Tracking Effects of SIL1 Increase: Taking a Closer Look Beyond the Consequences of Elevated Expression Level

Proteomic Analysis of Serum Proteins in Triple Transgenic Alzheimer's Disease Mice: Implications for Identifying Biomarkers for Use to Screen Potential Candidate Therapeutic Drugs for Early Alzheimer's Disease

(2018) Xiaojing Sui et al.   JOURNAL OF ALZHEIMERS DISEASE

Upregulation of Cytoplasmic Gelsolin, an Amyloid-β-Binding Protein, Under Oxidative Stress Conditions: Involvement of Protein Kinase C

(2017) Lina Ji et al.   JOURNAL OF ALZHEIMERS DISEASE

Aβ-Induced Synaptic Alterations Require the E3 Ubiquitin Ligase Nedd4-1

(2016) Elizabeth M. Rodrigues et al.   JOURNAL OF NEUROSCIENCE

The Role of Autophagy, Mitophagy and Lysosomal Functions in Modulating Bioenergetics and Survival in the Context of Redox and Proteotoxic Damage: Implications for Neurodegenerative Diseases

(2016) Matthew Redmann et al.   Aging and Disease

Homologous Transcription Factors DUX4 and DUX4c Associate with Cytoplasmic Proteins during Muscle Differentiation

(2016) Eugénie Ansseau et al.   PLoS One

FUS/TLS acts as an aggregation-dependent modifier of polyglutamine disease model mice

(2016) Yoshihiro Kino et al.   Scientific Reports

The unfolded protein response in neurodegenerative diseases: a neuropathological perspective

(2015) Wiep Scheper et al.   ACTA NEUROPATHOLOGICA

Function of Nogo-A/Nogo-A Receptor in Alzheimer's Disease

(2015) Ying-Qi Xu et al.   CNS Neuroscience & Therapeutics

Tetraspanin-3 is an organizer of the multi-subunit Nogo-A signaling complex

(2015) N. K. Thiede-Stan et al.   JOURNAL OF CELL SCIENCE

The regulation of p53 up-regulated modulator of apoptosis by JNK/c-Jun pathway in β-amyloid-induced neuron death

(2015) Rumana Akhter et al.   JOURNAL OF NEUROCHEMISTRY

SIL1 Rescued Bip Elevation-Related Tau Hyperphosphorylation in ER Stress

(2015) Zan-Chao Liu et al.   MOLECULAR NEUROBIOLOGY

Cellular Signature of SIL1 Depletion: Disease Pathogenesis due to Alterations in Protein Composition Beyond the ER Machinery

(2015) Andreas Roos et al.   MOLECULAR NEUROBIOLOGY

PeptideShaker enables reanalysis of MS-derived proteomics data sets

(2015) Marc Vaudel et al.   NATURE BIOTECHNOLOGY

Marinesco-Sjögren syndrome protein SIL1 regulates motor neuron subtype-selective ER stress in ALS

(2015) Audrey Filézac de L'Etang et al.   NATURE NEUROSCIENCE

Abnormal Activation of BMP Signaling Causes Myopathy in Fbn2 Null Mice

(2015) Gerhard Sengle et al.   PLoS Genetics

TIP47 is associated with the Hepatitis C virus and its interaction with Rab9 is required for release of viral particles

(2014) Daniela Ploen et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Skeletal Muscle Perilipin 3 and Coatomer Proteins Are Increased following Exercise and Are Associated with Fat Oxidation

(2014) Jeffrey D. Covington et al.   PLoS One

Myopathy in Marinesco–Sjögren syndrome links endoplasmic reticulum chaperone dysfunction to nuclear envelope pathology

(2013) Andreas Roos et al.   ACTA NEUROPATHOLOGICA

SIL1 mutations and clinical spectrum in patients with Marinesco-Sjögren syndrome

(2013) Michael Krieger et al.   BRAIN

The biological meaning of the UPR

(2013) Claudio Hetz   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Increased Tau Phosphorylation and Tau Truncation, and Decreased Synaptophysin Levels in Mutant BRI2/Tau Transgenic Mice

(2013) Holly J. Garringer et al.   PLoS One

The Effect of SOD1 Mutation on Cellular Bioenergetic Profile and Viability in Response to Oxidative Stress and Influence of Mutation-Type

(2013) Katie Richardson et al.   PLoS One

Protein carbamylation: In vivo modification or in vitro artefact?

(2013) Laxmikanth Kollipara et al.   PROTEOMICS

Stromal cell-derived factor 1α decreases β-amyloid deposition in Alzheimer's disease mouse model

(2012) Qi Wang et al.   BRAIN RESEARCH

BiP-mediated closing of the Sec61 channel limits Ca2+leakage from the ER

(2012) Nico Schäuble et al.   EMBO JOURNAL

C-terminal Mutations Destabilize SIL1/BAP and Can Cause Marinesco-Sjögren Syndrome

(2012) Jennifer Howes et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Oligomeric amyloid-β peptide affects the expression of genes involved in steroid and lipid metabolism in primary neurons

(2012) Bilal Malik et al.   NEUROCHEMISTRY INTERNATIONAL

JNK2 is activated during ER stress and promotes cell survival

(2012) M Raciti et al.   Cell Death & Disease

Hexosamine Biosynthetic Pathway Mutations Cause Neuromuscular Transmission Defect

(2011) Jan Senderek et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Structural analysis of the Sil1–Bip complex reveals the mechanism for Sil1 to function as a nucleotide-exchange factor

(2011) Ming Yan et al.   BIOCHEMICAL JOURNAL

Autophagy and BiP level decrease are early key events in retrograde degeneration of motoneurons

(2011) C Penas et al.   CELL DEATH AND DIFFERENTIATION

Ubiquitously Expressed Hematological and Neurological Expressed 1 Downregulates Akt-Mediated GSK3β Signaling, and Its Knockdown Results in Deregulated G2/M Transition in Prostate Cells

(2011) Lokman Varisli et al.   DNA AND CELL BIOLOGY

Ca2+-calmodulin inhibits tail-anchored protein insertion into the mammalian endoplasmic reticulum membrane

(2011) Sarah Haßdenteufel et al.   FEBS LETTERS

Systematic and quantitative comparison of digest efficiency and specificity reveals the impact of trypsin quality on MS-based proteomics

(2011) Julia Maria Burkhart et al.   Journal of Proteomics

Modeling cholesterol metabolism by gene expression profiling in the hippocampus

(2011) Christopher M. Valdez et al.   Molecular BioSystems

A Human TREK-1/HEK Cell Line: A Highly Efficient Screening Tool for Drug Development in Neurological Diseases

(2011) Hamid Moha ou Maati et al.   PLoS One

Differential Effects of Myopathy-Associated Caveolin-3 Mutants on Growth Factor Signaling

(2010) Eva Brauers et al.   AMERICAN JOURNAL OF PATHOLOGY

Effect of TBCD and its regulatory interactor Arl2 on tubulin and microtubule integrity

(2010) Guoling Tian et al.   Cytoskeleton

Ion channel activity of brain abundant protein BASP1 in planar lipid bilayers

(2010) Olga S. Ostroumova et al.   FEBS Journal

BiP Modulates the Affinity of Its Co-chaperone ERj1 for Ribosomes

(2010) Julia Benedix et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Novel Membrane Protein TMEM59 Modulates Complex Glycosylation, Cell Surface Expression, and Secretion of the Amyloid Precursor Protein

(2010) Sylvia Ullrich et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Annexin A1: A Central Player in the Anti-Inflammatory and Neuroprotective Role of Microglia

(2010) S. McArthur et al.   JOURNAL OF IMMUNOLOGY

The Planar Polarity Protein Scribble1 Is Essential for Neuronal Plasticity and Brain Function

(2010) M. M. Moreau et al.   JOURNAL OF NEUROSCIENCE

ERAL1 is associated with mitochondrial ribosome and elimination of ERAL1 leads to mitochondrial dysfunction and growth retardation

(2010) Takeshi Uchiumi et al.   NUCLEIC ACIDS RESEARCH

Essential role of the unfolded protein response regulator GRP78/BiP in protection from neuronal apoptosis

(2009) M Wang et al.   CELL DEATH AND DIFFERENTIATION

Functions and pathologies of BiP and its interaction partners

(2009) J. Dudek et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Oxidative Stress and Neurodegenerative Diseases: A Review of Upstream and Downstream Antioxidant Therapeutic Options

(2009) Bayani Uttara et al.   Current Neuropharmacology

Chaperone-mediated autophagy in health and disease

(2009) Maria Kon et al.   FEBS LETTERS

Alteration of the unfolded protein response modifies neurodegeneration in a mouse model of Marinesco–Sjögren syndrome

(2009) Lihong Zhao et al.   HUMAN MOLECULAR GENETICS

Universal sample preparation method for proteome analysis

(2009) Jacek R Wiśniewski et al.   NATURE METHODS

Modulation of Chaperone Gene Expression in Mutagenized Saccharomyces cerevisiae Strains Developed for Recombinant Human Albumin Production Results in Increased Production of Multiple Heterologous Proteins

(2008) T. Payne et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

The unfolded protein response regulator GRP78/BiP is required for endoplasmic reticulum integrity and stress-induced autophagy in mammalian cells

(2008) J Li et al.   CELL DEATH AND DIFFERENTIATION

Mammalian BiP controls posttranslational ER translocation of the hepatitis B virus large envelope protein

(2008) Karin Awe et al.   FEBS LETTERS

Vacuolar Degeneration of Skeletal Muscle in Transgenic Mice Overexpressing ORP150

(2008) Tomohiro KOBAYASHI et al.   JOURNAL OF VETERINARY MEDICAL SCIENCE

Substrate-Assisted Catalysis by PARP10 Limits Its Activity to Mono-ADP-Ribosylation

(2008) Henning Kleine et al.   MOLECULAR CELL