu et al.   ACTA PHARMACOLOGICA SINICA

Cerebroprotective effects of ibuprofen on diabetic encephalopathy in rats

(2013) Yao-Wu Liu et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Timosaponin-BII inhibits the up-regulation of BACE1 induced by Ferric Chloride in rat retina

(2012) Ju-Fang Huang et al.   BMC Complementary and Alternative Medicine

PPARγ Agonist Pioglitazone Reverses Memory Impairment and Biochemical Changes in a Mouse Model of Type 2 Diabetes Mellitus

(2012) Li-Ying Jiang et al.   CNS Neuroscience & Therapeutics

Hyperglycemia Induces the Variations of 11β-Hydroxysteroid Dehydrogenase Type 1 and Peroxisome Proliferator-Activated Receptor-γExpression in Hippocampus and Hypothalamus of Diabetic Rats

(2012) Wen-wen Qi et al.   Experimental Diabetes Research

Ginsenoside Rg1 attenuates β-amyloid generation via suppressing PPARγ-regulated BACE1 activity in N2a-APP695 cells

(2011) Li-min Chen et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Total saponins from Rhizoma Anemarrhenae ameliorate diabetes-associated cognitive decline in rats: Involvement of amyloid-beta decrease in brain

(2011) Yao-Wu Liu et al.   JOURNAL OF ETHNOPHARMACOLOGY

Ghrelin Modulates Insulin Sensitivity and Tau Phosphorylation in High Glucose-Induced Hippocampal Neurons

(2010) Ying Chen et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Insulin deficiency exacerbates cerebral amyloidosis and behavioral deficits in an Alzheimer transgenic mouse model

(2010) Xu Wang et al.   Molecular Neurodegeneration

Diabetes-accelerated memory dysfunction via cerebrovascular inflammation and A  deposition in an Alzheimer mouse model with diabetes

(2010) S. Takeda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PPARγ transcriptionally regulates the expression of insulin-degrading enzyme in primary neurons

(2009) Jing Du et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Type 1 diabetes exaggerates features of Alzheimer's disease in APP transgenic mice

(2009) Corinne G. Jolivalt et al.   EXPERIMENTAL NEUROLOGY

Downregulation of LPR1 at the blood–brain barrier in streptozotocin-induced diabetic mice

(2009) Hao Hong et al.   NEUROPHARMACOLOGY

Timosaponin AIII, a saponin isolated from Anemarrhena asphodeloides, ameliorates learning and memory deficits in mice

(2009) Bomi Lee et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Increased amyloid β-peptide (1–40) level in brain of streptozotocin-induced diabetic rats

(2008) Y. Liu et al.   NEUROSCIENCE