Paucimannose-RichN-glycosylation of Spatiotemporally Regulated Human Neutrophil Elastase Modulates Its Immune Functions

Alpha-1 Antitrypsin Mitigates the Inhibition of Airway Epithelial Cell Repair by Neutrophil Elastase

(2016) Luke W. Garratt et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Neutrophils in cystic fibrosis

(2016) Julie Laval et al.   BIOLOGICAL CHEMISTRY

Myeloperoxidase Stimulates Neutrophil Degranulation

(2016) D. V. Grigorieva et al.   BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE

Neutrophil elastase enhances antigen presentation by upregulating human leukocyte antigen class I expression on tumor cells

(2016) Akhil Chawla et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Preeclampsia transforms membrane N-glycome in human placenta

(2016) Dragana Robajac et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Neutral serine proteases of neutrophils

(2016) Ralph Kettritz   IMMUNOLOGICAL REVIEWS

Neutrophils in the tumor microenvironment: trying to heal the wound that cannot heal

(2016) Kelly L. Singel et al.   IMMUNOLOGICAL REVIEWS

Granulopoiesis and granules of human neutrophils

(2016) Jack B. Cowland et al.   IMMUNOLOGICAL REVIEWS

Neutrophil azurophilic granule exocytosis is primed by TNF-α and partially regulated by NADPH oxidase

(2016) Renee M Potera et al.   Innate Immunity

Asn347Glycosylation of Corticosteroid-binding Globulin Fine-tunes the Host Immune Response by Modulating Proteolysis byPseudomonas aeruginosaand Neutrophil Elastase

(2016) Zeynep Sumer-Bayraktar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Neutrophil extracellular traps — the dark side of neutrophils

(2016) Ole E. Sørensen et al.   JOURNAL OF CLINICAL INVESTIGATION

A Surface Biotinylation Strategy for Reproducible Plasma Membrane Protein Purification and Tracking of Genetic and Drug-Induced Alterations

(2016) Katrin Hörmann et al.   JOURNAL OF PROTEOME RESEARCH

Toward Automated N-Glycopeptide Identification in Glycoproteomics

(2016) Ling Y. Lee et al.   JOURNAL OF PROTEOME RESEARCH

Emerging roles of protein mannosylation in inflammation and infection

(2016) Ian Loke et al.   MOLECULAR ASPECTS OF MEDICINE

Glycosylation site occupancy in health, congenital disorder of glycosylation and fatty liver disease

(2016) Andreas J. Hülsmeier et al.   Scientific Reports

α-1-Antitrypsin variants and the proteinase/antiproteinase imbalance in chronic obstructive pulmonary disease

(2015) Nicola J. Sinden et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

In-depthN-glycome profiling of paired colorectal cancer and non-tumorigenic tissues reveals cancer-, stage- and EGFR-specific protein N-glycosylation

(2015) Manveen K Sethi et al.   GLYCOBIOLOGY

Symbol Nomenclature for Graphical Representations of Glycans

(2015) Ajit Varki et al.   GLYCOBIOLOGY

Human Neutrophils Secrete Bioactive Paucimannosidic Proteins from Azurophilic Granules into Pathogen-Infected Sputum

(2015) Morten Thaysen-Andersen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pathogenesis of ELANE-mutant severe neutropenia revealed by induced pluripotent stem cells

(2015) Ramesh C. Nayak et al.   JOURNAL OF CLINICAL INVESTIGATION

Terminal Galactosylation and Sialylation Switching on Membrane Glycoproteins upon TNF-Alpha-Induced Insulin Resistance in Adipocytes

(2015) Benjamin L. Parker et al.   MOLECULAR & CELLULAR PROTEOMICS

Genetically and Phenotypically Distinct Pseudomonas aeruginosa Cystic Fibrosis Isolates Share a Core Proteomic Signature

(2015) Anahit Penesyan et al.   PLoS One

The glycobiology of the CD system: a dictionary for translating marker designations into glycan/lectin structure and function

(2015) Hans-Joachim Gabius et al.   TRENDS IN BIOCHEMICAL SCIENCES

Protein post-translational modification in host defense: the antimicrobial mechanism of action of human eosinophil cationic protein native forms

(2014) Vivian A. Salazar et al.   FEBS Journal

Cystic fibrosis and bacterial colonization define the sputum N-glycosylation phenotype

(2014) Vignesh Venkatakrishnan et al.   GLYCOBIOLOGY

Understanding the specificity of serpin–protease complexes through interface analysis

(2014) Qudsia Rashid et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

Neutrophil Elastase Mediates Innate Host Protection against Pseudomonas aeruginosa

(2014) T. O. Hirche et al.   JOURNAL OF IMMUNOLOGY

The Role and Importance of Glycosylation of Acute Phase Proteins with Focus on Alpha-1 Antitrypsin in Acute and Chronic Inflammatory Conditions

(2014) Cormac McCarthy et al.   JOURNAL OF PROTEOME RESEARCH

Neutrophils at work

(2014) William M Nauseef et al.   NATURE IMMUNOLOGY

Top-down tandem mass spectrometry on RNase A and B using a Qh/FT-ICR hybrid mass spectrometer

(2014) Sandrine Bourgoin-Voillard et al.   PROTEOMICS

A Myeloperoxidase-Containing Complex Regulates Neutrophil Elastase Release and Actin Dynamics during NETosis

(2014) Kathleen D. Metzler et al.   Cell Reports

Differential Site Accessibility Mechanistically Explains Subcellular-Specific N-Glycosylation Determinants

(2014) Ling Yen Lee et al.   Frontiers in Immunology

The Neutrophil in Chronic Obstructive Pulmonary Disease. Too Little, Too Late or Too Much, Too Soon?

(2013) Kim Hoenderdos et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

N-linked protein glycosylation in the ER

(2013) Markus Aebi   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Neutropenia-associated ELANE mutations disrupting translation initiation produce novel neutrophil elastase isoforms

(2013) T. Tidwell et al.   BLOOD

Basal Autophagy Is Required for the Efficient Catabolism of Sialyloligosaccharides

(2013) Junichi Seino et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Proteome profiling of human neutrophil granule subsets, secretory vesicles, and cell membrane: correlation with transcriptome profiling of neutrophil precursors

(2013) Sara Rørvig et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Quantitative mapping of glycoprotein micro-heterogeneity and macro-heterogeneity: an evaluation of mass spectrometry signal strengths using synthetic peptides and glycopeptides

(2013) Kathrin Stavenhagen et al.   JOURNAL OF MASS SPECTROMETRY

Increased Outer Arm and Core Fucose Residues on the N-Glycans of Mutated Alpha-1 Antitrypsin Protein from Alpha-1 Antitrypsin Deficient Individuals

(2013) Cormac McCarthy et al.   JOURNAL OF PROTEOME RESEARCH

Structural Feature Ions for Distinguishing N- and O-Linked Glycan Isomers by LC-ESI-IT MS/MS

(2013) Arun V. Everest-Dass et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Total Protein Analysis as a Reliable Loading Control for Quantitative Fluorescent Western Blotting

(2013) Samantha L. Eaton et al.   PLoS One

Neutrophil Elastase Degrades Cystic Fibrosis Transmembrane Conductance Regulator via Calpains and Disables Channel FunctionIn VitroandIn Vivo

(2012) Mathieu Le Gars et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Effective Use of Mass Spectrometry for Glycan and Glycopeptide Structural Analysis

(2012) Nancy Leymarie et al.   ANALYTICAL CHEMISTRY

Site-specific glycoproteomics confirms that protein structure dictates formation of N-glycan type, core fucosylation and branching

(2012) Morten Thaysen-Andersen et al.   GLYCOBIOLOGY

Mannitou Monoclonal Antibody Uniquely Recognizes Paucimannose, a Marker for Human Cancer, Stemness, and Inflammation

(2012) Birgit Zipser et al.   JOURNAL OF CARBOHYDRATE CHEMISTRY

Structural analysis of N- and O-glycans released from glycoproteins

(2012) Pia H Jensen et al.   Nature Protocols

Conformations, dynamics and interactions of di-, tri- and pentamannoside with mannose binding lectin: a molecular dynamics study

(2011) Parichita Mazumder et al.   CARBOHYDRATE RESEARCH

Alpha-1-antitrypsin is produced by human neutrophil granulocytes and their precursors and liberated during granule exocytosis

(2011) Stine N. Clemmensen et al.   EUROPEAN JOURNAL OF HAEMATOLOGY

Unexpected Active-Site Flexibility in the Structure of Human Neutrophil Elastase in Complex with a New Dihydropyrimidone Inhibitor

(2011) Guido Hansen et al.   JOURNAL OF MOLECULAR BIOLOGY

Proteinase 3 carries small unusual carbohydrates and associates with αlpha-defensins

(2011) Morten Zoega et al.   Journal of Proteomics

Utilizing Ion-Pairing Hydrophilic Interaction Chromatography Solid Phase Extraction for Efficient Glycopeptide Enrichment in Glycoproteomics

(2010) Simon Mysling et al.   ANALYTICAL CHEMISTRY

Effects of glycosylation on the stability and flexibility of a metastable protein: The human serpin α1-antitrypsin

(2010) Anindya Sarkar et al.   INTERNATIONAL JOURNAL OF MASS SPECTROMETRY

Neutrophil elastase and myeloperoxidase regulate the formation of neutrophil extracellular traps

(2010) Venizelos Papayannopoulos et al.   JOURNAL OF CELL BIOLOGY

Serine protease activity contributes to control of Mycobacterium tuberculosis in hypoxic lung granulomas in mice

(2010) Stephen T. Reece et al.   JOURNAL OF CLINICAL INVESTIGATION

Neutrophil Elastase, Proteinase 3, and Cathepsin G as Therapeutic Targets in Human Diseases

(2010) B. Korkmaz et al.   PHARMACOLOGICAL REVIEWS

Mannose-binding lectin and innate immunity

(2009) W. K. Eddie Ip et al.   IMMUNOLOGICAL REVIEWS

Oligomerization of the Macrophage Mannose Receptor Enhances gp120-mediated Binding of HIV-1

(2009) Joey Lai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ficolin-1 is present in a highly mobilizable subset of human neutrophil granules and associates with the cell surface after stimulation with fMLP

(2009) Sara Rørvig et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Glycopeptide analysis by mass spectrometry

(2008) Dilusha S. Dalpathado et al.   ANALYST

Accumulation of free complex-type N-glycans in MKN7 and MKN45 stomach cancer cells

(2008) Aya Ishizuka et al.   BIOCHEMICAL JOURNAL

X-ray Snapshot of the Mechanism of Inactivation of Human Neutrophil Elastase by 1,2,5-Thiadiazolidin-3-one 1,1-Dioxide Derivatives†

(2008) Weijun Huang et al.   JOURNAL OF MEDICINAL CHEMISTRY

GlycoWorkbench: A Tool for the Computer-Assisted Annotation of Mass Spectra of Glycans†

(2008) Alessio Ceroni et al.   JOURNAL OF PROTEOME RESEARCH

Measuring elastase, proteinase 3 and cathepsin G activities at the surface of human neutrophils with fluorescence resonance energy transfer substrates

(2008) Brice Korkmaz et al.   Nature Protocols

Analysis of immunoglobulin glycosylation by LC-ESI-MS of glycopeptides and oligosaccharides

(2008) Johannes Stadlmann et al.   PROTEOMICS

Mannose-binding lectin is present in the infected airway: a possible pulmonary defence mechanism

(2008) K J Fidler et al.   THORAX

Neutrophil elastase, proteinase 3 and cathepsin G: Physicochemical properties, activity and physiopathological functions

(2007) Brice Korkmaz et al.   BIOCHIMIE