Linkage of A-to-I RNA Editing in Metazoans and the Impact on Genome Evolution

Systematic characterization of A-to-I RNA editing hotspots in microRNAs across human cancers

(2017) Yumeng Wang et al.   GENOME RESEARCH

A-to-I RNA Editing in the Earliest-Diverging Eumetazoan Phyla

(2017) Hagit T. Porath et al.   MOLECULAR BIOLOGY AND EVOLUTION

Accurately annotate compound effects of genetic variants using a context-sensitive framework

(2017) Si-Jin Cheng et al.   NUCLEIC ACIDS RESEARCH

Dynamic hyper-editing underlies temperature adaptation in Drosophila

(2017) Ilana Buchumenski et al.   PLoS Genetics

Evolutionary analysis reveals regulatory and functional landscape of coding and non-coding RNA editing

(2017) Rui Zhang et al.   PLoS Genetics

Adaptation of A-to-I RNA editing in Drosophila

(2017) Yuange Duan et al.   PLoS Genetics

A-to-I RNA editing promotes developmental stage–specific gene and lncRNA expression

(2016) Boaz Goldstein et al.   GENOME RESEARCH

Identification of human RNA editing sites: A historical perspective

(2016) Gokul Ramaswami et al.   METHODS

REDIportal: a comprehensive database of A-to-I RNA editing events in humans

(2016) Ernesto Picardi et al.   NUCLEIC ACIDS RESEARCH

The Landscape of A-to-I RNA Editome Is Shaped by Both Positive and Purifying Selection

(2016) Yao Yu et al.   PLoS Genetics

DNA and RNA editing of retrotransposons accelerate mammalian genome evolution

(2015) Binyamin A. Knisbacher et al.   Annals of the New York Academy of Sciences

The Genomic Landscape and Clinical Relevance of A-to-I RNA Editing in Human Cancers

(2015) Leng Han et al.   CANCER CELL

Genetic Architectures of Quantitative Variation in RNA Editing Pathways

(2015) T. Gu et al.   GENETICS

The emerging role of RNA editing in plasticity

(2015) J. J. C. Rosenthal   JOURNAL OF EXPERIMENTAL BIOLOGY

Genome sequence–independent identification of RNA editing sites

(2015) Qing Zhang et al.   NATURE METHODS

A-to-I editing of coding and non-coding RNAs by ADARs

(2015) Kazuko Nishikura   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Genome-wide identification and characterization of tissue-specific RNA editing events inD. melanogasterand their potential role in regulating alternative splicing

(2015) Alborz Mazloomian et al.   RNA Biology

Genetic mapping uncovers cis-regulatory landscape of RNA editing

(2015) Gokul Ramaswami et al.   Nature Communications

Profiling RNA editing in human tissues: towards the inosinome Atlas

(2015) Ernesto Picardi et al.   Scientific Reports

Elevated RNA Editing Activity Is a Major Contributor to Transcriptomic Diversity in Tumors

(2015) Nurit Paz-Yaacov et al.   Cell Reports

Genetic Determinants of RNA Editing Levels of ADAR Targets in Drosophila melanogaster

(2015) Yerbol Z. Kurmangaliyev et al.   G3-Genes Genomes Genetics

Global Diversity Lines–A Five-Continent Reference Panel of Sequenced Drosophila melanogaster Strains

(2015) Jennifer K. Grenier et al.   G3-Genes Genomes Genetics

Global Analysis of Mouse Polyomavirus Infection Reveals Dynamic Regulation of Viral and Host Gene Expression and Promiscuous Viral RNA Editing

(2015) Seth B. Garren et al.   PLoS Pathogens

The majority of transcripts in the squid nervous system are extensively recoded by A-to-I RNA editing

(2015) Shahar Alon et al.   eLife

Animal Phylogeny and Its Evolutionary Implications

(2014) Casey W. Dunn et al.   Annual Review of Ecology Evolution and Systematics

Does RNA editing compensate for Alu invasion of the primate genome?

(2014) Erez Y. Levanon et al.   BIOESSAYS

Profiling the RNA editomes of wild-typeC. elegansand ADAR mutants

(2014) Han-Qing Zhao et al.   GENOME RESEARCH

A biochemical landscape of A-to-I RNA editing in the human brain transcriptome

(2014) M. Sakurai et al.   GENOME RESEARCH

In Search of Beneficial Coding RNA Editing

(2014) Guixia Xu et al.   MOLECULAR BIOLOGY AND EVOLUTION

Human coding RNA editing is generally nonadaptive

(2014) G. Xu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Caste-specific RNA editomes in the leaf-cutting ant Acromyrmex echinatior

(2014) Qiye Li et al.   Nature Communications

A genome-wide map of hyper-edited RNA reveals numerous new sites

(2014) Hagit T. Porath et al.   Nature Communications

RNA Editome in Rhesus Macaque Shaped by Purifying Selection

(2014) Jia-Yu Chen et al.   PLoS Genetics

Mammalian conserved ADAR targets comprise only a small fragment of the human editosome

(2014) Yishay Pinto et al.   GENOME BIOLOGY

How epigenetic mutations can affect genetic evolution: Model and mechanism

(2013) Filippos D. Klironomos et al.   BIOESSAYS

A-to-I RNA editing occurs at over a hundred million genomic sites, located in a majority of human genes

(2013) L. Bazak et al.   GENOME RESEARCH

Identifying RNA editing sites using RNA sequencing data alone

(2013) Gokul Ramaswami et al.   NATURE METHODS

Deciphering the functions and regulation of brain-enriched A-to-I RNA editing

(2013) Jin Billy Li et al.   NATURE NEUROSCIENCE

Genome-wide analysis of A-to-I RNA editing by single-molecule sequencing in Drosophila

(2013) Georges St Laurent et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

RADAR: a rigorously annotated database of A-to-I RNA editing

(2013) Gokul Ramaswami et al.   NUCLEIC ACIDS RESEARCH

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

A program for annotating and predicting the effects of single nucleotide polymorphisms, SnpEff

(2012) Pablo Cingolani et al.   FLY

Systematic identification of edited microRNAs in the human brain

(2012) S. Alon et al.   GENOME RESEARCH

Nascent-Seq Indicates Widespread Cotranscriptional RNA Editing in Drosophila

(2012) Joseph Rodriguez et al.   MOLECULAR CELL

Comprehensive analysis of RNA-Seq data reveals extensive RNA editing in a human transcriptome

(2012) Zhiyu Peng et al.   NATURE BIOTECHNOLOGY

Insights from honeybee (Apis mellifera) and fly (Drosophila melanogaster) nicotinic acetylcholine receptors: From genes to behavioral functions

(2012) Julien Dupuis et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

RNA Editing Underlies Temperature Adaptation in K+ Channels from Polar Octopuses

(2012) S. Garrett et al.   SCIENCE

Auto-regulatory RNA editing fine-tunes mRNA re-coding and complex behaviour in Drosophila

(2012) Yiannis A. Savva et al.   Nature Communications

The Genomic Landscape and Evolutionary Resolution of Antagonistic Pleiotropy in Yeast

(2012) Wenfeng Qian et al.   Cell Reports

The ADAR protein family

(2012) Yiannis A Savva et al.   GENOME BIOLOGY

High levels of RNA-editing site conservation amongst 15 laboratory mouse strains

(2012) Petr Daneck et al.   GENOME BIOLOGY

ViennaRNA Package 2.0

(2011) Ronny Lorenz et al.   Algorithms for Molecular Biology

A statistical framework for SNP calling, mutation discovery, association mapping and population genetical parameter estimation from sequencing data

(2011) H. Li   BIOINFORMATICS

The pleiotropic structure of the genotype–phenotype map: the evolvability of complex organisms

(2011) Günter P. Wagner et al.   NATURE REVIEWS GENETICS

Identification of Widespread Ultra-Edited Human RNAs

(2011) Shai Carmi et al.   PLoS Genetics

Functions and Regulation of RNA Editing by ADAR Deaminases

(2010) Kazuko Nishikura   Annual Review of Biochemistry

Large-scale analysis of structural, sequence and thermodynamic characteristics of A-to-I RNA editing sites in human Alu repeats

(2010) Yoav Kleinberger et al.   BMC GENOMICS

Engineered Alterations in RNA Editing Modulate Complex Behavior inDrosophila

(2010) James E. C. Jepson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The developmental transcriptome of Drosophila melanogaster

(2010) Brenton R. Graveley et al.   NATURE

RNA editing: a driving force for adaptive evolution?

(2009) Willemijn M. Gommans et al.   BIOESSAYS

Adenosine deamination in human transcripts generates novel microRNA binding sites

(2009) Glen M. Borchert et al.   HUMAN MOLECULAR GENETICS

Widespread cleavage of A-to-I hyperediting substrates

(2009) S. Osenberg et al.   RNA

Genome-Wide Identification of Human RNA Editing Sites by Parallel DNA Capturing and Sequencing

(2009) J. B. Li et al.   SCIENCE

Linkage disequilibrium — understanding the evolutionary past and mapping the medical future

(2008) Montgomery Slatkin   NATURE REVIEWS GENETICS

Identification of SLEEPLESS, a Sleep-Promoting Factor

(2008) K. Koh et al.   SCIENCE

RNA editing in regulating gene expression in the brain

(2007) James E.C. Jepson et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms