Deficit, but Not Nondeficit, Schizophrenia Is Characterized by Mucosa-Associated Activation of the Tryptophan Catabolite (TRYCAT) Pathway with Highly Specific Increases in IgA Responses Directed to Picolinic, Xanthurenic, and Quinolinic Acid
Published 2017 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Deficit, but Not Nondeficit, Schizophrenia Is Characterized by Mucosa-Associated Activation of the Tryptophan Catabolite (TRYCAT) Pathway with Highly Specific Increases in IgA Responses Directed to Picolinic, Xanthurenic, and Quinolinic Acid
Authors
Keywords
Schizophrenia, Immune, Inflammation, Cytokines, Oxidative stress, IDO, Kynurenine
Journal
MOLECULAR NEUROBIOLOGY
Volume 55, Issue 2, Pages 1524-1536
Publisher
Springer Nature
Online
2017-02-08
DOI
10.1007/s12035-017-0417-6
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Reversal of schizophrenia-like symptoms and immune alterations in mice by immunomodulatory drugs
- (2017) Tatiane da Silva Araújo et al. JOURNAL OF PSYCHIATRIC RESEARCH
- Deficit Schizophrenia Is Characterized by Defects in IgM-Mediated Responses to Tryptophan Catabolites (TRYCATs): a Paradigm Shift Towards Defects in Natural Self-Regulatory Immune Responses Coupled with Mucosa-Derived TRYCAT Pathway Activation
- (2017) Buranee Kanchanatawan et al. MOLECULAR NEUROBIOLOGY
- The Many Neuroprogressive Actions of Tryptophan Catabolites (TRYCATs) that may be Associated with the Pathophysiology of Neuro-Immune Disorders
- (2016) Gerwyn Morris et al. CURRENT PHARMACEUTICAL DESIGN
- A meta-analysis of blood cytokine network alterations in psychiatric patients: comparisons between schizophrenia, bipolar disorder and depression
- (2016) D R Goldsmith et al. MOLECULAR PSYCHIATRY
- A review of vulnerability and risks for schizophrenia: Beyond the two hit hypothesis
- (2016) Justin Davis et al. NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
- Kynurenine and Tryptophan Levels in Patients With Schizophrenia and Elevated Antigliadin Immunoglobulin G Antibodies
- (2016) Olaoluwa Okusaga et al. PSYCHOSOMATIC MEDICINE
- Body image dissatisfaction in pregnant and non-pregnant females is strongly predicted by immune activation and mucosa-derived activation of the tryptophan catabolite (TRYCAT) pathway
- (2016) Chutima Roomruangwong et al. WORLD JOURNAL OF BIOLOGICAL PSYCHIATRY
- Anthranilic acids from isatin: an efficient, versatile and environmentally friendly method
- (2015) GABRIEL F. RIO et al. ANAIS DA ACADEMIA BRASILEIRA DE CIENCIAS
- Neurocognitive impairment in the deficit subtype of schizophrenia
- (2015) Gagan Fervaha et al. EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE
- Oxidative stress in drug naïve first episode psychosis and antioxidant effects of risperidone
- (2015) Cristiano Noto et al. JOURNAL OF PSYCHIATRIC RESEARCH
- Effects of depression on the cytokine profile in drug naïve first-episode psychosis
- (2015) Cristiano Noto et al. SCHIZOPHRENIA RESEARCH
- Gastroenterology Issues in Schizophrenia: Why the Gut Matters
- (2015) Emily G. Severance et al. Current Psychiatry Reports
- Xanthurenic Acid Activates mGlu2/3 Metabotropic Glutamate Receptors and is a Potential Trait Marker for Schizophrenia
- (2015) Francesco Fazio et al. Scientific Reports
- Deficit schizophrenia: an update
- (2015) BRIAN KIRKPATRICK et al. World Psychiatry
- Neuroprogression in schizophrenia: Pathways underpinning clinical staging and therapeutic corollaries
- (2014) Justin Davis et al. AUSTRALIAN AND NEW ZEALAND JOURNAL OF PSYCHIATRY
- Cytokine function in medication-naive first episode psychosis: A systematic review and meta-analysis
- (2014) Rachel Upthegrove et al. SCHIZOPHRENIA RESEARCH
- Modulation of Hippocampal Synaptic Transmission by the Kynurenine Pathway Member Xanthurenic Acid and Other VGLUT Inhibitors
- (2013) S A Neale et al. NEUROPSYCHOPHARMACOLOGY
- Depression and sickness behavior are Janus-faced responses to shared inflammatory pathways
- (2012) Michael Maes et al. BMC Medicine
- Xanthurenic Acid Binds to Neuronal G-Protein-Coupled Receptors That Secondarily Activate Cationic Channels in the Cell Line NCB-20
- (2012) Omar Taleb et al. PLoS One
- Schizophrenia is primed for an increased expression of depression through activation of immuno-inflammatory, oxidative and nitrosative stress, and tryptophan catabolite pathways
- (2012) George Anderson et al. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
- Schizophrenia: Linking prenatal infection to cytokines, the tryptophan catabolite (TRYCAT) pathway, NMDA receptor hypofunction, neurodevelopment and neuroprogression
- (2012) George Anderson et al. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
- On the antioxidant properties of kynurenic acid: Free radical scavenging activity and inhibition of oxidative stress
- (2011) R. Lugo-Huitrón et al. NEUROTOXICOLOGY AND TERATOLOGY
- Acute elevations of brain kynurenic acid impair cognitive flexibility: normalization by the alpha7 positive modulator galantamine
- (2011) Kathleen S. Alexander et al. PSYCHOPHARMACOLOGY
- Aging-associated increase in indoleamine 2,3-dioxygenase (IDO) activity appears to be unrelated to the transcription of the IDO1 or IDO2 genes in peripheral blood mononuclear cells
- (2011) Saara Marttila et al. Immunity & Ageing
- The new ‘5-HT’ hypothesis of depression: Cell-mediated immune activation induces indoleamine 2,3-dioxygenase, which leads to lower plasma tryptophan and an increased synthesis of detrimental tryptophan catabolites (TRYCATs), both of which contribute to the onset of depression
- (2010) M. Maes et al. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
- Decreased plasma tryptophan and tryptophan/large neutral amino acid ratio in patients with neuroleptic-resistant schizophrenia: Relationship to plasma cortisol concentration
- (2010) Myung Lee et al. PSYCHIATRY RESEARCH
- Impaired Kynurenine Pathway Metabolism in The Prefrontal Cortex of Individuals With Schizophrenia
- (2010) K. V. Sathyasaikumar et al. SCHIZOPHRENIA BULLETIN
- Increased Levels of Kynurenine and Kynurenic Acid in the CSF of Patients With Schizophrenia
- (2010) K. R. Linderholm et al. SCHIZOPHRENIA BULLETIN
- Indoleamine 2,3-dioxygenase in intestinal immunity and inflammation
- (2009) Bobby J. Cherayil INFLAMMATORY BOWEL DISEASES
- Constitutive Expression of IDO by Dendritic Cells of Mesenteric Lymph Nodes: Functional Involvement of the CTLA-4/B7 and CCL22/CCR4 Interactions
- (2009) T. Onodera et al. JOURNAL OF IMMUNOLOGY
- Relationship of Cognition and Psychopathology to Functional Impairment in Schizophrenia
- (2008) Somaia Mohamed et al. AMERICAN JOURNAL OF PSYCHIATRY
- Xanthurenic acid distribution, transport, accumulation and release in the rat brain
- (2008) Serge Gobaille et al. JOURNAL OF NEUROCHEMISTRY
- Kynurenine pathway in psychosis: evidence of increased tryptophan degradation
- (2008) S Barry et al. JOURNAL OF PSYCHOPHARMACOLOGY
- Specific inhibition of kynurenate synthesis enhances extracellular dopamine levels in the rodent striatum
- (2008) L. Amori et al. NEUROSCIENCE
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExplorePublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More