Structural and Biochemical Properties of Novel Self-Cleaving Ribozymes

Crystal structure of Pistol, a class of self-cleaving ribozyme

(2017) Laura A. Nguyen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular Dynamics Study of Twister Ribozyme: Role of Mg2+ Ions and the Hydrogen-Bonding Network in the Active Site

(2016) Melek N. Ucisik et al.   BIOCHEMISTRY

Two Active Site Divalent Ions in the Crystal Structure of the Hammerhead Ribozyme Bound to a Transition State Analogue

(2016) Aamir Mir et al.   BIOCHEMISTRY

The Novel Chemical Mechanism of the Twister Ribozyme

(2016) Timothy J. Wilson et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Pistol ribozyme adopts a pseudoknot fold facilitating site-specific in-line cleavage

(2016) Aiming Ren et al.   Nature Chemical Biology

Unwinding the twister ribozyme: from structure to mechanism

(2016) Jennifer Gebetsberger et al.   Wiley Interdisciplinary Reviews-RNA

Ribozymes and the mechanisms that underlie RNA catalysis

(2016) Timothy J. Wilson et al.   Frontiers of Chemical Science and Engineering

A Mini-Twister Variant and Impact of Residues/Cations on the Phosphodiester Cleavage of this Ribozyme Class

(2015) Marija Košutić et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Two Divalent Metal Ions and Conformational Changes Play Roles in the Hammerhead Ribozyme Cleavage Reaction

(2015) Aamir Mir et al.   BIOCHEMISTRY

Crystal structure of the Varkud satellite ribozyme

(2015) Nikolai B Suslov et al.   Nature Chemical Biology

New classes of self-cleaving ribozymes revealed by comparative genomics analysis

(2015) Zasha Weinberg et al.   Nature Chemical Biology

Biochemical analysis of pistol self-cleaving ribozymes

(2015) Kimberly A. Harris et al.   RNA

Biochemical analysis of hatchet self-cleaving ribozymes

(2015) Sanshu Li et al.   RNA

Chemistry and Biology of Self-Cleaving Ribozymes

(2015) Randi M. Jimenez et al.   TRENDS IN BIOCHEMICAL SCIENCES

Crystal structure and mechanistic investigation of the twister ribozyme

(2014) Yijin Liu et al.   Nature Chemical Biology

The RNA World: molecular cooperation at the origins of life

(2014) Paul G. Higgs et al.   NATURE REVIEWS GENETICS

Structural basis for the fast self-cleavage reaction catalyzed by the twister ribozyme

(2014) D. Eiler et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

In-line alignment and Mg2+ coordination at the cleavage site of the env22 twister ribozyme

(2014) Aiming Ren et al.   Nature Communications

RNA catalyses nuclear pre-mRNA splicing

(2013) Sebastian M. Fica et al.   NATURE

A widespread self-cleaving ribozyme class is revealed by bioinformatics

(2013) Adam Roth et al.   Nature Chemical Biology

Visualizing Group II Intron Catalysis through the Stages of Splicing

(2012) Marco Marcia et al.   CELL

General Acid–Base Catalysis Mediated by Nucleobases in the Hairpin Ribozyme

(2012) Stephanie Kath-Schorr et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The ydaO motif is an ATP-sensing riboswitch in Bacillus subtilis

(2012) Peter Y Watson et al.   Nature Chemical Biology

Understanding the Acid-Base Properties of Adenosine: The Intrinsic Basicities of N1, N3 and N7

(2011) Larisa E. Kapinos  et al.   CHEMISTRY-A EUROPEAN JOURNAL

Processing and Translation Initiation of Non-long Terminal Repeat Retrotransposons by Hepatitis Delta Virus (HDV)-like Self-cleaving Ribozymes

(2011) Dana J. Ruminski et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of an hepatitis delta virus-like ribozyme at the mRNA 5′-end of the L1Tc retrotransposon from Trypanosoma cruzi

(2011) Francisco J. Sánchez-Luque et al.   NUCLEIC ACIDS RESEARCH

An expanded collection and refined consensus model of glmS ribozymes

(2011) P. J. McCown et al.   RNA

Identification of Hammerhead Ribozymes in All Domains of Life Reveals Novel Structural Variations

(2011) Jonathan Perreault et al.   PLoS Computational Biology

A 1.9 Å Crystal Structure of the HDV Ribozyme Precleavage Suggests both Lewis Acid and General Acid Mechanisms Contribute to Phosphodiester Cleavage

(2010) Jui-Hui Chen et al.   BIOCHEMISTRY

R2 Retrotransposons Encode a Self-Cleaving Ribozyme for Processing from an rRNA Cotranscript

(2010) D. G. Eickbush et al.   MOLECULAR AND CELLULAR BIOLOGY

Nucleobase-mediated general acid-base catalysis in the Varkud satellite ribozyme

(2010) T. J. Wilson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nucleases: diversity of structure, function and mechanism

(2010) Wei Yang   QUARTERLY REVIEWS OF BIOPHYSICS

The Origins of the RNA World

(2010) M. P. Robertson et al.   Cold Spring Harbor Perspectives in Biology

Small Self-cleaving Ribozymes

(2010) A. R. Ferre-D'Amare et al.   Cold Spring Harbor Perspectives in Biology

Structural insights into RNA splicing

(2009) Navtej Toor et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Probing General Acid Catalysis in the Hammerhead Ribozyme

(2009) Jason M. Thomas et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Widespread Occurrence of Self-Cleaving Ribozymes

(2009) C.-H. T. Webb et al.   SCIENCE

RNA Folding: Thermodynamic and Molecular Descriptions of the Roles of Ions

(2008) David E. Draper   BIOPHYSICAL JOURNAL

Role of Mg2+in Hammerhead Ribozyme Catalysis from Molecular Simulation

(2008) Tai-Sung Lee et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The ionic environment determines ribozyme cleavage rate by modulation of nucleobase pK a

(2008) M. D. Smith et al.   RNA

Mapping metal-binding sites in the catalytic domain of bacterial RNase P RNA

(2008) A. V. Kazantsev et al.   RNA

Crystal Structure of a Self-Spliced Group II Intron

(2008) N. Toor et al.   SCIENCE