Plasticity, dynamics, and inhibition of emerging tetracycline resistance enzymes

Development of a platform for the discovery and practical synthesis of new tetracycline antibiotics

(2016) Fan Liu et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

The Structure of the Antibiotic Deactivating,N-hydroxylating Rifampicin Monooxygenase

(2016) Li-Kai Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Emergence of plasmid-mediated colistin resistance mechanism MCR-1 in animals and human beings in China: a microbiological and molecular biological study

(2016) Yi-Yun Liu et al.   LANCET INFECTIOUS DISEASES

The Tetracycline Destructases: A Novel Family of Tetracycline-Inactivating Enzymes

(2015) Kevin J. Forsberg et al.   CHEMISTRY & BIOLOGY

Tackling antibiotic resistance: the environmental framework

(2015) Thomas U. Berendonk et al.   NATURE REVIEWS MICROBIOLOGY

An analysis of FDA-approved drugs for infectious disease: antibacterial agents

(2014) Michael S. Kinch et al.   DRUG DISCOVERY TODAY

Bacterial phylogeny structures soil resistomes across habitats

(2014) Kevin J. Forsberg et al.   NATURE

Putative dioxygen-binding sites and recognition of tigecycline and minocycline in the tetracycline-degrading monooxygenase TetX

(2013) Gesa Volkers et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

New β-Lactamase Inhibitors: a Therapeutic Renaissance in an MDR World

(2013) Sarah M. Drawz et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Molecular Epidemiology and Mechanisms of Tigecycline Resistance in Clinical Isolates of Acinetobacter baumannii from a Chinese University Hospital

(2013) Mei Deng et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Antibacterial Activity of Eravacycline (TP-434), a Novel Fluorocycline, against Hospital and Community Pathogens

(2013) J. A. Sutcliffe et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

In VitroandIn VivoAntibacterial Activities of Omadacycline, a Novel Aminomethylcycline

(2013) A. B. Macone et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

The human flavoproteome

(2013) Wolf-Dieter Lienhart et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Multidrug-resistant tet(X)-containing hospital isolates in Sierra Leone

(2013) Tomasz A. Leski et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Uncovering the Enzymes that Catalyze the Final Steps in Oxytetracycline Biosynthesis

(2013) Peng Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Flavoenzymes: Versatile catalysts in biosynthetic pathways

(2012) Christopher T. Walsh et al.   NATURAL PRODUCT REPORTS

The Shared Antibiotic Resistome of Soil Bacteria and Human Pathogens

(2012) K. J. Forsberg et al.   SCIENCE

Overview of theCCP4 suite and current developments

(2011) Martyn D. Winn et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Structural basis for a new tetracycline resistance mechanism relying on the TetX monooxygenase

(2011) Gesa Volkers et al.   FEBS LETTERS

Antibiotic resistance is ancient

(2011) Vanessa M. D’Costa et al.   NATURE

XDS

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Structural and mechanistic basis for a new mode of glycosyltransferase inhibition

(2010) Thomas Pesnot et al.   Nature Chemical Biology

Chemical decay of an antibiotic inverts selection for resistance

(2010) Adam C Palmer et al.   Nature Chemical Biology

Call of the wild: antibiotic resistance genes in natural environments

(2010) Heather K. Allen et al.   NATURE REVIEWS MICROBIOLOGY

Analysis of the Legionella longbeachae Genome and Transcriptome Uncovers Unique Strategies to Cause Legionnaires' Disease

(2010) Christel Cazalet et al.   PLoS Genetics

MolProbity: all-atom structure validation for macromolecular crystallography

(2009) Vincent B. Chen et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Characterization of a New Metallo- -Lactamase Gene, blaNDM-1, and a Novel Erythromycin Esterase Gene Carried on a Unique Genetic Structure in Klebsiella pneumoniae Sequence Type 14 from India

(2009) D. Yong et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

The tetracycline resistome

(2009) Maulik Thaker et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Evidence of Increasing Antibiotic Resistance Gene Abundances in Archived Soils since 1940

(2009) Charles W. Knapp et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Sphingobacteriumsp. strain PM2-P1-29 harbours a functionaltet(X) gene encoding for the degradation of tetracycline

(2009) S. Ghosh et al.   JOURNAL OF APPLIED MICROBIOLOGY

Bad Bugs, No Drugs: No ESKAPE! An Update from the Infectious Diseases Society of America

(2008) Helen W. Boucher et al.   CLINICAL INFECTIOUS DISEASES