The winding path of protein methylation research: milestones and new frontiers
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Title
The winding path of protein methylation research: milestones and new frontiers
Authors
Keywords
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Journal
NATURE REVIEWS MOLECULAR CELL BIOLOGY
Volume 18, Issue 8, Pages 517-527
Publisher
Springer Nature
Online
2017-05-17
DOI
10.1038/nrm.2017.35
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Note: Only part of the references are listed.- Molecular Recognition of Lys and Arg Methylation
- (2016) Joshua E. Beaver et al. ACS Chemical Biology
- Quantitative Profiling of the Activity of Protein Lysine Methyltransferase SMYD2 Using SILAC-Based Proteomics
- (2016) Jonathan B. Olsen et al. MOLECULAR & CELLULAR PROTEOMICS
- Comprehensive Identification of RNA-Binding Domains in Human Cells
- (2016) Alfredo Castello et al. MOLECULAR CELL
- Targeting histone methyltransferases and demethylases in clinical trials for cancer therapy
- (2016) Ludovica Morera et al. Clinical Epigenetics
- A Potent, Selective and Cell-Active Allosteric Inhibitor of Protein Arginine Methyltransferase 3 (PRMT3)
- (2015) H. Ümit Kaniskan et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Histone Methylation Dynamics and Gene Regulation Occur through the Sensing of One-Carbon Metabolism
- (2015) Samantha J. Mentch et al. Cell Metabolism
- Protein arginine methyltransferase CARM1 attenuates the paraspeckle-mediated nuclear retention of mRNAs containing IRAlus
- (2015) Shi-Bin Hu et al. GENES & DEVELOPMENT
- A selective inhibitor of PRMT5 with in vivo and in vitro potency in MCL models
- (2015) Elayne Chan-Penebre et al. Nature Chemical Biology
- Epigenetic regulation by histone demethylases in hypoxia
- (2015) Rebecca L Hancock et al. Epigenomics
- Discovery of lysine post-translational modifications through mass spectrometric detection
- (2014) Barry M. Zee et al. Essays in Biochemistry
- Selective Inhibitors of Protein Methyltransferases
- (2014) H. Ümit Kaniskan et al. JOURNAL OF MEDICINAL CHEMISTRY
- Selective Inhibition of EZH2 by EPZ-6438 Leads to Potent Antitumor Activity in EZH2-Mutant Non-Hodgkin Lymphoma
- (2014) S. K. Knutson et al. MOLECULAR CANCER THERAPEUTICS
- Intracellular α-ketoglutarate maintains the pluripotency of embryonic stem cells
- (2014) Bryce W. Carey et al. NATURE
- SMYD3 links lysine methylation of MAP3K2 to Ras-driven cancer
- (2014) Pawel K. Mazur et al. NATURE
- Non-histone protein methylation as a regulator of cellular signalling and function
- (2014) Kyle K. Biggar et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Readout of Epigenetic Modifications
- (2013) Dinshaw J. Patel et al. Annual Review of Biochemistry
- Potent inhibition of DOT1L as treatment of MLL-fusion leukemia
- (2013) S. R. Daigle et al. BLOOD
- Phosphorylation of EZH2 Activates STAT3 Signaling via STAT3 Methylation and Promotes Tumorigenicity of Glioblastoma Stem-like Cells
- (2013) Eunhee Kim et al. CANCER CELL
- Large-scale global identification of protein lysine methylation in vivo
- (2013) Xing-Jun Cao et al. Epigenetics
- Exploiting an Allosteric Binding Site of PRMT3 Yields Potent and Selective Inhibitors
- (2013) Feng Liu et al. JOURNAL OF MEDICINAL CHEMISTRY
- Immunoaffinity Enrichment and Mass Spectrometry Analysis of Protein Methylation
- (2013) Ailan Guo et al. MOLECULAR & CELLULAR PROTEOMICS
- A General Molecular Affinity Strategy for Global Detection and Proteomic Analysis of Lysine Methylation
- (2013) Kaitlyn E. Moore et al. MOLECULAR CELL
- A Method for Systematic Mapping of Protein Lysine Methylation Identifies Functions for HP1β in DNA Damage Response
- (2013) Huadong Liu et al. MOLECULAR CELL
- NNMT promotes epigenetic remodeling in cancer by creating a metabolic methylation sink
- (2013) Olesya A Ulanovskaya et al. Nature Chemical Biology
- Defining efficient enzyme-cofactor pairs for bioorthogonal profiling of protein methylation
- (2013) K. Islam et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- SET for life: biochemical activities and biological functions of SET domain-containing proteins
- (2013) Hans-Martin Herz et al. TRENDS IN BIOCHEMICAL SCIENCES
- Protein methylation at the surface and buried deep: thinking outside the histone box
- (2013) Steven G. Clarke TRENDS IN BIOCHEMICAL SCIENCES
- The Histone Demethylase KDM1A Sustains the Oncogenic Potential of MLL-AF9 Leukemia Stem Cells
- (2012) William J. Harris et al. CANCER CELL
- Inhibition of -KG-dependent histone and DNA demethylases by fumarate and succinate that are accumulated in mutations of FH and SDH tumor suppressors
- (2012) M. Xiao et al. GENES & DEVELOPMENT
- Bioorthogonal Profiling of Protein Methylation Using Azido Derivative of S-Adenosyl-l-methionine
- (2012) Kabirul Islam et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- IDH mutation impairs histone demethylation and results in a block to cell differentiation
- (2012) Chao Lu et al. NATURE
- A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response
- (2012) Laurens Kruidenier et al. NATURE
- Inhibition of the LSD1 (KDM1A) demethylase reactivates the all-trans-retinoic acid differentiation pathway in acute myeloid leukemia
- (2012) Tino Schenk et al. NATURE MEDICINE
- Histone methylation: a dynamic mark in health, disease and inheritance
- (2012) Eric L. Greer et al. NATURE REVIEWS GENETICS
- Perceiving the epigenetic landscape through histone readers
- (2012) Catherine A Musselman et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Influence of Threonine Metabolism on S-Adenosylmethionine and Histone Methylation
- (2012) N. Shyh-Chang et al. SCIENCE
- FAD-dependent lysine-specific demethylase-1 regulates cellular energy expenditure
- (2012) Shinjiro Hino et al. Nature Communications
- Dishevelled3 is a novel arginine methyl transferase substrate
- (2012) Rama Kamesh Bikkavilli et al. Scientific Reports
- Selective Killing of Mixed Lineage Leukemia Cells by a Potent Small-Molecule DOT1L Inhibitor
- (2011) Scott R. Daigle et al. CANCER CELL
- Deciphering arginine methylation: Tudor tells the tale
- (2011) Chen Chen et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Protein Arginine Methyltransferase 5 Regulates ERK1/2 Signal Transduction Amplitude and Cell Fate Through CRAF
- (2011) P. Andreu-Perez et al. Science Signaling
- Structural Basis of Substrate Methylation and Inhibition of SMYD2
- (2011) Andrew D. Ferguson et al. STRUCTURE
- A proteomic approach for the identification of novel lysine methyltransferase substrates
- (2011) Dan Levy et al. Epigenetics & Chromatin
- Enzymatic Site-Specific Functionalization of Protein Methyltransferase Substrates with Alkynes for Click Labeling
- (2010) Wibke Peters et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- The Common Feature of Leukemia-Associated IDH1 and IDH2 Mutations Is a Neomorphic Enzyme Activity Converting α-Ketoglutarate to 2-Hydroxyglutarate
- (2010) Patrick S. Ward et al. CANCER CELL
- The Language of Histone Crosstalk
- (2010) Jung-Shin Lee et al. CELL
- Quantitative Interaction Proteomics and Genome-wide Profiling of Epigenetic Histone Marks and Their Readers
- (2010) Michiel Vermeulen et al. CELL
- Histone Methyl Transferases and Demethylases; Can They Link Metabolism and Transcription?
- (2010) Raffaele Teperino et al. Cell Metabolism
- A Chemical Method for Labeling Lysine Methyltransferase Substrates
- (2010) Olivier Binda et al. CHEMBIOCHEM
- Methylation of the Retinoblastoma Tumor Suppressor by SMYD2
- (2010) Louis A. Saddic et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- G9a and Glp Methylate Lysine 373 in the Tumor Suppressor p53
- (2010) Jing Huang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Biochemical, Structural, and Biological Evaluation of Tranylcypromine Derivatives as Inhibitors of Histone Demethylases LSD1 and LSD2
- (2010) Claudia Binda et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Somatic mutations altering EZH2 (Tyr641) in follicular and diffuse large B-cell lymphomas of germinal-center origin
- (2010) Ryan D Morin et al. NATURE GENETICS
- Lysine methylation of the NF-κB subunit RelA by SETD6 couples activity of the histone methyltransferase GLP at chromatin to tonic repression of NF-κB signaling
- (2010) Dan Levy et al. NATURE IMMUNOLOGY
- Characterization of an antagonistic switch between histone H3 lysine 27 methylation and acetylation in the transcriptional regulation of Polycomb group target genes
- (2010) Diego Pasini et al. NUCLEIC ACIDS RESEARCH
- Coordinated activities of wild-type plus mutant EZH2 drive tumor-associated hypertrimethylation of lysine 27 on histone H3 (H3K27) in human B-cell lymphomas
- (2010) C. J. Sneeringer et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Fast signals and slow marks: the dynamics of histone modifications
- (2010) Teresa K. Barth et al. TRENDS IN BIOCHEMICAL SCIENCES
- Global turnover of histone post-translational modifications and variants in human cells
- (2010) Barry M Zee et al. Epigenetics & Chromatin
- CBP-mediated acetylation of histone H3 lysine 27 antagonizes Drosophila Polycomb silencing
- (2009) F. Tie et al. DEVELOPMENT
- Functional involvement of Tudor and dPRMT5 in the piRNA processing pathway in Drosophila germlines
- (2009) Kazumichi M Nishida et al. EMBO JOURNAL
- Proteomic analysis of murine Piwi proteins reveals a role for arginine methylation in specifying interaction with Tudor family members
- (2009) V. V. Vagin et al. GENES & DEVELOPMENT
- GlycineN-Methyltransferase and Regulation ofS-Adenosylmethionine Levels
- (2009) Zigmund Luka et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Cancer-associated IDH1 mutations produce 2-hydroxyglutarate
- (2009) Lenny Dang et al. NATURE
- Loss of the Mili-interacting Tudor domain–containing protein-1 activates transposons and alters the Mili-associated small RNA profile
- (2009) Michael Reuter et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Arginine methylation regulates the p53 response
- (2008) Martin Jansson et al. NATURE CELL BIOLOGY
- Protein lysine methyltransferase G9a acts on non-histone targets
- (2008) Philipp Rathert et al. Nature Chemical Biology
- The effect of H3K79 dimethylation and H4K20 trimethylation on nucleosome and chromatin structure
- (2008) Xu Lu et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
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