Transcriptional risk scores link GWAS to eQTLs and predict complications in Crohn's disease
Published 2017 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Transcriptional risk scores link GWAS to eQTLs and predict complications in Crohn's disease
Authors
Keywords
-
Journal
NATURE GENETICS
Volume 49, Issue 10, Pages 1517-1521
Publisher
Springer Nature
Online
2017-08-14
DOI
10.1038/ng.3936
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Prediction of complicated disease course for children newly diagnosed with Crohn's disease: a multicentre inception cohort study
- (2017) Subra Kugathasan et al. LANCET
- Genome-wide association study identifies distinct genetic contributions to prognosis and susceptibility in Crohn's disease
- (2017) James C Lee et al. NATURE GENETICS
- Limited statistical evidence for shared genetic effects of eQTLs and autoimmune-disease-associated loci in three major immune-cell types
- (2017) Sung Chun et al. NATURE GENETICS
- Colocalization of GWAS and eQTL Signals Detects Target Genes
- (2016) Farhad Hormozdiari et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Inherited determinants of Crohn's disease and ulcerative colitis phenotypes: a genetic association study
- (2016) Isabelle Cleynen et al. LANCET
- Integration of summary data from GWAS and eQTL studies predicts complex trait gene targets
- (2016) Zhihong Zhu et al. NATURE GENETICS
- Developing and evaluating polygenic risk prediction models for stratified disease prevention
- (2016) Nilanjan Chatterjee et al. NATURE REVIEWS GENETICS
- Blood and Intestine eQTLs from an Anti-TNF-Resistant Crohn's Disease Cohort Inform IBD Genetic Association Loci
- (2016) Antonio F Di Narzo et al. Clinical and Translational Gastroenterology
- GITR+ regulatory T cells in the treatment of autoimmune diseases
- (2015) Maria Grazia Petrillo et al. AUTOIMMUNITY REVIEWS
- Genetics of Inflammatory Bowel Diseases
- (2015) Dermot P.B. McGovern et al. GASTROENTEROLOGY
- Improved integrative framework combining association data with gene expression features to prioritize Crohn's disease genes
- (2015) Kaida Ning et al. HUMAN MOLECULAR GENETICS
- Characterization of Expression Quantitative Trait Loci in the Human Colon
- (2015) Tarjinder Singh et al. INFLAMMATORY BOWEL DISEASES
- Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations
- (2015) Jimmy Z Liu et al. NATURE GENETICS
- Fine mapping of type 1 diabetes susceptibility loci and evidence for colocalization of causal variants with lymphoid gene enhancers
- (2015) Suna Onengut-Gumuscu et al. NATURE GENETICS
- Immunopathogenesis of IBD: current state of the art
- (2015) Heitor S. P. de Souza et al. Nature Reviews Gastroenterology & Hepatology
- The role of regulatory variation in complex traits and disease
- (2015) Frank W. Albert et al. NATURE REVIEWS GENETICS
- The Genotype-Tissue Expression (GTEx) pilot analysis: Multitissue gene regulation in humans
- (2015) et al. SCIENCE
- Expression quantitative trait locus analysis for translational medicine
- (2015) Greg Gibson et al. Genome Medicine
- HTSeq--a Python framework to work with high-throughput sequencing data
- (2014) S. Anders et al. BIOINFORMATICS
- Genetics of gene expression in immunity to infection
- (2014) Benjamin P Fairfax et al. CURRENT OPINION IN IMMUNOLOGY
- Costimulatory Molecule DNAM-1 Is Essential for Optimal Differentiation of Memory Natural Killer Cells during Mouse Cytomegalovirus Infection
- (2014) Tsukasa Nabekura et al. IMMUNITY
- Pediatric Crohn disease patients exhibit specific ileal transcriptome and microbiome signature
- (2014) Yael Haberman et al. JOURNAL OF CLINICAL INVESTIGATION
- The contribution of genetic variants to disease depends on the ruler
- (2014) John S. Witte et al. NATURE REVIEWS GENETICS
- Intersection of population variation and autoimmunity genetics in human T cell activation
- (2014) C. J. Ye et al. SCIENCE
- Common Genetic Variants Modulate Pathogen-Sensing Responses in Human Dendritic Cells
- (2014) M. N. Lee et al. SCIENCE
- Bayesian Test for Colocalisation between Pairs of Genetic Association Studies Using Summary Statistics
- (2014) Claudia Giambartolomei et al. PLoS Genetics
- Expression Quantitative Trait Loci Analysis Identifies Associations Between Genotype and Gene Expression in Human Intestine
- (2013) Boyko Kabakchiev et al. GASTROENTEROLOGY
- Increased Effectiveness of Early Therapy With Anti-Tumor Necrosis Factor-α vs an Immunomodulator in Children With Crohn's Disease
- (2013) Thomas D. Walters et al. GASTROENTEROLOGY
- Systematic identification of trans eQTLs as putative drivers of known disease associations
- (2013) Harm-Jan Westra et al. NATURE GENETICS
- TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions
- (2013) Daehwan Kim et al. GENOME BIOLOGY
- The sva package for removing batch effects and other unwanted variation in high-throughput experiments
- (2012) Jeffrey T. Leek et al. BIOINFORMATICS
- Genome-wide efficient mixed-model analysis for association studies
- (2012) Xiang Zhou et al. NATURE GENETICS
- Increase of regulatory T cells in ileal mucosa of untreated pediatric Crohn's disease patients
- (2011) Dag Henrik Reikvam et al. SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY
- Supervised normalization of microarrays
- (2010) Brigham H. Mecham et al. BIOINFORMATICS
- Pediatric modification of the Montreal classification for inflammatory bowel disease
- (2010) Arie Levine et al. INFLAMMATORY BOWEL DISEASES
- The Genetic Interpretation of Area under the ROC Curve in Genomic Profiling
- (2010) Naomi R. Wray et al. PLoS Genetics
- The Sequence Alignment/Map format and SAMtools
- (2009) H. Li et al. BIOINFORMATICS
- edgeR: a Bioconductor package for differential expression analysis of digital gene expression data
- (2009) M. D. Robinson et al. BIOINFORMATICS
- Mapping and quantifying mammalian transcriptomes by RNA-Seq
- (2008) Ali Mortazavi et al. NATURE METHODS
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started