Neuroprotective Effect of 6-Paradol in Focal Cerebral Ischemia Involves the Attenuation of Neuroinflammatory Responses in Activated Microglia

6-Shogaol, an active constituent of ginger, attenuates neuroinflammation and cognitive deficits in animal models of dementia

(2014) Minho Moon et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Synthesis of Analogues of Gingerol and Shogaol, the Active Pungent Principles from the Rhizomes of Zingiber officinale and Evaluation of Their Anti-Platelet Aggregation Effects

(2014) Hung-Cheng Shih et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Relationship between the Acyl Chain Length of Paradol Analogues and Their Antiobesity Activity following Oral Ingestion

(2014) Akinori Haratake et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Herbal Medicines for Ischemic Stroke: Combating Inflammation as Therapeutic Targets

(2014) Yong Gu et al.   Journal of Neuroimmune Pharmacology

Chemopreventive and antioxidant efficacy of (6)-paradol in 7, 12-dimethylbenz(a)anthracene induced hamster buccal pouch carcinogenesis

(2014) Kathiresan Suresh et al.   Pharmacological Reports

6-Shogaol, an active compound of ginger, protects dopaminergic neurons in Parkinson's disease models via anti-neuroinflammation

(2013) Gunhyuk Park et al.   ACTA PHARMACOLOGICA SINICA

Proliferation of parenchymal microglia is the main source of microgliosis after ischaemic stroke

(2013) Ting Li et al.   BRAIN

[6]-Shogaol inhibits growth and induces apoptosis of non-small cell lung cancer cells by directly regulating Akt1/2

(2013) Myoung Ok Kim et al.   CARCINOGENESIS

Possible Therapeutic Uses of Salvia triloba and Piper nigrum in Alzheimer's Disease–Induced Rats

(2013) Hanaa H. Ahmed et al.   JOURNAL OF MEDICINAL FOOD

Licorice-derived dehydroglyasperin C increases MKP-1 expression and suppresses inflammation-mediated neurodegeneration

(2013) Jaekyoon Kim et al.   NEUROCHEMISTRY INTERNATIONAL

Microglia are the major source of TNF-α and TGF-β1 in postnatal glial cultures; regulation by cytokines, lipopolysaccharide, and vitronectin

(2013) Jennifer V. Welser-Alves et al.   NEUROCHEMISTRY INTERNATIONAL

Protective Effects of Ginger Root Extract on Alzheimer Disease-Induced Behavioral Dysfunction in Rats

(2013) Gao-feng Zeng et al.   REJUVENATION RESEARCH

An Impression on Current Developments in the Technology, Chemistry, and Biological Activities of Ginger (Zingiber officinaleRoscoe)

(2012) I. Rahath Kubra et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Neuroinflammation: A Common Pathway in CNS Diseases as Mediated at the Blood-Brain Barrier

(2012) Michelle A. Erickson et al.   NEUROIMMUNOMODULATION

6-Shogaol, a ginger product, modulates neuroinflammation: A new approach to neuroprotection

(2012) Sang Keun Ha et al.   NEUROPHARMACOLOGY

Ginger and its Health Claims: Molecular Aspects

(2011) Masood Sadiq Butt et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

A modified formulation of Chinese traditional medicine improves memory impairment and reduces Aβ level in the Tg-APPswe/PS1dE9 mouse model of Alzheimer's disease

(2011) Songhee Jeon et al.   JOURNAL OF ETHNOPHARMACOLOGY

Neuroprotection by Spice-Derived Nutraceuticals: You Are What You Eat!

(2011) Ramaswamy Kannappan et al.   MOLECULAR NEUROBIOLOGY

Clinical Review and Treatment of Select Adverse Effects of Dopamine Receptor Agonists in Parkinsonʼs Disease

(2010) Lindy D. Wood   DRUGS & AGING

6-Shogaol is more effective than 6-gingerol and curcumin in inhibiting 12-O-tetradecanoylphorbol 13-acetate-induced tumor promotion in mice

(2010) Hou Wu et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Revisiting dietary antioxidants, neurodegeneration and dementia

(2010) Lucinda Craggs et al.   NEUROREPORT

Microglia: biology and pathology

(2009) Manuel B. Graeber et al.   ACTA NEUROPATHOLOGICA

Increased Growth Inhibitory Effects on Human Cancer Cells and Anti-inflammatory Potency of Shogaols from Zingiber officinale Relative to Gingerols

(2009) Shengmin Sang et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Comparative antioxidant and anti-inflammatory effects of [6]-gingerol, [8]-gingerol, [10]-gingerol and [6]-shogaol

(2009) Swarnalatha Dugasani et al.   JOURNAL OF ETHNOPHARMACOLOGY

Inflammatory mechanisms in ischemic stroke: therapeutic approaches

(2009) Shaheen E Lakhan et al.   Journal of Translational Medicine

NCX1 Expression and Functional Activity Increase in Microglia Invading the Infarct Core

(2009) Francesca Boscia et al.   STROKE

Pharmacokinetics of 6-Gingerol, 8-Gingerol, 10-Gingerol, and 6-Shogaol and Conjugate Metabolites in Healthy Human Subjects

(2008) S. M. Zick et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

TNF signaling inhibition in the CNS: implications for normal brain function and neurodegenerative disease

(2008) Melissa K McCoy et al.   Journal of Neuroinflammation

Mechanisms of ischemic brain damage

(2008) Kristian P. Doyle et al.   NEUROPHARMACOLOGY

Some phytochemical, pharmacological and toxicological properties of ginger (Zingiber officinale Roscoe): A review of recent research

(2007) Badreldin H. Ali et al.   FOOD AND CHEMICAL TOXICOLOGY