Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer

ROS1 Rearrangements Define a Unique Molecular Class of Lung Cancers

(2012) Kristin Bergethon et al.   JOURNAL OF CLINICAL ONCOLOGY

CREBBP HAT domain mutations prevail in relapse cases of high hyperdiploid childhood acute lymphoblastic leukemia

(2012) A Inthal et al.   LEUKEMIA

Identification of new ALK and RET gene fusions from colorectal and lung cancer biopsies

(2012) Doron Lipson et al.   NATURE MEDICINE

KIF5B-RET fusions in lung adenocarcinoma

(2012) Takashi Kohno et al.   NATURE MEDICINE

RET, ROS1 and ALK fusions in lung cancer

(2012) Kengo Takeuchi et al.   NATURE MEDICINE

A Functional Role for Tumor Cell Heterogeneity in a Mouse Model of Small Cell Lung Cancer

(2011) Joaquim Calbo et al.   CANCER CELL

Lung Cancer Signatures in Plasma Based on Proteome Profiling of Mouse Tumor Models

(2011) Ayumu Taguchi et al.   CANCER CELL

Cell of Origin of Small Cell Lung Cancer: Inactivation of Trp53 and Rb1 in Distinct Cell Types of Adult Mouse Lung

(2011) Kate D. Sutherland et al.   CANCER CELL

The Eph-Receptor A7 Is a Soluble Tumor Suppressor for Follicular Lymphoma

(2011) Elisa Oricchio et al.   CELL

Slit-Robo signaling induces malignant transformation through Hakai-mediated E-cadherin degradation during colorectal epithelial cell carcinogenesis

(2011) Wei-Jie Zhou et al.   CELL RESEARCH

Nuclear factor I/B is an oncogene in small cell lung cancer

(2011) A. L. Dooley et al.   GENES & DEVELOPMENT

Small-cell lung cancer

(2011) Jan P van Meerbeeck et al.   LANCET

CREBBP mutations in relapsed acute lymphoblastic leukaemia

(2011) Charles G. Mullighan et al.   NATURE

Inactivating mutations of acetyltransferase genes in B-cell lymphoma

(2011) Laura Pasqualucci et al.   NATURE

Frequent mutation of histone-modifying genes in non-Hodgkin lymphoma

(2011) Ryan D. Morin et al.   NATURE

Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma

(2011) Ignacio Varela et al.   NATURE

Initial genome sequencing and analysis of multiple myeloma

(2011) Michael A. Chapman et al.   NATURE

The genomic complexity of primary human prostate cancer

(2011) Michael F. Berger et al.   NATURE

Integrated genomic analyses of ovarian carcinoma

(2011) D. Bell et al.   NATURE

Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia

(2011) Xose S. Puente et al.   NATURE

A crucial requirement for Hedgehog signaling in small cell lung cancer

(2011) Kwon-Sik Park et al.   NATURE MEDICINE

Benchmarking of Mutation Diagnostics in Clinical Lung Cancer Specimens

(2011) Silvia Querings et al.   PLoS One

Inhibitor-Sensitive FGFR1 Amplification in Human Non-Small Cell Lung Cancer

(2011) Amit Dutt et al.   PLoS One

Genotypic and Histological Evolution of Lung Cancers Acquiring Resistance to EGFR Inhibitors

(2011) L. V. Sequist et al.   Science Translational Medicine

Mutations in the DDR2 Kinase Gene Identify a Novel Therapeutic Target in Squamous Cell Lung Cancer

(2011) Peter S. Hammerman et al.   Cancer Discovery

SLIT2 Attenuation during Lung Cancer Progression Deregulates  -Catenin and E-Cadherin and Associates with Poor Prognosis

(2010) R.-C. Tseng et al.   CANCER RESEARCH

Loss of p130 Accelerates Tumor Development in a Mouse Model for Human Small-Cell Lung Carcinoma

(2010) B. E. Schaffer et al.   CANCER RESEARCH

CBP/p300 double null cells reveal effect of coactivator level and diversity on CREB transactivation

(2010) Lawryn H Kasper et al.   EMBO JOURNAL

ERG rearrangement is specific to prostate cancer and does not occur in any other common tumor

(2010) Veit J Scheble et al.   MODERN PATHOLOGY

Genome remodelling in a basal-like breast cancer metastasis and xenograft

(2010) Li Ding et al.   NATURE

Anaplastic Lymphoma Kinase Inhibition in Non–Small-Cell Lung Cancer

(2010) Eunice L. Kwak et al.   NEW ENGLAND JOURNAL OF MEDICINE

Array comparative genomic hybridization-based characterization of genetic alterations in pulmonary neuroendocrine tumors

(2010) J. Voortman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Frequent Mutations of Chromatin Remodeling Gene ARID1A in Ovarian Clear Cell Carcinoma

(2010) Siân Jones et al.   SCIENCE

Frequent and Focal FGFR1 Amplification Associates with Therapeutically Tractable FGFR1 Dependency in Squamous Cell Lung Cancer

(2010) J. Weiss et al.   Science Translational Medicine

Fast and accurate short read alignment with Burrows-Wheeler transform

(2009) H. Li et al.   BIOINFORMATICS

Modes of p53 Regulation

(2009) Jan-Philipp Kruse et al.   CELL

Lung tumours with neuroendocrine differentiation

(2009) William D. Travis   EUROPEAN JOURNAL OF CANCER

Fragile histidine triad protein: structure, function, and its association with tumorogenesis

(2009) Md. Imtaiyaz Hassan et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Predicting drug susceptibility of non–small cell lung cancers based on genetic lesions

(2009) Martin L. Sos et al.   JOURNAL OF CLINICAL INVESTIGATION

A small-cell lung cancer genome with complex signatures of tobacco exposure

(2009) Erin D. Pleasance et al.   NATURE

A comprehensive catalogue of somatic mutations from a human cancer genome

(2009) Erin D. Pleasance et al.   NATURE

SOX2 is an amplified lineage-survival oncogene in lung and esophageal squamous cell carcinomas

(2009) Adam J Bass et al.   NATURE GENETICS

Bronchopulmonary neuroendocrine tumors

(2008) Bjorn I. Gustafsson et al.   CANCER

PIK3CA Mutations and Copy Number Gains in Human Lung Cancers

(2008) H. Yamamoto et al.   CANCER RESEARCH

Mapping short DNA sequencing reads and calling variants using mapping quality scores

(2008) H. Li et al.   GENOME RESEARCH

Somatic mutations affect key pathways in lung adenocarcinoma

(2008) Li Ding et al.   NATURE

The structural basis of protein acetylation by the p300/CBP transcriptional coactivator

(2008) Xin Liu et al.   NATURE

Progress and Challenges in Selected Areas of Tobacco Carcinogenesis

(2007) Stephen S. Hecht   CHEMICAL RESEARCH IN TOXICOLOGY