Protective Effects of Baicalin on Aβ1–42-Induced Learning and Memory Deficit, Oxidative Stress, and Apoptosis in Rat

Baicalin protects PC-12 cells from oxidative stress induced by hydrogen peroxide via anti-apoptotic effects

(2014) Wen-xia Zheng et al.   BRAIN INJURY

Nrf2 Regulates Neurogenesis and Protects Neural Progenitor Cells Against Aβ Toxicity

(2014) Virve Kärkkäinen et al.   STEM CELLS

Protective Effect of Bajijiasu Against β-Amyloid-Induced Neurotoxicity in PC12 Cells

(2013) Di-Ling Chen et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Baicalin attenuates focal cerebral ischemic reperfusion injury by inhibition of protease-activated receptor-1 and apoptosis

(2013) Qing-bo Zhou et al.   Chinese Journal of Integrative Medicine

Rho Kinase Inhibitor Fasudil Protects againstβ-Amyloid-Induced Hippocampal Neurodegeneration in Rats

(2013) Yun Song et al.   CNS Neuroscience & Therapeutics

Baicalin improves chronic corticosterone-induced learning and memory deficits via the enhancement of impaired hippocampal brain-derived neurotrophic factor and cAMP response element-binding protein expression in the rat

(2013) Bombi Lee et al.   Journal of Natural Medicines

Cognitive-enhancing and antioxidant activities of inhaled coriander volatile oil in amyloid β(1–42) rat model of Alzheimer's disease

(2013) Oana Cioanca et al.   PHYSIOLOGY & BEHAVIOR

Amyloid β-Peptide (1–42)-Induced Oxidative Stress in Alzheimer Disease: Importance in Disease Pathogenesis and Progression

(2012) D. Allan Butterfield et al.   ANTIOXIDANTS & REDOX SIGNALING

Mitochondria and Mitophagy

(2012) Dieter A. Kubli et al.   CIRCULATION RESEARCH

The Nrf2-antioxidant response element pathway: a target for regulating energy metabolism

(2012) Emilie E. Vomhof-DeKrey et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

The Anticonvulsant and Neuroprotective Effects of Baicalin on Pilocarpine-Induced Epileptic Model in Rats

(2012) Yang-Feng Liu et al.   NEUROCHEMICAL RESEARCH

Protective effect of cyanidin 3-O-glucoside on beta-amyloid peptide-induced cognitive impairment in rats

(2012) Lina Qin et al.   NEUROSCIENCE LETTERS

Borneol alleviates oxidative stress via upregulation of Nrf2 and Bcl-2 in SH-SY5Y cells

(2012) Jinyoung Hur et al.   PHARMACEUTICAL BIOLOGY

Inhibition of PKA attenuates memory deficits induced by β-amyloid (1–42), and decreases oxidative stress and NF-κB transcription factors

(2011) Bahareh Eftekharzadeh et al.   BEHAVIOURAL BRAIN RESEARCH

Alginate oligosaccharide protects against endoplasmic reticulum- and mitochondrial-mediated apoptotic cell death and oxidative stress

(2011) Solaleh Khoramian Tusi et al.   BIOMATERIALS

Baicalin attenuates global cerebral ischemia/reperfusion injury in gerbils via anti-oxidative and anti-apoptotic pathways

(2011) Yonggang Cao et al.   BRAIN RESEARCH BULLETIN

Therapeutic efficacy of stemazole in a beta-amyloid injection rat model of Alzheimer's disease

(2011) Mei Han et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

The phosphodiesterase-4 inhibitor rolipram reverses Aβ-induced cognitive impairment and neuroinflammatory and apoptotic responses in rats

(2011) Chuang Wang et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Baicalin prevents the production of hydrogen peroxide and oxidative stress induced by Aβ aggregation in SH-SY5Y cells

(2011) Fei Yin et al.   NEUROSCIENCE LETTERS

Potential therapeutic agents against Alzheimer’s disease from natural sources

(2010) So-Young Park   ARCHIVES OF PHARMACAL RESEARCH

Baicalin attenuates focal cerebral ischemic reperfusion injury through inhibition of nuclear factor κB p65 activation

(2010) Xia Xue et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Neuroprotective effect of baicalin on compression spinal cord injury in rats

(2010) Yang Cao et al.   BRAIN RESEARCH

Genistein ameliorates learning and memory deficits in amyloid β(1–40) rat model of Alzheimer’s disease

(2010) Maryam Bagheri et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Effects of trans-2,4-dimethoxystibene against the neurotoxicity induced by Aβ25–35 both in vitro and in vivo

(2010) Can-Jun Ruan et al.   NEUROSCIENCE RESEARCH

Neuroprotective effects of the polyphenolic antioxidant agent, Curcumin, against homocysteine-induced cognitive impairment and oxidative stress in the rat

(2010) Amin Ataie et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

2009 Alzheimer's disease facts and figures

(2009)   Alzheimers & Dementia

Drug development for Alzheimer's disease: Where are we now and where are we headed?

(2009) Marwan N. Sabbagh   American Journal Geriatric Pharmacotherapy

SK-PC-B70M confers anti-oxidant activity and reduces Aβ levels in the brain of Tg2576 mice

(2009) Ji-Seon Seo et al.   BRAIN RESEARCH

Small molecule inhibitors of Aβ-aggregation and neurotoxicity

(2009) Cheryl A. Hawkes et al.   DRUG DEVELOPMENT RESEARCH

Cellular prion protein mediates impairment of synaptic plasticity by amyloid-β oligomers

(2009) Juha Laurén et al.   NATURE

Chronic nicotine restores normal Aβ levels and prevents short-term memory and E-LTP impairment in Aβ rat model of Alzheimer's disease

(2009) Marisa Srivareerat et al.   NEUROBIOLOGY OF AGING

Baicalin, a prodrug able to reach the CNS, is a prolyl oligopeptidase inhibitor

(2008) Teresa Tarragó et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Antioxidant activity of the phenol rich fractions of leaves of Chukrasia tabularis A. Juss.

(2008) Rajbir Kaur et al.   BIORESOURCE TECHNOLOGY

Molecular mechanisms of Nrf2-mediated antioxidant response

(2008) Wenge Li et al.   MOLECULAR CARCINOGENESIS