Modeling cholesterol metabolism by gene expression profiling in the hippocampus

Membrane Lipids, Selectively Diminished in Alzheimer Brains, Suggest Synapse Loss as a Primary Event in Early-Onset Form (Type I) and Demyelination in Late-Onset Form (Type II)

(2010) Lars Svennerholm et al.   JOURNAL OF NEUROCHEMISTRY

MicroRNA-33 and the SREBP Host Genes Cooperate to Control Cholesterol Homeostasis

(2010) S. H. Najafi-Shoushtari et al.   SCIENCE

MiR-33 Contributes to the Regulation of Cholesterol Homeostasis

(2010) K. J. Rayner et al.   SCIENCE

Quantifying the Effects of Elastic Collisions and Non-Covalent Binding on Glutamate Receptor Trafficking in the Post-Synaptic Density

(2010) Fidel Santamaria et al.   PLoS Computational Biology

Cholesterol-modifying strategies for Alzheimer’s disease

(2009) Alina Solomon et al.   Expert Review of Neurotherapeutics

Kinetic hybrid models composed of mechanistic and simplified enzymatic rate laws - a promising method for speeding up the kinetic modelling of complex metabolic networks

(2009) Sascha Bulik et al.   FEBS Journal

Quantification of statin effects on hepatic cholesterol synthesis by transient 13C-flux analysis

(2009) Klaus Maier et al.   METABOLIC ENGINEERING

Getting a handle on Huntington's disease: the case for cholesterol

(2009) Masahisa Katsuno et al.   NATURE MEDICINE

Regulation of the brain isoprenoids farnesyl- and geranylgeranylpyrophosphate is altered in male Alzheimer patients

(2009) Gunter P. Eckert et al.   NEUROBIOLOGY OF DISEASE

KINSOLVER: A simulator for computing large ensembles of biochemical and gene regulatory networks

(2008) Boanerges Aleman-Meza et al.   COMPUTERS & MATHEMATICS WITH APPLICATIONS

Reduced Risk of Incident AD with Elective Statin Use in a Clinical Trial Cohort

(2008) D. Sparks et al.   Current Alzheimer Research

Smith–Lemli–Opitz syndrome: pathogenesis, diagnosis and management

(2008) Forbes D Porter   EUROPEAN JOURNAL OF HUMAN GENETICS

Statins decrease dendritic arborization in rat sympathetic neurons by blocking RhoA activation

(2008) Woo-Yang Kim et al.   JOURNAL OF NEUROCHEMISTRY

Statins are associated with a reduced risk of Alzheimer disease regardless of lipophilicity. The Rotterdam Study

(2008) M D M Haag et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Mathematical analysis of models for reaction kinetics in intracellular environments

(2008) Željko Bajzer et al.   MATHEMATICAL BIOSCIENCES

Metabolic model integration of the bibliome, genome, metabolome and reactome of Aspergillus niger

(2008) Mikael Rørdam Andersen et al.   Molecular Systems Biology

Non-Markovian Model for Transport and Reactions of Particles in Spiny Dendrites

(2008) Sergei Fedotov et al.   PHYSICAL REVIEW LETTERS

Partial blockage of sterol biosynthesis with a squalene synthase inhibitor in early postnatal Niemann-Pick type C npcnih null mice brains reduces neuronal cholesterol accumulation, abrogates astrogliosis, but may inhibit myelin maturation

(2007) Patrick C. Reid et al.   JOURNAL OF NEUROSCIENCE METHODS