Exendin-4 Ameliorates Motor Neuron Degeneration in Cellular and Animal Models of Amyotrophic Lateral Sclerosis

Glucagon-like Peptide-1 improves proliferation and differentiation of endothelial progenitor cells via upregulating VEGF generation

(2013) Xie Xiao-Yun et al.   MEDICAL SCIENCE MONITOR

Neuroprotective effect of the glucagon-like peptide-1 receptor agonist, synthetic exendin-4, in streptozotocin-induced diabetic rats

(2011) Wei Jing Liu et al.   BRITISH JOURNAL OF PHARMACOLOGY

Targeting TNF-Alpha to Elucidate and Ameliorate Neuroinflammation in Neurodegenerative Diseases

(2011) Kathryn A. Frankola et al.   CNS & Neurological Disorders-Drug Targets

Neuroprotective properties of GLP-1: theoretical and practical applications

(2011) Jens Juul Holst et al.   CURRENT MEDICAL RESEARCH AND OPINION

Glucagon-like Peptide–1 Analogues for Type 2 Diabetes Mellitus

(2011) Baptist Gallwitz   DRUGS

Emerging drugs for amyotrophic lateral sclerosis

(2011) Ali Aamer Habib et al.   EXPERT OPINION ON EMERGING DRUGS

Exendin-4, a Glucagon-Like Peptide-1 Receptor Agonist, Provides Neuroprotection in Mice Transient Focal Cerebral Ischemia

(2011) Shinichiro Teramoto et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Dysregulation of the ALS-associated gene TDP-43 leads to neuronal death and degeneration in mice

(2011) Lionel M. Igaz et al.   JOURNAL OF CLINICAL INVESTIGATION

The Diabetes Drug Liraglutide Prevents Degenerative Processes in a Mouse Model of Alzheimer's Disease

(2011) P. L. McClean et al.   JOURNAL OF NEUROSCIENCE

In Vivo Imaging Reveals Distinct Inflammatory Activity of CNS Microglia versus PNS Macrophages in a Mouse Model for ALS

(2011) Payam Dibaj et al.   PLoS One

GFAP in health and disease

(2011) J. Middeldorp et al.   PROGRESS IN NEUROBIOLOGY

Hyperosmolar hyperglycemic state in advanced amyotrophic lateral sclerosis

(2010) Toshio Shimizu et al.   Amyotrophic Lateral Sclerosis

Impaired glucose tolerance in patients with amyotrophic lateral sclerosis

(2010) Pierre-Francois Pradat et al.   Amyotrophic Lateral Sclerosis

Current Nervous System Related Drug Targets for the Treatment of Amyotrophic Lateral Sclerosis

(2010) Aaron C. Pawlyk et al.   CURRENT PHARMACEUTICAL DESIGN

The glucagon-like peptide 1 receptor agonist exendin-4 improves reference memory performance and decreases immobility in the forced swim test

(2010) Ruben Isacson et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Motor neuron–immune interactions: the vicious circle of ALS

(2010) Ana G. Barbeito et al.   JOURNAL OF NEURAL TRANSMISSION

Wild-type and mutant SOD1 share an aberrant conformation and a common pathogenic pathway in ALS

(2010) Daryl A Bosco et al.   NATURE NEUROSCIENCE

TDP-43-Based Animal Models of Neurodegeneration: New Insights into ALS Pathology and Pathophysiology

(2010) Iga Wegorzewska et al.   Neurodegenerative Diseases

Functional neural stem cell isolation from brains of adult mutant SOD1 (SOD1G93A) transgenic amyotrophic lateral sclerosis (ALS) mice

(2010) Jae Chul Lee et al.   NEUROLOGICAL RESEARCH

Glucagon-like peptide-1 protects NSC-34 motor neurons against glucosamine through Epac-mediated glucose uptake enhancement

(2010) Jung-Geun Lim et al.   NEUROSCIENCE LETTERS

Impairment of synaptic plasticity and memory formation in GLP-1 receptor KO mice: Interaction between type 2 diabetes and Alzheimer's disease

(2009) Talib Abbas et al.   BEHAVIOURAL BRAIN RESEARCH

Determination of high-affinity choline uptake (HACU) and choline acetyltransferase (ChAT) activity in the same population of cultured cells

(2009) Balmiki Ray et al.   BRAIN RESEARCH

Exendin-4 protects dopaminergic neurons by inhibition of microglial activation and matrix metalloproteinase-3 expression in an animal model of Parkinson's disease

(2009) Sehee Kim et al.   JOURNAL OF ENDOCRINOLOGY

Microglia in ALS: The Good, The Bad, and The Resting

(2009) Jenny S. Henkel et al.   Journal of Neuroimmune Pharmacology

Pharmacological Characterization of Human Incretin Receptor Missense Variants

(2009) J.-P. Fortin et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Incretin-based therapies for type 2 diabetes mellitus

(2009) Julie A. Lovshin et al.   Nature Reviews Endocrinology

Decline in Daily Running Distance Presages Disease Onset in a Mouse Model of ALS

(2009) Daniel A. Bruestle et al.   NEUROMOLECULAR MEDICINE

Receptors for the incretin glucagon-like peptide-1 are expressed on neurons in the central nervous system

(2009) Alison Hamilton et al.   NEUROREPORT

TDP-43 mutant transgenic mice develop features of ALS and frontotemporal lobar degeneration

(2009) I. Wegorzewska et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

GLP-1 receptor stimulation preserves primary cortical and dopaminergic neurons in cellular and rodent models of stroke and Parkinsonism

(2009) Y. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Exendin-4 Improves Glycemic Control, Ameliorates Brain and Pancreatic Pathologies, and Extends Survival in a Mouse Model of Huntington's Disease

(2008) B. Martin et al.   DIABETES

Glucagon-like peptide 1 receptor stimulation by exendin-4 reverses key deficits in distinct rodent models of Parkinson's disease

(2008) Alexander Harkavyi et al.   Journal of Neuroinflammation

Amyotrophic Lateral Sclerosis: From Current Developments in the Laboratory to Clinical Implications

(2007) Mauro Cozzolino et al.   ANTIOXIDANTS & REDOX SIGNALING

Peptide hormone exendin-4 stimulates subventricular zone neurogenesis in the adult rodent brain and induces recovery in an animal model of parkinson's disease

(2007) Göran Bertilsson et al.   JOURNAL OF NEUROSCIENCE RESEARCH