From sequence to molecular pathology, and a mechanism driving the neuroendocrine phenotype in prostate cancer

Cancer statistics, 2012

(2012) Rebecca Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Chromothripsis and Human Disease: Piecing Together the Shattering Process

(2012) Christopher A. Maher et al.   CELL

Can Genomics Bend the Cost Curve?

(2012) Katrina Armstrong   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Integrated genome and transcriptome sequencing identifies a novel form of hybrid and aggressive prostate cancer

(2012) Chunxiao Wu et al.   JOURNAL OF PATHOLOGY

Next Generation Sequencing of Prostate Cancer from a Patient Identifies a Deficiency of Methylthioadenosine Phosphorylase, an Exploitable Tumor Target

(2012) C. C. Collins et al.   MOLECULAR CANCER THERAPEUTICS

Comrad: detection of expressed rearrangements by integrated analysis of RNA-Seq and low coverage genome sequence data

(2011) Andrew McPherson et al.   BIOINFORMATICS

Novel therapeutics for the management of castration-resistant prostate cancer (CRPC)

(2011) Daniel J. Lee et al.   BJU INTERNATIONAL

Common Structural and Epigenetic Changes in the Genome of Castration-Resistant Prostate Cancer

(2011) T. W. Friedlander et al.   CANCER RESEARCH

Massive Genomic Rearrangement Acquired in a Single Catastrophic Event during Cancer Development

(2011) Philip J. Stephens et al.   CELL

Alternatively spliced androgen receptor variants

(2011) Scott M Dehm et al.   ENDOCRINE-RELATED CANCER

New Therapies for Castration-Resistant Prostate Cancer: Efficacy and Safety

(2011) Himisha Beltran et al.   EUROPEAN UROLOGY

The advent of personal genome sequencing

(2011) Radoje Drmanac   GENETICS IN MEDICINE

Prostate cancer and inflammation: the evidence

(2011) Karen S Sfanos et al.   HISTOPATHOLOGY

Human prostate cancer metastases target the hematopoietic stem cell niche to establish footholds in mouse bone marrow

(2011) Yusuke Shiozawa et al.   JOURNAL OF CLINICAL INVESTIGATION

When catastrophe strikes a cell

(2011) Jose M. C. Tubio et al.   NATURE

The genomic complexity of primary human prostate cancer

(2011) Michael F. Berger et al.   NATURE

Overexpression of Full-Length ETV1 Transcripts in Clinical Prostate Cancer Due to Gene Translocation

(2011) Delila Gasi et al.   PLoS One

Molecular classification of prostate cancer using curated expression signatures

(2011) E. K. Markert et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Personalized Oncology Through Integrative High-Throughput Sequencing: A Pilot Study

(2011) S. Roychowdhury et al.   Science Translational Medicine

Molecular Characterization of Neuroendocrine Prostate Cancer and Identification of New Drug Targets

(2011) H. Beltran et al.   Cancer Discovery

An EMT–Driven Alternative Splicing Program Occurs in Human Breast Cancer and Modulates Cellular Phenotype

(2011) Irina M. Shapiro et al.   PLoS Genetics

Evaluation of statistical methods for normalization and differential expression in mRNA-Seq experiments

(2010) James H Bullard et al.   BMC BIOINFORMATICS

Integrative Genomic Profiling of Human Prostate Cancer

(2010) Barry S. Taylor et al.   CANCER CELL

Castration resistance in human prostate cancer is conferred by a frequently occurring androgen receptor splice variant

(2010) Shihua Sun et al.   JOURNAL OF CLINICAL INVESTIGATION

ETS family-associated gene fusions in Japanese prostate cancer: analysis of 194 radical prostatectomy samples

(2010) Yohei Miyagi et al.   MODERN PATHOLOGY

TMPRSS2–ERG gene fusion is associated with low Gleason scores and not with high-grade morphological features

(2010) Samson W Fine et al.   MODERN PATHOLOGY

Clusterin Facilitates COMMD1 and I- B Degradation to Enhance NF- B Activity in Prostate Cancer Cells

(2010) A. Zoubeidi et al.   MOLECULAR CANCER RESEARCH

Exon-Level Microarray Analyses Identify Alternative Splicing Programs in Breast Cancer

(2010) A. Lapuk et al.   MOLECULAR CANCER RESEARCH

Alternative expression analysis by RNA sequencing

(2010) Malachi Griffith et al.   NATURE METHODS

Constitutively active androgen receptor splice variants expressed in castration-resistant prostate cancer require full-length androgen receptor

(2010) P. A. Watson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Use of irinotecan for treatment of small cell carcinoma of the prostate

(2010) Wei-Lin Tung et al.   PROSTATE

Development of Personalized Tumor Biomarkers Using Massively Parallel Sequencing

(2010) R. J. Leary et al.   Science Translational Medicine

Syndecan-2 overexpression regulates adhesion and migration through cooperation with integrin α2

(2009) Sojoong Choi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

A Novel Androgen Receptor Splice Variant Is Up-regulated during Prostate Cancer Progression and Promotes Androgen Depletion-Resistant Growth

(2009) Z. Guo et al.   CANCER RESEARCH

Nuclear Receptor-Induced Chromosomal Proximity and DNA Breaks Underlie Specific Translocations in Cancer

(2009) Chunru Lin et al.   CELL

Circos: An information aesthetic for comparative genomics

(2009) M. Krzywinski et al.   GENOME RESEARCH

The basics of epithelial-mesenchymal transition

(2009) Raghu Kalluri et al.   JOURNAL OF CLINICAL INVESTIGATION

Mutational evolution in a lobular breast tumour profiled at single nucleotide resolution

(2009) Sohrab P. Shah et al.   NATURE

An integrative approach to reveal driver gene fusions from paired-end sequencing data in cancer

(2009) Xiao-Song Wang et al.   NATURE BIOTECHNOLOGY

ETS gene fusions in prostate cancer

(2009) Jeremy P. Clark et al.   Nature Reviews Urology

The Pfam protein families database

(2009) Robert D. Finn et al.   NUCLEIC ACIDS RESEARCH

Expression and prognostic role of syndecan-2 in prostate cancer

(2009) A Popović et al.   PROSTATE CANCER AND PROSTATIC DISEASES

Role of the TMPRSS2-ERG Gene Fusion in Prostate Cancer

(2008) Scott A. Tomlins et al.   NEOPLASIA