Biology and evolution of poorly differentiated neuroendocrine tumors
Published 2017 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Biology and evolution of poorly differentiated neuroendocrine tumors
Authors
Keywords
-
Journal
NATURE MEDICINE
Volume 23, Issue 6, Pages 1-10
Publisher
Springer Nature
Online
2017-06-07
DOI
10.1038/nm.4341
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Whole-genome landscape of pancreatic neuroendocrine tumours
- (2017) Aldo Scarpa et al. NATURE
- Reprogramming to resist
- (2017) Kathleen Kelly et al. SCIENCE
- SOX2 promotes lineage plasticity and antiandrogen resistance in TP53 - and RB1 -deficient prostate cancer
- (2017) Ping Mu et al. SCIENCE
- Rb1 and Trp53 cooperate to suppress prostate cancer lineage plasticity, metastasis, and antiandrogen resistance
- (2017) Sheng Yu Ku et al. SCIENCE
- N-Myc Induces an EZH2-Mediated Transcriptional Program Driving Neuroendocrine Prostate Cancer
- (2016) Etienne Dardenne et al. CANCER CELL
- N-Myc Drives Neuroendocrine Prostate Cancer Initiated from Human Prostate Epithelial Cells
- (2016) John K. Lee et al. CANCER CELL
- Next-Generation Sequencing of Pulmonary Large Cell Neuroendocrine Carcinoma Reveals Small Cell Carcinoma-like and Non-Small Cell Carcinoma-like Subsets
- (2016) N. Rekhtman et al. CLINICAL CANCER RESEARCH
- Neuroendocrine Tumors of the Prostate: Emerging Insights from Molecular Data and Updates to the 2016 World Health Organization Classification
- (2016) David S. Priemer et al. ENDOCRINE PATHOLOGY
- Targeting mutant p53 in cancer: a long road to precision therapy
- (2016) Fiamma Mantovani et al. FEBS Journal
- Genetic requirement forMycland efficacy of RNA Pol I inhibition in mouse models of small cell lung cancer
- (2016) Dong-Wook Kim et al. GENES & DEVELOPMENT
- Multiple mechanisms disrupt the let-7 microRNA family in neuroblastoma
- (2016) John T. Powers et al. NATURE
- Genomic analyses identify molecular subtypes of pancreatic cancer
- (2016) Peter Bailey et al. NATURE
- Substantial interindividual and limited intraindividual genomic diversity among tumors from men with metastatic prostate cancer
- (2016) Akash Kumar et al. NATURE MEDICINE
- Divergent clonal evolution of castration-resistant neuroendocrine prostate cancer
- (2016) Himisha Beltran et al. NATURE MEDICINE
- Towards a new classification of gastroenteropancreatic neuroendocrine neoplasms
- (2016) Mark Kidd et al. Nature Reviews Clinical Oncology
- PD-1 Blockade with Pembrolizumab in Advanced Merkel-Cell Carcinoma
- (2016) Paul T. Nghiem et al. NEW ENGLAND JOURNAL OF MEDICINE
- The Master Neural Transcription Factor BRN2 Is an Androgen Receptor–Suppressed Driver of Neuroendocrine Differentiation in Prostate Cancer
- (2016) Jennifer L. Bishop et al. Cancer Discovery
- Identification and Targeting of Long-Term Tumor-Propagating Cells in Small Cell Lung Cancer
- (2016) Nadine S. Jahchan et al. Cell Reports
- ASCL1 and NEUROD1 Reveal Heterogeneity in Pulmonary Neuroendocrine Tumors and Regulate Distinct Genetic Programs
- (2016) Mark D. Borromeo et al. Cell Reports
- Tumorigenic Activity of Merkel Cell Polyomavirus T Antigens Expressed in the Stratified Epithelium of Mice
- (2015) M. E. Spurgeon et al. CANCER RESEARCH
- The Molecular Taxonomy of Primary Prostate Cancer
- (2015) Adam Abeshouse et al. CELL
- Inhibition of Pluripotency Networks by the Rb Tumor Suppressor Restricts Reprogramming and Tumorigenesis
- (2015) Michael S. Kareta et al. Cell Stem Cell
- Well-Differentiated Neuroendocrine Tumors with a Morphologically Apparent High-Grade Component: A Pathway Distinct from Poorly Differentiated Neuroendocrine Carcinomas
- (2015) L. H. Tang et al. CLINICAL CANCER RESEARCH
- Merkel Cell Polyomavirus Small T Antigen Is Oncogenic in Transgenic Mice
- (2015) Monique E. Verhaegen et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- The Comparative Pathology of Genetically Engineered Mouse Models for Neuroendocrine Carcinomas of the Lung
- (2015) Adi F. Gazdar et al. Journal of Thoracic Oncology
- Transformation from non-small-cell lung cancer to small-cell lung cancer: molecular drivers and cells of origin
- (2015) Matthew G Oser et al. LANCET ONCOLOGY
- Comprehensive genomic profiles of small cell lung cancer
- (2015) Julie George et al. NATURE
- DNA methylation in small cell lung cancer defines distinct disease subtypes and correlates with high expression of EZH2
- (2015) J T Poirier et al. ONCOGENE
- Mutational landscape determines sensitivity to PD-1 blockade in non-small cell lung cancer
- (2015) N. A. Rizvi et al. SCIENCE
- RB loss in resistant EGFR mutant lung adenocarcinomas that transform to small-cell lung cancer
- (2015) Matthew J. Niederst et al. Nature Communications
- The Placental Gene PEG10 Promotes Progression of Neuroendocrine Prostate Cancer
- (2015) Shusuke Akamatsu et al. Cell Reports
- Merkel Cell Polyomavirus Small T Antigen Induces Cancer and Embryonic Merkel Cell Proliferation in a Transgenic Mouse Model
- (2015) Masahiro Shuda et al. PLoS One
- Nordic guidelines 2014 for diagnosis and treatment of gastroenteropancreatic neuroendocrine neoplasms
- (2014) Eva Tiensuu Janson et al. ACTA ONCOLOGICA
- Proposed Morphologic Classification of Prostate Cancer With Neuroendocrine Differentiation
- (2014) Jonathan I. Epstein et al. AMERICAN JOURNAL OF SURGICAL PATHOLOGY
- Drugging MYCN through an Allosteric Transition in Aurora Kinase A
- (2014) William Clay Gustafson et al. CANCER CELL
- Genetic and Clonal Dissection of Murine Small Cell Lung Carcinoma Progression by Genome Sequencing
- (2014) David G. McFadden et al. CELL
- Neuroendocrine Tumors of the Pancreas: Current Concepts and Controversies
- (2014) Michelle D. Reid et al. ENDOCRINE PATHOLOGY
- Models of neuroendocrine prostate cancer
- (2014) Lisa D Berman-Booty et al. ENDOCRINE-RELATED CANCER
- PTEN Is a Potent Suppressor of Small Cell Lung Cancer
- (2014) Min Cui et al. MOLECULAR CANCER RESEARCH
- Comprehensive molecular profiling of lung adenocarcinoma
- (2014) Eric A. Collisson et al. NATURE
- Small cell carcinoma of the ovary, hypercalcemic type, displays frequent inactivating germline and somatic mutations in SMARCA4
- (2014) Pilar Ramos et al. NATURE GENETICS
- Recurrent SMARCA4 mutations in small cell carcinoma of the ovary
- (2014) Petar Jelinic et al. NATURE GENETICS
- Drugging the p53 pathway: understanding the route to clinical efficacy
- (2014) Kian Hoe Khoo et al. NATURE REVIEWS DRUG DISCOVERY
- A Cre-conditional MYCN-driven neuroblastoma mouse model as an improved tool for preclinical studies
- (2014) K Althoff et al. ONCOGENE
- Extra-prostatic Transgene-associated Neoplastic Lesions in Transgenic Adenocarcinoma of the Mouse Prostate (TRAMP) Mice
- (2014) Lisa D. Berman-Booty et al. TOXICOLOGIC PATHOLOGY
- Frequent mutations in chromatin-remodelling genes in pulmonary carcinoids
- (2014) Lynnette Fernandez-Cuesta et al. Nature Communications
- MYC, MAX, and Small Cell Lung Cancer
- (2014) C. M. Rudin et al. Cancer Discovery
- Comparison of WHO Classifications (2004, 2010), the Hochwald Grading System, and AJCC and ENETS Staging Systems in Predicting Prognosis in Locoregional Well-differentiated Pancreatic Neuroendocrine Tumors
- (2013) Ta-Chiang Liu et al. AMERICAN JOURNAL OF SURGICAL PATHOLOGY
- Targets in small cell lung cancer
- (2013) Beverly A. Teicher BIOCHEMICAL PHARMACOLOGY
- Small Molecule Inhibitors of Aurora-A Induce Proteasomal Degradation of N-Myc in Childhood Neuroblastoma
- (2013) Markus Brockmann et al. CANCER CELL
- High Fidelity Patient-Derived Xenografts for Accelerating Prostate Cancer Discovery and Drug Development
- (2013) D. Lin et al. CANCER RESEARCH
- Punctuated Evolution of Prostate Cancer Genomes
- (2013) Sylvan C. Baca et al. CELL
- Rb Loss Is Characteristic of Prostatic Small Cell Neuroendocrine Carcinoma
- (2013) H.-L. Tan et al. CLINICAL CANCER RESEARCH
- Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor–Resistant Disease
- (2013) Kadoaki Ohashi et al. JOURNAL OF CLINICAL ONCOLOGY
- Neuroendocrine tumours—challenges in the diagnosis and classification of pulmonary neuroendocrine tumours
- (2013) M A den Bakker et al. JOURNAL OF CLINICAL PATHOLOGY
- Development and Characteristics of Preclinical Experimental Models for the Research of Rare Neuroendocrine Bladder Cancer
- (2013) Thomas Hofner et al. JOURNAL OF UROLOGY
- DNA Methylation Alterations Exhibit Intraindividual Stability and Interindividual Heterogeneity in Prostate Cancer Metastases
- (2013) M. J. Aryee et al. Science Translational Medicine
- Neuroendocrine tumors of the gynecologic tract: Select topics
- (2013) Marjan Rouzbahman et al. SEMINARS IN DIAGNOSTIC PATHOLOGY
- Small Cell and Large Cell Neuroendocrine Carcinomas of the Pancreas are Genetically Similar and Distinct From Well-differentiated Pancreatic Neuroendocrine Tumors
- (2012) Shinichi Yachida et al. AMERICAN JOURNAL OF SURGICAL PATHOLOGY
- Mapping the Hallmarks of Lung Adenocarcinoma with Massively Parallel Sequencing
- (2012) Marcin Imielinski et al. CELL
- Pathogenesis of prostatic small cell carcinoma involves the inactivation of the P53 pathway
- (2012) Hongbing Chen et al. ENDOCRINE-RELATED CANCER
- Ipilimumab in Combination With Paclitaxel and Carboplatin As First-Line Treatment in Stage IIIB/IV Non–Small-Cell Lung Cancer: Results From a Randomized, Double-Blind, Multicenter Phase II Study
- (2012) Thomas J. Lynch et al. JOURNAL OF CLINICAL ONCOLOGY
- From sequence to molecular pathology, and a mechanism driving the neuroendocrine phenotype in prostate cancer
- (2012) Anna V Lapuk et al. JOURNAL OF PATHOLOGY
- An Integrated Genomic Approach to Identify Predictive Biomarkers of Response to the Aurora Kinase Inhibitor PF-03814735
- (2012) K. E. Hook et al. MOLECULAR CANCER THERAPEUTICS
- Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes
- (2012) Andrew V. Biankin et al. NATURE
- The mutational landscape of lethal castration-resistant prostate cancer
- (2012) Catherine S. Grasso et al. NATURE
- Exome sequencing identifies recurrent SPOP, FOXA1 and MED12 mutations in prostate cancer
- (2012) Christopher E Barbieri et al. NATURE GENETICS
- Comprehensive genomic analysis identifies SOX2 as a frequently amplified gene in small-cell lung cancer
- (2012) Charles M Rudin et al. NATURE GENETICS
- Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer
- (2012) Martin Peifer et al. NATURE GENETICS
- A framework for identification of actionable cancer genome dependencies in small cell lung cancer
- (2012) M. L. Sos et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Proteomic Profiling Identifies Dysregulated Pathways in Small Cell Lung Cancer and Novel Therapeutic Targets Including PARP1
- (2012) Lauren Averett Byers et al. Cancer Discovery
- Prostate Epithelial Pten/TP53 Loss Leads to Transformation of Multipotential Progenitors and Epithelial to Mesenchymal Transition
- (2011) Philip Martin et al. AMERICAN JOURNAL OF PATHOLOGY
- The origin of neuroendocrine tumors and the neural crest saga
- (2011) Juan Rosai MODERN PATHOLOGY
- Genotypic and Histological Evolution of Lung Cancers Acquiring Resistance to EGFR Inhibitors
- (2011) L. V. Sequist et al. Science Translational Medicine
- Molecular Characterization of Neuroendocrine Prostate Cancer and Identification of New Drug Targets
- (2011) H. Beltran et al. Cancer Discovery
- Integrative Genomic Profiling of Human Prostate Cancer
- (2010) Barry S. Taylor et al. CANCER CELL
- Loss of p130 Accelerates Tumor Development in a Mouse Model for Human Small-Cell Lung Carcinoma
- (2010) B. E. Schaffer et al. CANCER RESEARCH
- Neuroendocrine prostate cancer xenografts with large-cell and small-cell features derived from a single patient's tumor: Morphological, immunohistochemical, and gene expression profiles
- (2010) Ana Aparicio et al. PROSTATE
- Is Nonsmall Cell Type High-grade Neuroendocrine Carcinoma of the Tubular Gastrointestinal Tract a Distinct Disease Entity?
- (2008) Jinru Shia et al. AMERICAN JOURNAL OF SURGICAL PATHOLOGY
- Ionizing Radiation Induces Prostate Cancer Neuroendocrine Differentiation through Interplay of CREB and ATF2: Implications for Disease Progression
- (2008) X. Deng et al. CANCER RESEARCH
- Somatic mutations affect key pathways in lung adenocarcinoma
- (2008) Li Ding et al. NATURE
- Clonal Integration of a Polyomavirus in Human Merkel Cell Carcinoma
- (2008) H. Feng et al. SCIENCE
Become a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get StartedAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started