Acute elevations of brain kynurenic acid impair cognitive flexibility: normalization by the alpha7 positive modulator galantamine

Downregulated Kynurenine 3-Monooxygenase Gene Expression and Enzyme Activity in Schizophrenia and Genetic Association With Schizophrenia Endophenotypes

(2011) Ikwunga Wonodi   ARCHIVES OF GENERAL PSYCHIATRY

Fluctuations in Endogenous Kynurenic Acid Control Hippocampal Glutamate and Memory

(2011) Ana Pocivavsek et al.   NEUROPSYCHOPHARMACOLOGY

Blockade of NMDA GluN2B receptors selectively impairs behavioral flexibility but not initial discrimination learning

(2011) Gemma L. Dalton et al.   PSYCHOPHARMACOLOGY

Alterations in Metabotropic Glutamate Receptor 1α and Regulator of G Protein Signaling 4 in the Prefrontal Cortex in Schizophrenia

(2010) David W. Volk et al.   AMERICAN JOURNAL OF PSYCHIATRY

Learning and cognitive flexibility: frontostriatal function and monoaminergic modulation

(2010) Angie A Kehagia et al.   CURRENT OPINION IN NEUROBIOLOGY

Activation of type 5 metabotropic glutamate receptors attenuates deficits in cognitive flexibility induced by NMDA receptor blockade

(2010) Mark R. Stefani et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

More Is Less: A Disinhibited Prefrontal Cortex Impairs Cognitive Flexibility

(2010) A. J. Gruber et al.   JOURNAL OF NEUROSCIENCE

Differential Contributions of the Primate Ventrolateral Prefrontal and Orbitofrontal Cortex to Serial Reversal Learning

(2010) R. Rygula et al.   JOURNAL OF NEUROSCIENCE

Cortical kynurenic acid bi-directionally modulates prefrontal glutamate levels as assessed by microdialysis and rapid electrochemistry

(2010) Å. Konradsson-Geuken et al.   NEUROSCIENCE

Assessing cognitive function in clinical trials of schizophrenia

(2010) Jennifer H. Barnett et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Cortical Kynurenine Pathway Metabolism: A Novel Target for Cognitive Enhancement in Schizophrenia

(2010) I. Wonodi et al.   SCHIZOPHRENIA BULLETIN

Galantamine augmentation of long-acting injectable risperidone for cognitive impairments in chronic schizophrenia

(2010) Jean-Pierre Lindenmayer et al.   SCHIZOPHRENIA RESEARCH

Alterations of Cortical GABA Neurons and Network Oscillations in Schizophrenia

(2010) Guillermo Gonzalez-Burgos et al.   Current Psychiatry Reports

The Neuropsychopharmacology of Fronto-Executive Function: Monoaminergic Modulation

(2009) T.W. Robbins et al.   Annual Review of Neuroscience

L-kynurenine treatment alters contextual fear conditioning and context discrimination but not cue-specific fear conditioning

(2009) Amy C. Chess et al.   BEHAVIOURAL BRAIN RESEARCH

Functional and Dysfunctional Synaptic Plasticity in Prefrontal Cortex: Roles in Psychiatric Disorders

(2009) Yukiori Goto et al.   BIOLOGICAL PSYCHIATRY

Astrocyte-derived kynurenic acid modulates basal and evoked cortical acetylcholine release

(2009) A. Zmarowski et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

The Astrocyte-Derived α7 Nicotinic Receptor Antagonist Kynurenic Acid Controls Extracellular Glutamate Levels in the Prefrontal Cortex

(2009) Hui-Qiu Wu et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Chronic infusion of PCP via osmotic mini-pumps: A new rodent model of cognitive deficit in schizophrenia characterized by impaired attentional set-shifting (ID/ED) performance

(2009) Christian Spang Pedersen et al.   JOURNAL OF NEUROSCIENCE METHODS

Ventral Striatal Dopamine Modulation of Different Forms of Behavioral Flexibility

(2009) Desirae M Haluk et al.   NEUROPSYCHOPHARMACOLOGY

Second-by-second analysis of alpha 7 nicotine receptor regulation of glutamate release in the prefrontal cortex of awake rats

(2009) Åsa Konradsson-Geuken et al.   SYNAPSE

Cholinergic Mediation of Attention

(2008) Vinay Parikh et al.   Annals of the New York Academy of Sciences

Neural circuits subserving behavioral flexibility and their relevance to schizophrenia

(2008) Stan B. Floresco et al.   BEHAVIOURAL BRAIN RESEARCH

Interaction of N-methyl-D-aspartate and group 5 metabotropic glutamate receptors on behavioral flexibility using a novel operant set-shift paradigm

(2008) Justin M. Darrah et al.   BEHAVIOURAL PHARMACOLOGY

N-Methyl-D-Aspartate Receptor and Calbindin-Containing Neurons in the Anterior Cingulate Cortex in Schizophrenia and Bipolar Disorder

(2008) Tsung-Ung W. Woo et al.   BIOLOGICAL PSYCHIATRY

Executive Functioning Component Mechanisms and Schizophrenia

(2008) John G. Kerns et al.   BIOLOGICAL PSYCHIATRY

Decreased cortical muscarinic receptors define a subgroup of subjects with schizophrenia

(2008) E Scarr et al.   MOLECULAR PSYCHIATRY

Noradrenergic, but not cholinergic, deafferentation of prefrontal cortex impairs attentional set-shifting

(2008) J. McGaughy et al.   NEUROSCIENCE

CNTRICS Final Task Selection: Control of Attention

(2008) K. H. Nuechterlein et al.   SCHIZOPHRENIA BULLETIN

Abnormal expression of glutamate transporter and transporter interacting molecules in prefrontal cortex in elderly patients with schizophrenia

(2008) Deborah Bauer et al.   SCHIZOPHRENIA RESEARCH

Galantamine for the Treatment of Cognitive Impairments in People With Schizophrenia

(2007) Robert W. Buchanan et al.   AMERICAN JOURNAL OF PSYCHIATRY

Lesions of the basal forebrain impair reversal learning but not shifting of attentional set in rats

(2007) David Scott Tait et al.   BEHAVIOURAL BRAIN RESEARCH

Differential effects of inactivation of the orbitofrontal cortex on strategy set-shifting and reversal learning

(2007) Sarvin Ghods-Sharifi et al.   NEUROBIOLOGY OF LEARNING AND MEMORY