Targeting c-Met in Cancer by MicroRNAs: Potential Therapeutic Applications in Hepatocellular Carcinoma
Published 2015 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Targeting c-Met in Cancer by MicroRNAs: Potential Therapeutic Applications in Hepatocellular Carcinoma
Authors
Keywords
-
Journal
DRUG DEVELOPMENT RESEARCH
Volume 76, Issue 7, Pages 357-367
Publisher
Wiley
Online
2015-09-12
DOI
10.1002/ddr.21274
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- In vivo delivery of miRNAs for cancer therapy: Challenges and strategies
- (2015) Yunching Chen et al. ADVANCED DRUG DELIVERY REVIEWS
- The Interplay Between miR-148a and DNMT1 Might be Exploited for Pancreatic Cancer Therapy
- (2015) Qian Zhan et al. CANCER INVESTIGATION
- miR-454 is down-regulated in osteosarcomas and suppresses cell proliferation and invasion by directly targeting c-Met
- (2015) Guangfeng Niu et al. CELL PROLIFERATION
- Hepatocyte growth factor and Met in drug discovery
- (2015) K. Sakai et al. JOURNAL OF BIOCHEMISTRY
- miR-122 – A key factor and therapeutic target in liver disease
- (2015) Simonetta Bandiera et al. JOURNAL OF HEPATOLOGY
- MiR-144 Inhibits Uveal Melanoma Cell Proliferation and Invasion by Regulating c-Met Expression
- (2015) Lei Sun et al. PLoS One
- Cancer nanomedicine: from targeted delivery to combination therapy
- (2015) Xiaoyang Xu et al. TRENDS IN MOLECULAR MEDICINE
- Gα12 overexpressed in hepatocellular carcinoma reduces microRNA-122 expression via HNF4α inactivation, which causes c-Met induction
- (2015) Yoon Mee Yang et al. Oncotarget
- The hypoxia-related microRNA miR-199a-3p displays tumor suppressor functions in ovarian carcinoma
- (2015) Yasuto Kinose et al. Oncotarget
- MicroRNA-93 activates c-Met/PI3K/Akt pathway activity in hepatocellular carcinoma by directly inhibiting PTEN and CDKN1A
- (2015) Katsuya Ohta et al. Oncotarget
- Absolute quantification of cell-free microRNAs in cancer patients
- (2015) Manuela Ferracin et al. Oncotarget
- High circulating hepatocyte growth factor levels associate with epithelial to mesenchymal transition and poor outcome in small cell lung cancer patients
- (2015) Israel Cañadas et al. Oncotarget
- miR-199a-3p displays tumor suppressor functions in papillary thyroid carcinoma
- (2015) Emanuela Minna et al. Oncotarget
- miR-34: from bench to bedside
- (2015) Massimiliano Agostini et al. Oncotarget
- European cancer mortality predictions for the year 2014
- (2014) M. Malvezzi et al. ANNALS OF ONCOLOGY
- miR-181a-5p is downregulated in hepatocellular carcinoma and suppresses motility, invasion and branching-morphogenesis by directly targeting c-Met
- (2014) Peyda Korhan et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- MicroRNA-34A inhibits the growth, invasion and metastasis of gastric cancer by targeting PDGFR and MET expression
- (2014) Yang Peng et al. BIOSCIENCE REPORTS
- Cancer statistics, 2014
- (2014) Rebecca Siegel et al. CA-A CANCER JOURNAL FOR CLINICIANS
- MicroRNA-34a overcomes HGF-mediated gefitinib resistance in EGFR mutant lung cancer cells partly by targeting MET
- (2014) Jian-Ya Zhou et al. CANCER LETTERS
- Thirty Years of Research on Met Receptor to Move a Biomarker from Bench to Bedside
- (2014) A. Furlan et al. CANCER RESEARCH
- Projecting Cancer Incidence and Deaths to 2030: The Unexpected Burden of Thyroid, Liver, and Pancreas Cancers in the United States
- (2014) L. Rahib et al. CANCER RESEARCH
- Cabozantinib Suppresses Tumor Growth and Metastasis in Hepatocellular Carcinoma by a Dual Blockade of VEGFR2 and MET
- (2014) Q. Xiang et al. CLINICAL CANCER RESEARCH
- Cancer incidence and mortality worldwide: Sources, methods and major patterns in GLOBOCAN 2012
- (2014) Jacques Ferlay et al. INTERNATIONAL JOURNAL OF CANCER
- Systemic Delivery of a miR34a Mimic as a Potential Therapeutic for Liver Cancer
- (2014) C. L. Daige et al. MOLECULAR CANCER THERAPEUTICS
- Drug development: Try and try again
- (2014) Megan Scudellari NATURE
- MET inhibitors start on road to recovery
- (2014) Ken Garber NATURE REVIEWS DRUG DISCOVERY
- Therapeutic targeting of microRNAs: current status and future challenges
- (2014) Zhonghan Li et al. NATURE REVIEWS DRUG DISCOVERY
- The Met receptor tyrosine kinase: A key player in oncogenesis and drug resistance
- (2014) Christiane R. Maroun et al. PHARMACOLOGY & THERAPEUTICS
- MiR-133b Is Down-Regulated in Human Osteosarcoma and Inhibits Osteosarcoma Cells Proliferation, Migration and Invasion, and Promotes Apoptosis
- (2014) Huafu Zhao et al. PLoS One
- Reciprocal Activating Crosstalk between c-Met and Caveolin 1 Promotes Invasive Phenotype in Hepatocellular Carcinoma
- (2014) Peyda Korhan et al. PLoS One
- MiR-335 inhibits migration of breast cancer cells through targeting oncoprotein c-Met
- (2014) Yue Gao et al. TUMOR BIOLOGY
- miR-199a-3p inhibits hepatocyte growth factor/c-Met signaling in renal cancer carcinoma
- (2014) Jiwei Huang et al. TUMOR BIOLOGY
- The p53/miR-34 axis in development and disease
- (2014) M. Rokavec et al. Journal of Molecular Cell Biology
- miR-34 Cooperates with p53 in Suppression of Prostate Cancer by Joint Regulation of Stem Cell Compartment
- (2014) Chieh-Yang Cheng et al. Cell Reports
- MiR-34a targets GAS1 to promote cell proliferation and inhibit apoptosis in papillary thyroid carcinoma via PI3K/Akt/Bad pathway
- (2013) Yanfei Ma et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- miR-148a plays a pivotal role in the liver by promoting the hepatospecific phenotype and suppressing the invasiveness of transformed cells
- (2013) Luc Gailhouste et al. HEPATOLOGY
- MicroRNA-26a suppresses angiogenesis in human hepatocellular carcinoma by targeting hepatocyte growth factor-cMet pathway
- (2013) Xin Yang et al. HEPATOLOGY
- New Challenges and Inspired Answers for Anticancer Drug Discovery and Development
- (2013) T. Utsugi JAPANESE JOURNAL OF CLINICAL ONCOLOGY
- MicroRNA-148a suppresses the epithelial–mesenchymal transition and metastasis of hepatoma cells by targeting Met/Snail signaling
- (2013) J-P Zhang et al. ONCOGENE
- Underexpression of miR-34a in Hepatocellular Carcinoma and Its Contribution towards Enhancement of Proliferating Inhibitory Effects of Agents Targeting c-MET
- (2013) Yiwu Dang et al. PLoS One
- MicroRNA-449a Is Downregulated in Non-Small Cell Lung Cancer and Inhibits Migration and Invasion by Targeting c-Met
- (2013) Wenting Luo et al. PLoS One
- miR-26a and its Target CKS2 Modulate Cell Growth and Tumorigenesis of Papillary Thyroid Carcinoma
- (2013) Mingli Lv et al. PLoS One
- MicroRNA-26a Inhibits Angiogenesis by Down-Regulating VEGFA through the PIK3C2α/Akt/HIF-1α Pathway in Hepatocellular Carcinoma
- (2013) Zong-Tao Chai et al. PLoS One
- miR-122 Regulates Tumorigenesis in Hepatocellular Carcinoma by Targeting AKT3
- (2013) Rounak Nassirpour et al. PLoS One
- Monovalent antibody design and mechanism of action of onartuzumab, a MET antagonist with anti-tumor activity as a therapeutic agent
- (2013) M. Merchant et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Treating hepatocellular carcinoma progression following first-line sorafenib: therapeutic options and clinical observations
- (2013) A. Ruth He et al. Therapeutic Advances in Gastroenterology
- Detection of miR-34a Promoter Methylation in Combination with Elevated Expression of c-Met and -Catenin Predicts Distant Metastasis of Colon Cancer
- (2012) H. Siemens et al. CLINICAL CANCER RESEARCH
- Histone Deacetylases Activate Hepatocyte Growth Factor Signaling by Repressing MicroRNA-449 in Hepatocellular Carcinoma Cells
- (2012) Reena Buurman et al. GASTROENTEROLOGY
- MicroRNAs: New tools for diagnosis, prognosis, and therapy in hepatocellular carcinoma?
- (2012) Silvia Giordano et al. HEPATOLOGY
- Cooperative interaction of MUC1 with the HGF/c-Met pathway during hepatocarcinogenesis
- (2012) Giray Bozkaya et al. Molecular Cancer
- miRNA Profiling in Colorectal Cancer Highlights miR-1 Involvement in MET-Dependent Proliferation
- (2012) J. F. Reid et al. MOLECULAR CANCER RESEARCH
- Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors
- (2012) Timothy R. Wilson et al. NATURE
- Autocrine activation of the MET receptor tyrosine kinase in acute myeloid leukemia
- (2012) Alex Kentsis et al. NATURE MEDICINE
- MET: a promising anticancer therapeutic target
- (2012) Solange Peters et al. Nature Reviews Clinical Oncology
- Medical therapies for hepatocellular carcinoma: a critical view of the evidence
- (2012) Augusto Villanueva et al. Nature Reviews Gastroenterology & Hepatology
- Plasma Hepatocyte Growth Factor Elevation May Be Associated with Early Metastatic Disease in Primary Lung Cancer Patients
- (2011) Hiroshi Hosoda et al. Annals of Thoracic and Cardiovascular Surgery
- miR-340 inhibition of breast cancer cell migration and invasion through targeting of oncoprotein c-Met
- (2011) Zheng-sheng Wu et al. CANCER
- Identification of miRNomes in Human Liver and Hepatocellular Carcinoma Reveals miR-199a/b-3p as Therapeutic Target for Hepatocellular Carcinoma
- (2011) Jin Hou et al. CANCER CELL
- miR-198 inhibits migration and invasion of hepatocellular carcinoma cells by targeting the HGF/c-MET pathway
- (2011) Sheng Tan et al. FEBS LETTERS
- c-Met represents a potential therapeutic target for personalized treatment in hepatocellular carcinoma
- (2011) Hanning You et al. HEPATOLOGY
- Hepatocyte growth factor twenty years on: Much more than a growth factor
- (2011) Takahiro Nakamura et al. JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
- MicroRNA-199a-3p Is Downregulated in Human Osteosarcoma and Regulates Cell Proliferation and Migration
- (2011) Z. Duan et al. MOLECULAR CANCER THERAPEUTICS
- miR-122 activates hepatitis C virus translation by a specialized mechanism requiring particular RNA components
- (2011) Ashley P. E. Roberts et al. NUCLEIC ACIDS RESEARCH
- miR-199a-3p targets CD44 and reduces proliferation of CD44 positive hepatocellular carcinoma cell lines
- (2010) Jon C. Henry et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- miR-133b regulates the MET proto-oncogene and inhibits the growth of colorectal cancer cells in vitro and in vivo
- (2010) Gui Hu et al. CANCER BIOLOGY & THERAPY
- MiR-199a-3p Regulates mTOR and c-Met to Influence the Doxorubicin Sensitivity of Human Hepatocarcinoma Cells
- (2010) Francesca Fornari et al. CANCER RESEARCH
- Impact of Serum Hepatocyte Growth Factor on Treatment Response to Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors in Patients with Non-Small Cell Lung Adenocarcinoma
- (2010) K. Kasahara et al. CLINICAL CANCER RESEARCH
- A novel GSK-3 beta-C/EBP alpha-miR-122-insulin-like growth factor 1 receptor regulatory circuitry in human hepatocellular carcinoma
- (2010) Chunxian Zeng et al. HEPATOLOGY
- Signal transduction therapy of cancer
- (2010) Alexander Levitzki et al. MOLECULAR ASPECTS OF MEDICINE
- Targeting microRNAs in cancer: rationale, strategies and challenges
- (2010) Ramiro Garzon et al. NATURE REVIEWS DRUG DISCOVERY
- MET signalling: principles and functions in development, organ regeneration and cancer
- (2010) Livio Trusolino et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- MiR-122/Cyclin G1 Interaction Modulates p53 Activity and Affects Doxorubicin Sensitivity of Human Hepatocarcinoma Cells
- (2009) F. Fornari et al. CANCER RESEARCH
- Therapeutic microRNA Delivery Suppresses Tumorigenesis in a Murine Liver Cancer Model
- (2009) Janaiah Kota et al. CELL
- MicroRNAs: Target Recognition and Regulatory Functions
- (2009) David P. Bartel CELL
- The miR-34 family in cancer and apoptosis
- (2009) H Hermeking CELL DEATH AND DIFFERENTIATION
- Novel Therapeutic Inhibitors of the c-Met Signaling Pathway in Cancer
- (2009) J. P. Eder et al. CLINICAL CANCER RESEARCH
- Causes and consequences of microRNA dysregulation in cancer
- (2009) Carlo M. Croce NATURE REVIEWS GENETICS
- Loss of miR-122 expression in liver cancer correlates with suppression of the hepatic phenotype and gain of metastatic properties
- (2009) C Coulouarn et al. ONCOGENE
- Therapeutic Silencing of MicroRNA-122 in Primates with Chronic Hepatitis C Virus Infection
- (2009) R. E. Lanford et al. SCIENCE
- Regulation of hepatitis C virus by microRNA-122: Figure 1
- (2008) Catherine L. Jopling BIOCHEMICAL SOCIETY TRANSACTIONS
- Most mammalian mRNAs are conserved targets of microRNAs
- (2008) R. C. Friedman et al. GENOME RESEARCH
- MicroRNA-122, a tumor suppressor microRNA that regulates intrahepatic metastasis of hepatocellular carcinoma
- (2008) Wei-Chih Tsai et al. HEPATOLOGY
- MicroRNA profiling in hepatocellular tumors is associated with clinical features and oncogene/tumor suppressor gene mutations
- (2008) Yannick Ladeiro et al. HEPATOLOGY
- Inhibition of microRNA with antisense oligonucleotides
- (2007) Christine C. Esau METHODS
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now