Increased Tau Phosphorylation and Tau Truncation, and Decreased Synaptophysin Levels in Mutant BRI2/Tau Transgenic Mice

Frontotemporal Dementia: Implications for Understanding Alzheimer Disease

(2013) M. Goedert et al.   Cold Spring Harbor Perspectives in Medicine

The Psen1-L166P-knock-in mutation leads to amyloid deposition in human wild-type amyloid precursor protein YAC transgenic mice

(2012) Ruben Vidal et al.   FASEB JOURNAL

APP heterozygosity averts memory deficit in knockin mice expressing the Danish dementia BRI2 mutant

(2011) Robert Tamayev et al.   EMBO JOURNAL

Intraneuronal APP, Not Free A  Peptides in 3xTg-AD Mice: Implications for Tau versus A -Mediated Alzheimer Neurodegeneration

(2011) M. J. Winton et al.   JOURNAL OF NEUROSCIENCE

Tau oligomers impair memory and induce synaptic and mitochondrial dysfunction in wild-type mice

(2011) Cristian A Lasagna-Reeves et al.   Molecular Neurodegeneration

Presence of Reactive Microglia and Neuroinflammatory Mediators in a Case of Frontotemporal Dementia with P301S Mutation

(2011) Arianna Bellucci et al.   Neurodegenerative Diseases

CATARACT, DEAFNESS, CEREBELLAR ATAXIA, PSYCHOSIS AND DEMENTIA-A NEW SYNDROME

(2010) E. Strömgren et al.   ACTA NEUROLOGICA SCANDINAVICA

Aβ Accelerates the Spatiotemporal Progression of Tau Pathology and Augments Tau Amyloidosis in an Alzheimer Mouse Model

(2010) David E. Hurtado et al.   AMERICAN JOURNAL OF PATHOLOGY

Memory Deficits Due to Familial British Dementia BRI2 Mutation Are Caused by Loss of BRI2 Function Rather than Amyloidosis

(2010) R. Tamayev et al.   JOURNAL OF NEUROSCIENCE

Caspase activation precedes and leads to tangles

(2010) Alix de Calignon et al.   NATURE

Danish dementia mice suggest that loss of function and not the amyloid cascade causes synaptic plasticity and memory deficits

(2010) R. Tamayev et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Modeling familial Danish dementia in mice supports the concept of the amyloid hypothesis of Alzheimer's disease

(2010) Janaky Coomaraswamy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Truncated tau at D421 is associated with neurodegeneration and tangle formation in the brain of Alzheimer transgenic models

(2009) Qipeng Zhang et al.   ACTA NEUROPATHOLOGICA

Misfolded tau protein and disease modifying pathways in transgenic rodent models of human tauopathies

(2009) Norbert Zilka et al.   ACTA NEUROPATHOLOGICA

Modeling familial British and Danish dementia

(2009) Holly J. Garringer et al.   Brain Structure & Function

Abnormal iron metabolism and oxidative stress in mice expressing a mutant form of the ferritin light polypeptide gene

(2009) Ana G. Barbeito et al.   JOURNAL OF NEUROCHEMISTRY

Generation and Initial Characterization of FDD Knock In Mice

(2009) Luca Giliberto et al.   PLoS One

Oligomeric amyloid   associates with postsynaptic densities and correlates with excitatory synapse loss near senile plaques

(2009) R. M. Koffie et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cerebral Amyloid Angiopathy and Parenchymal Amyloid Deposition in Transgenic Mice Expressing the Danish Mutant Form of Human BRI2

(2008) Ruben Vidal et al.   BRAIN PATHOLOGY

Microglial activation in brain lesions with tau deposits: Comparison of human tauopathies and tau transgenic mice TgTauP301L

(2008) Atsushi Sasaki et al.   BRAIN RESEARCH

Widespread Changes in Dendritic Spines in a Model of Alzheimer's Disease

(2008) S. Knafo et al.   CEREBRAL CORTEX

Substrate Requirements for SPPL2b-dependent Regulated Intramembrane Proteolysis

(2008) Lucas Martin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Expression of a Mutant Form of the Ferritin Light Chain Gene Induces Neurodegeneration and Iron Overload in Transgenic Mice

(2008) R. Vidal et al.   JOURNAL OF NEUROSCIENCE

In Vivo Imaging Reveals Dissociation between Caspase Activation and Acute Neuronal Death in Tangle-Bearing Neurons

(2008) T. L. Spires-Jones et al.   JOURNAL OF NEUROSCIENCE

Analysis of Tau Phosphorylation and Truncation in a Mouse Model of Human Tauopathy

(2007) Patrice Delobel et al.   AMERICAN JOURNAL OF PATHOLOGY

Tauopathy in human and experimental variant Creutzfeldt-Jakob disease

(2007) G. Giaccone et al.   NEUROBIOLOGY OF AGING