Cancer Chemoprevention by Phytochemicals: Nature’s Healing Touch

Pharmacokinetics and in vivo delivery of curcumin by copolymeric mPEG-PCL micelles

(2017) Hamidreza Kheiri Manjili et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

MC37, a new mono-carbonyl curcumin analog, induces G2/M cell cycle arrest and mitochondria-mediated apoptosis in human colorectal cancer cells

(2017) Baoxia Liang et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Curcumin Attenuates N-Nitrosodiethylamine-Induced Liver Injury in Mice by Utilizing the Method of Metabonomics

(2017) Peiyu Qiu et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Liquid chromatography coupled with tandem mass spectrometry (LC–MS/MS) based bioavailability determination of the major classes of phytochemicals

(2017) Evgenios Stylos et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Enhanced colloidal stability, solubility and rapid dissolution of resveratrol by nanocomplexation with soy protein isolate

(2017) Naisarg Pujara et al.   JOURNAL OF COLLOID AND INTERFACE SCIENCE

A review on biogenic synthesis of ZnO nanoparticles using plant extracts and microbes: A prospect towards green chemistry

(2017) Shakeel Ahmed et al.   JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY

Recent advances in green nanoparticulate systems for drug delivery: efficient delivery and safety concern

(2017) Pik-Ling Lam et al.   Nanomedicine

A Curcumin Analog, GO-Y078, Effectively Inhibits Angiogenesis through Actin Disorganization

(2016) Shunsuke Sugiyama et al.   Anti-Cancer Agents in Medicinal Chemistry

The Warburg effect: 80 years on

(2016) Michelle Potter et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Curcumin directly inhibits the transport activity of GLUT1

(2016) Leesha K. Gunnink et al.   BIOCHIMIE

Cell Permeating Nano-Complexes of Amphiphilic Polyelectrolytes Enhance Solubility, Stability, and Anti-Cancer Efficacy of Curcumin

(2016) Munazza T. Fatima et al.   BIOMACROMOLECULES

Anti-inflammatory and antioxidant properties of a novel resveratrol–salicylate hybrid analog

(2016) Fahad S. Aldawsari et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Development of curcumin–cyclodextrin/cellulose nanocrystals complexes: New anticancer drug delivery systems

(2016) Gautier M.A. Ndong Ntoutoume et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Deubiquitination and Stabilization of PD-L1 by CSN5

(2016) Seung-Oe Lim et al.   CANCER CELL

Zinc induces epithelial to mesenchymal transition in human lung cancer H460 cells via superoxide anion-dependent mechanism

(2016) Chuanpit Ninsontia et al.   Cancer Cell International

Curcumin analog EF24 induces apoptosis via ROS-dependent mitochondrial dysfunction in human colorectal cancer cells

(2016) Guodong He et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Comparative analysis of the relative potential of silver, Zinc-oxide and titanium-dioxide nanoparticles against UVB-induced DNA damage for the prevention of skin carcinogenesis

(2016) Nikhil Tyagi et al.   CANCER LETTERS

Honokiol suppresses pancreatic tumor growth, metastasis and desmoplasia by interfering with tumor–stromal cross-talk

(2016) Courey Averett et al.   CARCINOGENESIS

Lipid Based Nanosystems for Curcumin: Past, Present and Future

(2016) Aditya Nayak P. et al.   CURRENT PHARMACEUTICAL DESIGN

2,2′-Fluorine mono-carbonyl curcumin induce reactive oxygen species-Mediated apoptosis in Human lung cancer NCI-H460 cells

(2016) Guo-Yun Liu et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Resveratrol inhibits Hexokinases II mediated glycolysis in non-small cell lung cancer via targeting Akt signaling pathway

(2016) Wei Li et al.   EXPERIMENTAL CELL RESEARCH

Enhancing the bioaccessibility of hydrophobic bioactive agents using mixed colloidal dispersions: Curcumin-loaded zein nanoparticles plus digestible lipid nanoparticles

(2016) Liqiang Zou et al.   FOOD RESEARCH INTERNATIONAL

Epigallocatechin gallate potentially abrogates fluoride induced lung oxidative stress, inflammation via Nrf2/Keap1 signaling pathway in rats: An in-vivo and in-silico study

(2016) Thangapandiyan Shanmugam et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Docosahexaenoic acid liposomes for targeting chronic inflammatory diseases and cancer: an in vitro assessment

(2016) Amr Alaarg et al.   International Journal of Nanomedicine

The resveratrol analog HS-1793 enhances radiosensitivity of mouse-derived breast cancer cells under hypoxic conditions

(2016) Yoo Jin Choi et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

pH-sensitive micelles based on acid-labile pluronic F68–curcumin conjugates for improved tumor intracellular drug delivery

(2016) Xiao-Bin Fang et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Curcumin Induces Apoptosis of Colorectal Cancer Stem Cells by Coupling with CD44 Marker

(2016) Yu-Ting Huang et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Natural Products as Sources of New Drugs from 1981 to 2014

(2016) David J. Newman et al.   JOURNAL OF NATURAL PRODUCTS

Chemopreventive agents targeting tumor microenvironment

(2016) Sharada H. Sharma et al.   LIFE SCIENCES

Small-Molecule Disruption of the Myb/p300 Cooperation Targets Acute Myeloid Leukemia Cells

(2016) Sagar Uttarkar et al.   MOLECULAR CANCER THERAPEUTICS

Prevention and treatment of cancers by immune modulating nutrients

(2016) Naveena B. Janakiram et al.   MOLECULAR NUTRITION & FOOD RESEARCH

The bounty of nature for changing the cancer landscape

(2016) Aamir Ahmad et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Multiple regulations of Keap1/Nrf2 system by dietary phytochemicals

(2016) Si Qin et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Curcumin Micelles Remodel Tumor Microenvironment and Enhance Vaccine Activity in an Advanced Melanoma Model

(2016) Yao Lu et al.   MOLECULAR THERAPY

Promiscuous Effects of Some Phenolic Natural Products on Inflammation at Least in Part Arise from Their Ability to Modulate the Expression of Global Regulators, Namely microRNAs

(2016) Esmerina Tili et al.   MOLECULES

Natural Deep Eutectic Solvents (NADES) as a Tool for Bioavailability Improvement: Pharmacokinetics of Rutin Dissolved in Proline/Glycine after Oral Administration in Rats: Possible Application in Nutraceuticals

(2016) Marta Faggian et al.   MOLECULES

Cancer Metabolism: Fueling More than Just Growth

(2016) Namgyu Lee et al.   MOLECULES AND CELLS

Docosahexaenoic Acid Induces Growth Suppression on Epithelial Ovarian Cancer Cells More Effectively than Eicosapentaenoic Acid

(2016) Xiao-Hui Wan et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Gold-conjugated resveratrol nanoparticles attenuate the invasion and MMP-9 and COX-2 expression in breast cancer cells

(2016) SUN YOUNG PARK et al.   ONCOLOGY REPORTS

A novel double carbonyl analog of curcumin induces the apoptosis of human lung cancer H460 cells via the activation of the endoplasmic reticulum stress signaling pathway

(2016) Hui Ye et al.   ONCOLOGY REPORTS

Curcumin inhibits hypoxia-induced epithelial-mesenchymal transition in pancreatic cancer cells via suppression of the hedgehog signaling pathway

(2016) LEI CAO et al.   ONCOLOGY REPORTS

Diamond Nanoparticles Modify Curcumin Activity: In Vitro Studies on Cancer and Normal Cells and In Ovo Studies on Chicken Embryo Model

(2016) Barbara Strojny et al.   PLoS One

The Curcumin Analog C-150, Influencing NF-κB, UPR and Akt/Notch Pathways Has Potent Anticancer Activity In Vitro and In Vivo

(2016) László Hackler et al.   PLoS One

Increased Intracellular Reactive Oxygen Species Mediates the Anti-Cancer Effects of WZ35 via Activating Mitochondrial Apoptosis Pathway in Prostate Cancer Cells

(2016) Minxiao Chen et al.   PROSTATE

Vitamin C induces apoptosis in AGS cells via production of ROS of mitochondria

(2016) Jae Young Lim et al.   Oncology Letters

Resveratrol Interferes with IL1-β-Induced Pro-Inflammatory Paracrine Interaction between Primary Chondrocytes and Macrophages

(2016) Emeric Limagne et al.   Nutrients

Honokiol bis-dichloroacetate (Honokiol DCA) demonstrates activity in vemurafenib-resistant melanoma in vivo

(2016) Michael Y. Bonner et al.   Oncotarget

Deep sequencing and in silico analyses identify MYB-regulated gene networks and signaling pathways in pancreatic cancer

(2016) Shafquat Azim et al.   Scientific Reports

Cancer Therapy by Catechins Involves Redox Cycling of Copper Ions and Generation of Reactive Oxygen Species

(2016) Mohd Farhan et al.   Toxins

EF24 Suppresses Invasion and Migration of Hepatocellular Carcinoma CellsIn Vitrovia Inhibiting the Phosphorylation of Src

(2016) Ran Zhao et al.   Biomed Research International

A liposomal formulation of the synthetic curcumin analog EF24 (Lipo-EF24) inhibits pancreatic cancer progression: towards future combination therapies

(2016) Savita Bisht et al.   JOURNAL OF NANOBIOTECHNOLOGY

A Standardized Chemically Modified Curcuma longa Extract Modulates IRAK-MAPK Signaling in Inflammation and Potentiates Cytotoxicity

(2016) Minakshi Rana et al.   Frontiers in Pharmacology

Time and Circumstances: Cancer Cell Metabolism at Various Stages of Disease Progression

(2016) Georg F. Weber   Frontiers in Oncology

Glucose is a key driver for GLUT1-mediated nanoparticles internalization in breast cancer cells

(2016) Leonardo Venturelli et al.   Scientific Reports

Curcumin Nanoformulation for Cervical Cancer Treatment

(2016) Mohd S. Zaman et al.   Scientific Reports

EF24 inhibits tumor growth and metastasis via suppressing NF-kappaB dependent pathways in human cholangiocarcinoma

(2016) Da-long Yin et al.   Scientific Reports

A Novel Resveratrol Based Tubulin Inhibitor Induces Mitotic Arrest and Activates Apoptosis in Cancer Cells

(2016) Elizabeth Thomas et al.   Scientific Reports

Exploring new ways of regulation by resveratrol involving miRNAs, with emphasis on inflammation

(2015) Norbert Latruffe et al.   Annals of the New York Academy of Sciences

A Curcumin Derivative That Inhibits Vinyl Carbamate-Induced Lung Carcinogenesis via Activation of the Nrf2 Protective Response

(2015) Tao Shen et al.   ANTIOXIDANTS & REDOX SIGNALING

Resveratrol induces chemosensitization to 5-fluorouracil through up-regulation of intercellular junctions, Epithelial-to-mesenchymal transition and apoptosis in colorectal cancer

(2015) Constanze Buhrmann et al.   BIOCHEMICAL PHARMACOLOGY

Hyaluronic Acid Engineered Nanomicelles Loaded with 3,4-Difluorobenzylidene Curcumin for Targeted Killing of CD44+ Stem-Like Pancreatic Cancer Cells

(2015) Prashant Kesharwani et al.   BIOMACROMOLECULES

BDMC-A, an analog of curcumin, inhibits markers of invasion, angiogenesis, and metastasis in breast cancer cells via NF-κB pathway—A comparative study with curcumin

(2015) Kumaravel Mohankumar et al.   BIOMEDICINE & PHARMACOTHERAPY

Heteroaromatic analogs of the resveratrol analog DMU-212 as potent anti-cancer agents

(2015) Narsimha Reddy Penthala et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Curcumin potentiates antitumor activity of 5-fluorouracil in a 3D alginate tumor microenvironment of colorectal cancer

(2015) Mehdi Shakibaei et al.   BMC CANCER

Curcumin analog WZ35 induced cell death via ROS-dependent ER stress and G2/M cell cycle arrest in human prostate cancer cells

(2015) Xiuhua Zhang et al.   BMC CANCER

FLLL12 induces apoptosis in lung cancer cells through a p53/p73-independent but death receptor 5-dependent pathway

(2015) Abedul Haque et al.   CANCER LETTERS

Effect of Combined Treatment with Ursolic Acid and Resveratrol on Skin Tumor Promotion by 12-O-Tetradecanoylphorbol-13-Acetate

(2015) J. Cho et al.   Cancer Prevention Research

Nanoparticles increase the efficacy of cancer chemopreventive agents in cells exposed to cigarette smoke condensate

(2015) Alessandra Pulliero et al.   CARCINOGENESIS

Metabolic Competition in the Tumor Microenvironment Is a Driver of Cancer Progression

(2015) Chih-Hao Chang et al.   CELL

Modification of Antitumor Immunity and Tumor Microenvironment by Resveratrol in Mouse Renal Tumor Model

(2015) Liang Chen et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

Personalized Preclinical Trials in BRAF Inhibitor-Resistant Patient-Derived Xenograft Models Identify Second-Line Combination Therapies

(2015) C. Krepler et al.   CLINICAL CANCER RESEARCH

Hyaluronic acid-conjugated polyamidoamine dendrimers for targeted delivery of 3,4-difluorobenzylidene curcumin to CD44 overexpressing pancreatic cancer cells

(2015) Prashant Kesharwani et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Parenterally administrable nano-micelles of 3,4-difluorobenzylidene curcumin for treating pancreatic cancer

(2015) Prashant Kesharwani et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

An update on Curcuma as a functional food in the control of cancer and inflammation

(2015) Moshe Schaffer et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Targeted nanomedicine for prostate cancer therapy: docetaxel and curcumin co-encapsulated lipid–polymer hybrid nanoparticles for the enhanced anti-tumor activityin vitroandin vivo

(2015) Jieke Yan et al.   DRUG DELIVERY

The use of plant-derived bioactive compounds to target cancer stem cells and modulate tumor microenvironment

(2015) Francesca Pistollato et al.   FOOD AND CHEMICAL TOXICOLOGY

Plumbagin-silver nanoparticle formulations enhance the cellular uptake of plumbagin and its antiproliferative activities

(2015) Prakash Appadurai et al.   IET Nanobiotechnology

Poly(d,l-lactic acid)-glycerol-based nanoparticles for curcumin delivery

(2015) In-Soo Yoon et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Resveratrol-salicylate derivatives as selective DNMT3 inhibitors and anticancer agents

(2015) Fahad S. Aldawsari et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Polymeric nanocapsules prevent oxidation of core-loaded molecules: evidence based on the effects of docosahexaenoic acid and neuroprostane on breast cancer cells proliferation

(2015) Jérôme Roy et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Enhanced anticancer properties of lomustine in conjunction with docosahexaenoic acid in glioblastoma cell lines

(2015) Kevin A. Harvey et al.   JOURNAL OF NEUROSURGERY

Synergistically Improved Anti-tumor Efficacy by Co-delivery Doxorubicin and Curcumin Polymeric Micelles

(2015) Jinling Wang et al.   MACROMOLECULAR BIOSCIENCE

Curcumin, Inflammation, and Chronic Diseases: How Are They Linked?

(2015) Yan He et al.   MOLECULES

Silver nanoparticles protect human keratinocytes against UVB radiation-induced DNA damage and apoptosis: potential for prevention of skin carcinogenesis

(2015) Sumit Arora et al.   Nanomedicine-Nanotechnology Biology and Medicine

Sequential release of epigallocatechin gallate and paclitaxel from PLGA-casein core/shell nanoparticles sensitizes drug-resistant breast cancer cells

(2015) Sreeja Narayanan et al.   Nanomedicine-Nanotechnology Biology and Medicine

Self-carried curcumin nanoparticles for in vitro and in vivo cancer therapy with real-time monitoring of drug release

(2015) Jinfeng Zhang et al.   Nanoscale

Targeting mitochondria metabolism for cancer therapy

(2015) Samuel E Weinberg et al.   Nature Chemical Biology

Resveratrol inhibits hypoxia-driven ROS-induced invasive and migratory ability of pancreatic cancer cells via suppression of the Hedgehog signaling pathway

(2015) WEI LI et al.   ONCOLOGY REPORTS

Effects of curcumin on cancer cell mitochondrial function and potential monitoring with 18F-FDG uptake

(2015) KYUNG-HO JUNG et al.   ONCOLOGY REPORTS

Epigallocatechin Gallate/Layered Double Hydroxide Nanohybrids: Preparation, Characterization, and In Vitro Anti-Tumor Study

(2015) Seyedeh Sara Shafiei et al.   PLoS One

Long Term Effect of Curcumin in Restoration of Tumour Suppressor p53 and Phase-II Antioxidant Enzymes via Activation of Nrf2 Signalling and Modulation of Inflammation in Prevention of Cancer

(2015) Laxmidhar Das et al.   PLoS One

Curcumin Analog DM-1 in Monotherapy or Combinatory Treatment with Dacarbazine as a Strategy to Inhibit In Vivo Melanoma Progression

(2015) Fernanda Faião-Flores et al.   PLoS One

MicroRNA-33b, upregulated by EF24, a curcumin analog, suppresses the epithelial-to-mesenchymal transition (EMT) and migratory potential of melanoma cells by targeting HMGA2

(2015) Pu Zhang et al.   TOXICOLOGY LETTERS

Molecular Targets of Naturopathy in Cancer Research: Bridge to Modern Medicine

(2015) Aamir Ahmad et al.   Nutrients

ROS generation mediates the anti-cancer effects of WZ35 via activating JNK and ER stress apoptotic pathways in gastric cancer

(2015) Peng Zou et al.   Oncotarget

Liposome encapsulated curcumin-difluorinated (CDF) inhibits the growth of cisplatin resistant head and neck cancer stem cells

(2015) Saroj K. Basak et al.   Oncotarget

Plumbagin Nanoparticles Induce Dose and pH Dependent Toxicity on Prostate Cancer Cells.

(2015) Harikrishnan Nair et al.   Current Drug Delivery

Resveratrol Targets in Inflammation

(2015) Hiroyasu Inoue et al.   Endocrine Metabolic & Immune Disorders-Drug Targets

Mitochondrial Modulation by Epigallocatechin 3-Gallate Ameliorates Cisplatin Induced Renal Injury through Decreasing Oxidative/Nitrative Stress, Inflammation and NF-kB in Mice

(2015) Hao Pan et al.   PLoS One

Plumbagin attenuates cancer cell growth and osteoclast formation in the bone microenvironment of mice

(2014) Wei Yan et al.   ACTA PHARMACOLOGICA SINICA

Targeting Cancer with Nano-Bullets: Curcumin, EGCG, Resveratrol and Quercetin on Flying Carpets

(2014) Aliye Aras et al.   Asian Pacific Journal of Cancer Prevention

Anti-cancer activity of curcumin loaded nanoparticles in prostate cancer

(2014) Murali M. Yallapu et al.   BIOMATERIALS

Synthesis, characterization, molecular docking and anti-tubercular activity of Plumbagin–Isoniazid Analog and its β-cyclodextrin conjugate

(2014) Prasad Dandawate et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Resveratrol inhibits estrogen-induced breast carcinogenesis through induction of NRF2-mediated protective pathways

(2014) Bhupendra Singh et al.   CARCINOGENESIS

Design of novel multifunctional targeting nano-carrier drug delivery system based on CD44 receptor and tumor microenvironment pH condition

(2014) Daquan Chen et al.   DRUG DELIVERY

Interferon gamma induced by resveratrol analog, HS-1793, reverses the properties of tumor associated macrophages

(2014) Soo Kyung Jeong et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Caging of plumbagin on silver nanoparticles imparts selectivity and sensitivity to plumbagin for targeted cancer cell apoptosis

(2014) N. Duraipandy et al.   Metallomics

3,4,5,4′-trans-tetramethoxystilbene (DMU-212) modulates the activation of NF-κB, AP-1, and STAT3 transcription factors in rat liver carcinogenesis induced by initiation-promotion regimen

(2014) Michał Cichocki et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Cancer-specific interruption of glucose metabolism by resveratrol is mediated through inhibition of Akt/GLUT1 axis in ovarian cancer cells

(2014) HyeRan Gwak et al.   MOLECULAR CARCINOGENESIS

Validating Antimetastatic Effects of Natural Products in an Engineered Microfluidic Platform Mimicking Tumor Microenvironment

(2014) Yiming Niu et al.   MOLECULAR PHARMACEUTICS

Excellent anti-proliferative and pro-apoptotic effects of (−)-epigallocatechin-3-gallate encapsulated in chitosan nanoparticles on human melanoma cell growth both in vitro and in vivo

(2014) Imtiaz A. Siddiqui et al.   Nanomedicine-Nanotechnology Biology and Medicine

Recent advances in personalized lung cancer medicine

(2014) Ross A Okimoto et al.   Personalized Medicine

Study to Evaluate Molecular Mechanics behind Synergistic Chemo-Preventive Effects of Curcumin and Resveratrol during Lung Carcinogenesis

(2014) Anshoo Malhotra et al.   PLoS One

Curcumin Suppresses Crosstalk between Colon Cancer Stem Cells and Stromal Fibroblasts in the Tumor Microenvironment: Potential Role of EMT

(2014) Constanze Buhrmann et al.   PLoS One

The Polyphenols (−)-Epigallocatechin-3-Gallate and Luteolin Synergistically Inhibit TGF-β-Induced Myofibroblast Phenotypes through RhoA and ERK Inhibition

(2014) Alana L. Gray et al.   PLoS One

Targeted Regulation of PI3K/Akt/mTOR/NF-κB Signaling by Indole Compounds and their Derivatives: Mechanistic Details and Biological Implications for Cancer Therapy

(2013) Aamir Ahmad et al.   Anti-Cancer Agents in Medicinal Chemistry

Exosome derived from epigallocatechin gallate treated breast cancer cells suppresses tumor growth by inhibiting tumor-associated macrophage infiltration and M2 polarization

(2013) Ji-Young Jang et al.   BMC CANCER

Hypoxia Triggers Hedgehog-Mediated Tumor-Stromal Interactions in Pancreatic Cancer

(2013) T. R. Spivak-Kroizman et al.   CANCER RESEARCH

Quercetin and epigallocatechin gallate inhibit glucose uptake and metabolism by breast cancer cells by an estrogen receptor-independent mechanism

(2013) Liliana Moreira et al.   EXPERIMENTAL CELL RESEARCH

Tumor necrosis factor alpha induces Warburg-like metabolism and is reversed by anti-inflammatory curcumin in breast epithelial cells

(2013) Roger A. Vaughan et al.   INTERNATIONAL JOURNAL OF CANCER

Digalloylresveratrol, a novel resveratrol analog inhibits the growth of human pancreatic cancer cells

(2013) Philipp Saiko et al.   INVESTIGATIONAL NEW DRUGS

Resveratrol-Loaded Nanoparticles Based on Poly(epsilon-caprolactone) and Poly(d,l-lactic-co-glycolic acid)–Poly(ethylene glycol) Blend for Prostate Cancer Treatment

(2013) Vanna Sanna et al.   MOLECULAR PHARMACEUTICS

A Review of Dietary Prevention of Human Papillomavirus-Related Infection of the Cervix and Cervical Intraepithelial Neoplasia

(2013) Hui Jun Chih et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Methylated-(3′′)-Epigallocatechin Gallate Analog Suppresses Tumor Growth in Huh7 Hepatoma Cells Via Inhibition of Angiogenesis

(2013) Osamu Hashimoto et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Metabolomics Reveals Metabolic Targets and Biphasic Responses in Breast Cancer Cells Treated by Curcumin Alone and in Association with Docetaxel

(2013) Mathilde Bayet-Robert et al.   PLoS One

Difluorinated-Curcumin (CDF) Restores PTEN Expression in Colon Cancer Cells by Down-Regulating miR-21

(2013) Sanchita Roy et al.   PLoS One

Honokiol inhibits androgen receptor activity in prostate cancer cells

(2013) Eun-Ryeong Hahm et al.   PROSTATE

Ascorbic acid: Chemistry, biology and the treatment of cancer

(2012) Juan Du et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

Effect of 2-Month Controlled Green Tea Intervention on Lipoprotein Cholesterol, Glucose, and Hormone Levels in Healthy Postmenopausal Women

(2012) A. H. Wu et al.   Cancer Prevention Research

Controlled-release systemic delivery - a new concept in cancer chemoprevention

(2012) R. C. Gupta et al.   CARCINOGENESIS

Plumbagin Inhibits Breast Tumor Bone Metastasis and Osteolysis by Modulating the Tumor-Bone Microenvironment

(2012) Z. Li et al.   CURRENT MOLECULAR MEDICINE

Honokiol: A Novel Natural Agent for Cancer Prevention and Therapy

(2012) S. Arora et al.   CURRENT MOLECULAR MEDICINE

Targeting CSCs within the tumor microenvironment for cancer therapy: a potential role of mesenchymal stem cells

(2012) Bin Bao et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Resveratrol analog, HS-1793 enhance anti-tumor immunity by reducing the CD4+CD25+ regulatory T cells in FM3A tumor bearing mice

(2012) Min Ho Jeong et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Plumbagin inhibits tumorigenesis and angiogenesis of ovarian cancer cellsin vivo

(2012) Sutapa Sinha et al.   INTERNATIONAL JOURNAL OF CANCER

The novel resveratrol analogue HS-1793 induces apoptosis via the mitochondrial pathway in murine breast cancer cells

(2012) HYOUN-JI KIM et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Oxidative Stress Induced by Curcumin Promotes the Death of Cutaneous T-cell Lymphoma (HuT-78) by Disrupting the Function of Several Molecular Targets

(2012) M. A. Khan et al.   MOLECULAR CANCER THERAPEUTICS

An analogue of resveratrol HS-1793 exhibits anticancer activity against MCF-7 cells via inhibition of mitochondrial biogenesis gene expression

(2012) Seung Hun Jeong et al.   MOLECULES AND CELLS

Vitamins at physiological levels cause oxidation to the DNA nucleoside deoxyguanosine and to DNA--alone or in synergism with metals

(2012) T. Bergstrom et al.   MUTAGENESIS

Oral administration of copper to rats leads to increased lymphocyte cellular DNA degradation by dietary polyphenols: implications for a cancer preventive mechanism

(2011) Husain Y. Khan et al.   BIOMETALS

A metabolic perturbation by U0126 identifies a role for glutamine in resveratrol-induced cell death

(2011) Michael R. Freeman et al.   CANCER BIOLOGY & THERAPY

Curcumin Analogue CDF Inhibits Pancreatic Tumor Growth by Switching on Suppressor microRNAs and Attenuating EZH2 Expression

(2011) B. Bao et al.   CANCER RESEARCH

Hypoxia activates the hedgehog signaling pathway in a ligand-independent manner by upregulation of Smo transcription in pancreatic cancer

(2011) Hideya Onishi et al.   CANCER SCIENCE

Resveratrol prevents inflammation-dependent hepatic melanoma metastasis by inhibiting the secretion and effects of interleukin-18

(2011) Clarisa Salado et al.   Journal of Translational Medicine

Turmeric (Curcuma longa) inhibits inflammatory nuclear factor (NF)-κB and NF-κB-regulated gene products and induces death receptors leading to suppressed proliferation, induced chemosensitization, and suppressed osteoclastogenesis

(2011) Ji H. Kim et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Inflammation meets cancer, with NF-κB as the matchmaker

(2011) Yinon Ben-Neriah et al.   NATURE IMMUNOLOGY

Cancer Cell Signaling Pathways Targeted by Spice-Derived Nutraceuticals

(2011) Bokyung Sung et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Synthesis, structural andin vitrostudies of well-dispersed monomethoxy-poly(ethylene glycol)–honokiol conjugate micelles

(2010) Neng Qiu et al.   Biomedical Materials

Novel inhibitors of basal glucose transport as potential anticancer agents

(2010) Weihe Zhang et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Oxidative stress, inflammation, and cancer: How are they linked?

(2010) Simone Reuter et al.   FREE RADICAL BIOLOGY AND MEDICINE

Honokiol: an effective inhibitor of high-glucose-induced upregulation of inflammatory cytokine production in human renal mesangial cells

(2010) Jian-Ping Wu et al.   INFLAMMATION RESEARCH

Impact of Dietary Polyphenols on Carbohydrate Metabolism

(2010) Kati Hanhineva et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Co-Delivery Honokiol and Doxorubicin in MPEG-PLA Nanoparticles

(2010) Bilan Wang et al.   JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY

Nanochemoprevention: Sustained Release of Bioactive Food Components for Cancer Prevention

(2010) Imtiaz A. Siddiqui et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Nanochemoprevention by Bioactive Food Components: A Perspective

(2010) Imtiaz A. Siddiqui et al.   PHARMACEUTICAL RESEARCH

Difluorinated-Curcumin (CDF): A Novel Curcumin Analog is a Potent Inhibitor of Colon Cancer Stem-Like Cells

(2010) Shailender Singh Kanwar et al.   PHARMACEUTICAL RESEARCH

Resveratrol Mobilizes Endogenous Copper in Human Peripheral Lymphocytes Leading to Oxidative DNA Breakage: A Putative Mechanism for Chemoprevention of Cancer

(2010) S. M. Hadi et al.   PHARMACEUTICAL RESEARCH

Oxidative metabolism, ROS and NO under oxygen deprivation

(2010) Olga Blokhina et al.   PLANT PHYSIOLOGY AND BIOCHEMISTRY

Layer-by-Layer-Coated Gelatin Nanoparticles as a Vehicle for Delivery of Natural Polyphenols

(2009) Tatsiana G. Shutava et al.   ACS Nano

Proteasome inhibition in human breast cancer cells with high catechol-O-methyltransferase activity by green tea polyphenol EGCG analogs

(2009) Congde Huo et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Antitumor activity of novel fluoro-substituted (–)-epigallocatechin-3-gallate analogs

(2009) Huanjie Yang et al.   CANCER LETTERS

Introducing Nanochemoprevention as a Novel Approach for Cancer Control: Proof of Principle with Green Tea Polyphenol Epigallocatechin-3-Gallate

(2009) I. A. Siddiqui et al.   CANCER RESEARCH

Inhibition of cell proliferation by a resveratrol analog in human pancreatic and breast cancer cells

(2009) Young Bin Hong et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Fisetin, a natural flavonoid, targets chemoresistant human pancreatic cancer AsPC-1 cells through DR3-mediated inhibition of NF-κB

(2009) Imtiyaz Murtaza et al.   INTERNATIONAL JOURNAL OF CANCER

Poly(ɛ-caprolactone)–poly(ethylene glycol)–poly(ɛ-caprolactone) (PCL–PEG–PCL) nanoparticles for honokiol delivery in vitro

(2009) MaLing Gou et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Preparation of MPEG–PLA nanoparticle for honokiol delivery in vitro

(2009) XiuLing Zheng et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Plumbagin inhibits TPA-induced MMP-2 and u-PA expressions by reducing binding activities of NF-κB and AP-1 via ERK signaling pathway in A549 human lung cancer cells

(2009) Jiunn-Min Shieh et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Plumbagin induces cell death through a copper-redox cycle mechanism in human cancer cells

(2009) S. Nazeem et al.   MUTAGENESIS

Diet, cancer and public health nutrition

(2009) Marilyn Tseng   PUBLIC HEALTH NUTRITION

Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

(2009) M. G. Vander Heiden et al.   SCIENCE

Time-dependent intracellular trafficking of FITC-conjugated epigallocatechin-3-O-gallate in L-929 cells

(2008) Dong-Wook Han et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Resveratrol analog trans 3,4,5,4′-tetramethoxystilbene (DMU-212) mediates anti-tumor effects via mechanism different from that of resveratrol

(2008) Zengshuan Ma et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Elevated copper and oxidative stress in cancer cells as a target for cancer treatment

(2008) Anshul Gupte et al.   CANCER TREATMENT REVIEWS

The role of infections in autoimmune disease

(2008) A. M. Ercolini et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Is cancer a disease of abnormal cellular metabolism? New angles on an old idea

(2008) Ralph J Deberardinis   GENETICS IN MEDICINE

Prodrugs of Fluoro-Substituted Benzoates of EGC as Tumor Cellular Proteasome Inhibitors and Apoptosis Inducers

(2008) Zhiyong Yu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Plumbagin-induced apoptosis of human breast cancer cells is mediated by inactivation of NF-κB and Bcl-2

(2008) Aamir Ahmad et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Vitamin C stimulates or attenuates reactive oxygen and nitrogen species (ROS, RNS) production depending on cell state: Quantitative amperometric measurements of oxidative bursts at PLB-985 and RAW 264.7 cells at the single cell level

(2008) Christian Amatore et al.   JOURNAL OF ELECTROANALYTICAL CHEMISTRY

Cancer is a Preventable Disease that Requires Major Lifestyle Changes

(2008) Preetha Anand et al.   PHARMACEUTICAL RESEARCH