The Identification of a SIRT6 Activator from Brown Algae Fucus distichus

Pharmacological Sirt6 inhibition improves glucose tolerance in a type 2 diabetes mouse model

(2017) Giovanna Sociali et al.   FASEB JOURNAL

SIRT7 Is Activated by DNA and Deacetylates Histone H3 in the Chromatin Context

(2016) Zhen Tong et al.   ACS Chemical Biology

Low-Molecular-Weight Fucoidan Attenuates Mitochondrial Dysfunction and Improves Neurological Outcome After Traumatic Brain Injury in Aged Mice: Involvement of Sirt3

(2016) Tao Wang et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Antimicrobial Action of Compounds from Marine Seaweed

(2016) María Pérez et al.   Marine Drugs

N-Acylethanolamines Bind to SIRT6

(2015) Minna Rahnasto-Rilla et al.   CHEMBIOCHEM

Protective Effect of Diphlorethohydroxycarmalol against Ultraviolet B Radiation-Induced DNA Damage by Inducing the Nucleotide Excision Repair System in HaCaT Human Keratinocytes

(2015) Mei Piao et al.   Marine Drugs

The effects of fucodian on senescence are controlled by the p16INK4a-pRb and p14Arf-p53 pathways in hepatocellular carcinoma and hepatic cell lines

(2014) EUN-YOUNG MIN et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Fucoidan Inhibits the Proliferation of Human Urinary Bladder Cancer T24 Cells by Blocking Cell Cycle Progression and Inducing Apoptosis

(2014) Hye Park et al.   MOLECULES

Tumor suppressor p53 cooperates with SIRT6 to regulate gluconeogenesis by promoting FoxO1 nuclear exclusion

(2014) P. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

SIRT6, a protein with many faces

(2013) Asaf A. Gertler et al.   BIOGERONTOLOGY

Enrichment of polyphenol contents and antioxidant activities of Irish brown macroalgae using food-friendly techniques based on polarity and molecular size

(2013) Michelle S. Tierney et al.   FOOD CHEMISTRY

Activation of the Protein Deacetylase SIRT6 by Long-chain Fatty Acids and Widespread Deacylation by Mammalian Sirtuins

(2013) Jessica L. Feldman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Effect of Sulfated (1→3)-α-l-Fucan from the Brown Alga Saccharina cichorioides Miyabe on Resveratrol-Induced Apoptosis in Colon Carcinoma Cells

(2013) Olesia Vishchuk et al.   Marine Drugs

Structural Characteristics and Anticancer Activity of Fucoidan from the Brown Alga Sargassum mcclurei

(2013) Pham Thinh et al.   Marine Drugs

Sirt6 suppresses hepatocellular carcinoma cell growth via inhibiting the extracellular signal-regulated kinase signaling pathway

(2013) ZHI-GAO ZHANG et al.   Molecular Medicine Reports

SIRT6 regulates TNF-α secretion through hydrolysis of long-chain fatty acyl lysine

(2013) Hong Jiang et al.   NATURE

Influence of pressurised liquid extraction and solid-liquid extraction methods on the phenolic content and antioxidant activities of Irish macroalgae

(2012) Michelle S. Tierney et al.   INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY

The Deacetylase Sirt6 Activates the Acetyltransferase GCN5 and Suppresses Hepatic Gluconeogenesis

(2012) John E. Dominy et al.   MOLECULAR CELL

The sirtuin SIRT6 regulates lifespan in male mice

(2012) Yariv Kanfi et al.   NATURE

Can Phlorotannins Purified Extracts Constitute a Novel Pharmacological Alternative for Microbial Infections with Associated Inflammatory Conditions?

(2012) Graciliana Lopes et al.   PLoS One

SIRT6 overexpression induces massive apoptosis in cancer cells but not in normal cells

(2011) Michael Van Meter et al.   CELL CYCLE

An Unfractionated Fucoidan fromAscophyllum nodosum: Extraction, Characterization, and Apoptotic Effects in Vitro

(2011) Sarah A. Foley et al.   JOURNAL OF NATURAL PRODUCTS

Fucoidan from Undaria pinnatifida Induces Apoptosis in A549 Human Lung Carcinoma Cells

(2011) Hye-Jin Boo et al.   PHYTOTHERAPY RESEARCH

Mammalian Sirtuins: Biological Insights and Disease Relevance

(2010) Marcia C. Haigis et al.   Annual Review of Pathology-Mechanisms of Disease

The Histone Deacetylase Sirt6 Regulates Glucose Homeostasis via Hif1α

(2010) Lei Zhong et al.   CELL

Bio-Prospecting of a Few Brown Seaweeds for Their Cytotoxic and Antioxidant Activities

(2010) Rashmi C. Vinayak et al.   Evidence-based Complementary and Alternative Medicine

Total phenolic compounds, radical scavenging and metal chelation of extracts from Icelandic seaweeds

(2009) Tao Wang et al.   FOOD CHEMISTRY

Nϵ-Thioacetyl-Lysine-Containing Tri-, Tetra-, and Pentapeptides as SIRT1 and SIRT2 Inhibitors

(2009) Päivi H. Kiviranta et al.   JOURNAL OF MEDICINAL CHEMISTRY

Inhibition of histone acetyltransferase by glycosaminoglycans

(2008) Jo Ann Buczek-Thomas et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Fucoidan: Structure and Bioactivity

(2008) Bo Li et al.   MOLECULES