Increased Intracellular Reactive Oxygen Species Mediates the Anti-Cancer Effects of WZ35 via Activating Mitochondrial Apoptosis Pathway in Prostate Cancer Cells

Redox-assisted regulation of Ca2+homeostasis in the endoplasmic reticulum by disulfide reductase ERdj5

(2016) Ryo Ushioda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Blockage of ROS and NF-κB-mediated inflammation by a new chalcone L6H9 protects cardiomyocytes from hyperglycemia-induced injuries

(2015) Peng Zhong et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Sequencing current therapies in the treatment of metastatic prostate cancer

(2015) Loana B. Valenca et al.   CANCER TREATMENT REVIEWS

Low-pH-induced apoptosis: role of endoplasmic reticulum stress-induced calcium permeability and mitochondria-dependent signaling

(2015) Vishal Sharma et al.   CELL STRESS & CHAPERONES

Curcumin protects hearts from FFA-induced injury by activating Nrf2 and inactivating NF-κB both in vitro and in vivo

(2015) Chunlai Zeng et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

ROS generation mediates the anti-cancer effects of WZ35 via activating JNK and ER stress apoptotic pathways in gastric cancer

(2015) Peng Zou et al.   Oncotarget

Empirical estimates of prostate cancer overdiagnosis by age and prostate-specific antigen

(2014) Andrew J Vickers et al.   BMC Medicine

The Disturbances of Endoplasmic Reticulum Calcium Homeostasis Caused by Increased Intracellular Reactive Oxygen Species Contributes to Fragmentation in Aged Porcine Oocytes1

(2013) Da-Wei Tang et al.   BIOLOGY OF REPRODUCTION

Evaluation of a curcumin analog as an anti-cancer agent inducing ER stress-mediated apoptosis in non-small cell lung cancer cells

(2013) Zhiguo Liu et al.   BMC CANCER

Condurango glycoside-rich components stimulate DNA damage-induced cell cycle arrest and ROS-mediated caspase-3 dependent apoptosis through inhibition of cell-proliferation in lung cancer, in vitro and in vivo

(2013) Sourav Sikdar et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Synthesis and biological evaluation of allylated and prenylated mono-carbonyl analogs of curcumin as anti-inflammatory agents

(2013) Zhiguo Liu et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Arctigenin, a dietary phytoestrogen, induces apoptosis of estrogen receptor-negative breast cancer cells through the ROS/p38 MAPK pathway and epigenetic regulation

(2013) Chia-Jung Hsieh et al.   FREE RADICAL BIOLOGY AND MEDICINE

B19, a Novel Monocarbonyl Analogue of Curcumin, Induces Human Ovarian Cancer Cell Apoptosis via Activation of Endoplasmic Reticulum Stress and the Autophagy Signaling Pathway

(2013) Wanglei Qu et al.   International Journal of Biological Sciences

Targeting mitochondrial reactive oxygen species as novel therapy for inflammatory diseases and cancers

(2013) Xinyuan Li et al.   Journal of Hematology & Oncology

Zinc oxide nanoparticles induce oxidative DNA damage and ROS-triggered mitochondria mediated apoptosis in human liver cells (HepG2)

(2012) Vyom Sharma et al.   APOPTOSIS

High glucose-induced Ca2+ overload and oxidative stress contribute to apoptosis of cardiac cells through mitochondrial dependent and independent pathways

(2012) Sandeep Kumar et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

T63, a new 4-arylidene curcumin analogue, induces cell cycle arrest and apoptosis through activation of the reactive oxygen species–FOXO3a pathway in lung cancer cells

(2012) Hao Liu et al.   FREE RADICAL BIOLOGY AND MEDICINE

Interplay of reactive oxygen species, intracellular Ca2+and mitochondrial homeostasis in the apoptosis of prostate cancer cells by deoxypodophyllotoxin

(2012) Kwang-Youn Kim et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Retigeric Acid B Exhibits Antitumor Activity through Suppression of Nuclear Factor-κB Signaling in Prostate Cancer Cells in Vitro and in Vivo

(2012) Yong-Qing Liu et al.   PLoS One

Salinomycin-induced apoptosis of human prostate cancer cells due to accumulated reactive oxygen species and mitochondrial membrane depolarization

(2011) Kwang-Youn Kim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

ROS-Ca2+ is associated with mitochondria permeability transition pore involved in surfactin-induced MCF-7 cells apoptosis

(2011) Xiao-hong Cao et al.   CHEMICO-BIOLOGICAL INTERACTIONS

A synthetic compound, 1,5-bis(2-methoxyphenyl)penta- 1,4-dien-3-one (B63), induces apoptosis and activates endoplasmic reticulum stress in non-small cell lung cancer cells

(2011) Jian Xiao et al.   INTERNATIONAL JOURNAL OF CANCER

Evaluation and Discovery of Novel Synthetic Chalcone Derivatives as Anti-Inflammatory Agents

(2011) Jianzhang Wu et al.   JOURNAL OF MEDICINAL CHEMISTRY

Growth inhibitory effect and Chk1-dependent signaling involved in G2/M arrest on human gastric cancer cells induced by diallyl disulfide

(2010) H. Ling et al.   BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH

Oleanane triterpenoid CDDO-Me inhibits growth and induces apoptosis in prostate cancer cells through a ROS-dependent mechanism

(2009) Dorrah Deeb et al.   BIOCHEMICAL PHARMACOLOGY

Gallic acid, a major component of Toona sinensis leaf extracts, contains a ROS-mediated anti-cancer activity in human prostate cancer cells

(2009) Huei-Mei Chen et al.   CANCER LETTERS

The role of endoplasmic reticulum in cadmium-induced mesangial cell apoptosis

(2009) Sheng-Hao Wang et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?

(2009) Dunyaporn Trachootham et al.   NATURE REVIEWS DRUG DISCOVERY

Oxidative Stress Is Inherent in Prostate Cancer Cells and Is Required for Aggressive Phenotype

(2008) B. Kumar et al.   CANCER RESEARCH

Intraosseous injection of RM1 murine prostate cancer cells promotes rapid osteolysis and periosteal bone deposition

(2008) N. Patrick McCabe et al.   CLINICAL & EXPERIMENTAL METASTASIS

A Phase I Study of the Pan Bcl-2 Family Inhibitor Obatoclax Mesylate in Patients with Advanced Hematologic Malignancies

(2008) A. D. Schimmer et al.   CLINICAL CANCER RESEARCH

Calcium and apoptosis: ER-mitochondria Ca2+ transfer in the control of apoptosis

(2008) P Pinton et al.   ONCOGENE