Deficit Schizophrenia Is Characterized by Defects in IgM-Mediated Responses to Tryptophan Catabolites (TRYCATs): a Paradigm Shift Towards Defects in Natural Self-Regulatory Immune Responses Coupled with Mucosa-Derived TRYCAT Pathway Activation

Memantine and Kynurenic Acid: Current Neuropharmacological Aspects

(2016) Zsófia Majláth et al.   Current Neuropharmacology

A meta-analysis of blood cytokine network alterations in psychiatric patients: comparisons between schizophrenia, bipolar disorder and depression

(2016) D R Goldsmith et al.   MOLECULAR PSYCHIATRY

A review of vulnerability and risks for schizophrenia: Beyond the two hit hypothesis

(2016) Justin Davis et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Body image dissatisfaction in pregnant and non-pregnant females is strongly predicted by immune activation and mucosa-derived activation of the tryptophan catabolite (TRYCAT) pathway

(2016) Chutima Roomruangwong et al.   WORLD JOURNAL OF BIOLOGICAL PSYCHIATRY

Anthranilic acids from isatin: an efficient, versatile and environmentally friendly method

(2015) GABRIEL F. RIO et al.   ANAIS DA ACADEMIA BRASILEIRA DE CIENCIAS

Absence of aryl hydrocarbon receptors increases endogenous kynurenic acid levels and protects mouse brain against excitotoxic insult and oxidative stress

(2015) Lucia García-Lara et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Effects of depression on the cytokine profile in drug naïve first-episode psychosis

(2015) Cristiano Noto et al.   SCHIZOPHRENIA RESEARCH

Gastroenterology Issues in Schizophrenia: Why the Gut Matters

(2015) Emily G. Severance et al.   Current Psychiatry Reports

Deficit schizophrenia: an update

(2015) BRIAN KIRKPATRICK et al.   World Psychiatry

Neuroprogression in schizophrenia: Pathways underpinning clinical staging and therapeutic corollaries

(2014) Justin Davis et al.   AUSTRALIAN AND NEW ZEALAND JOURNAL OF PSYCHIATRY

Local Melatonin Regulates Inflammation Resolution: A Common Factor in Neurodegenerative, Psychiatric and Systemic Inflammatory Disorders

(2014) George Anderson et al.   CNS & Neurological Disorders-Drug Targets

Safety and clinical effects of EVP-6124 in subjects with Alzheimer's disease currently or previously receiving an acetylcholinesterase inhibitor medication

(2014) William James Deardorff et al.   Expert Review of Neurotherapeutics

Are Negative Symptoms Dimensional or Categorical? Detection and Validation of Deficit Schizophrenia With Taxometric and Latent Variable Mixture Models

(2014) Anthony O. Ahmed et al.   SCHIZOPHRENIA BULLETIN

Meta-Analysis of Oxidative Stress in Schizophrenia

(2013) Joshua Flatow et al.   BIOLOGICAL PSYCHIATRY

The effect of transient increases in kynurenic acid and quinolinic acid levels early in life on behavior in adulthood: Implications for schizophrenia

(2013) Hannah F. Iaccarino et al.   SCHIZOPHRENIA RESEARCH

In depression, bacterial translocation may drive inflammatory responses, oxidative and nitrosative stress (O&NS), and autoimmune responses directed against O&NS-damaged neoepitopes

(2012) M. Maes et al.   ACTA PSYCHIATRICA SCANDINAVICA

Depression and sickness behavior are Janus-faced responses to shared inflammatory pathways

(2012) Michael Maes et al.   BMC Medicine

Increased autoimmune responses against auto-epitopes modified by oxidative and nitrosative damage in depression: Implications for the pathways to chronic depression and neuroprogression

(2012) Michael Maes et al.   JOURNAL OF AFFECTIVE DISORDERS

Melatonin decreases duodenal epithelial paracellular permeability via a nicotinic receptor-dependent pathway in rats in vivo

(2012) Anna Sommansson et al.   JOURNAL OF PINEAL RESEARCH

Elevated serum level of type-2 cytokine and low IL-17 in first episode psychosis and schizophrenia in relapse

(2012) Milica Borovcanin et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Schizophrenia: Linking prenatal infection to cytokines, the tryptophan catabolite (TRYCAT) pathway, NMDA receptor hypofunction, neurodevelopment and neuroprogression

(2012) George Anderson et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Cortical structural abnormalities in deficit versus nondeficit schizophrenia

(2012) Bernard A. Fischer et al.   SCHIZOPHRENIA RESEARCH

On the antioxidant properties of kynurenic acid: Free radical scavenging activity and inhibition of oxidative stress

(2011) R. Lugo-Huitrón et al.   NEUROTOXICOLOGY AND TERATOLOGY

Administration of kynurenine during adolescence, but not during adulthood, impairs social behavior in rats

(2011) Katelyn V. Trecartin et al.   SCHIZOPHRENIA RESEARCH

Is modulation of nicotinic acetylcholine receptors by melatonin relevant for therapy with cholinergic drugs?

(2010) Regina P. Markus et al.   PHARMACOLOGY & THERAPEUTICS

The new ‘5-HT’ hypothesis of depression: Cell-mediated immune activation induces indoleamine 2,3-dioxygenase, which leads to lower plasma tryptophan and an increased synthesis of detrimental tryptophan catabolites (TRYCATs), both of which contribute to the onset of depression

(2010) M. Maes et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Decreased plasma tryptophan and tryptophan/large neutral amino acid ratio in patients with neuroleptic-resistant schizophrenia: Relationship to plasma cortisol concentration

(2010) Myung Lee et al.   PSYCHIATRY RESEARCH

Natural antibodies, intravenous immunoglobulin and their role in autoimmunity, cancer and inflammation

(2009) R. Schwartz-Albiez et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Indoleamine 2,3-dioxygenase in intestinal immunity and inflammation

(2009) Bobby J. Cherayil   INFLAMMATORY BOWEL DISEASES

Constitutive Expression of IDO by Dendritic Cells of Mesenteric Lymph Nodes: Functional Involvement of the CTLA-4/B7 and CCL22/CCR4 Interactions

(2009) T. Onodera et al.   JOURNAL OF IMMUNOLOGY

Mechanism for Quinolinic Acid Cytotoxicity in Human Astrocytes and Neurons

(2009) Nady Braidy et al.   NEUROTOXICITY RESEARCH