MicroRNA-449a Is Downregulated in Non-Small Cell Lung Cancer and Inhibits Migration and Invasion by Targeting c-Met

miR-449a causes Rb-dependent cell cycle arrest and senescence in prostate cancer cells

(2015)   Oncotarget

MicroRNA-449a acts as a tumor suppressor in human bladder cancer through the regulation of pocket proteins

(2012) Hong Chen et al.   CANCER LETTERS

Histone Deacetylases Activate Hepatocyte Growth Factor Signaling by Repressing MicroRNA-449 in Hepatocellular Carcinoma Cells

(2012) Reena Buurman et al.   GASTROENTEROLOGY

MicroRNA-126 Inhibits Tumor Cell Growth and Its Expression Level Correlates with Poor Survival in Non-Small Cell Lung Cancer Patients

(2012) Jiyun Yang et al.   PLoS One

DNA hypermethylation of microRNA-34b/c has prognostic value for stage Ⅰ non-small cell lung cancer

(2011) Zhen Wang et al.   CANCER BIOLOGY & THERAPY

Frequent methylation and oncogenic role of microRNA-34b/c in small-cell lung cancer

(2011) Norimitsu Tanaka et al.   LUNG CANCER

Combining microRNA-449a/b with a HDAC inhibitor has a synergistic effect on growth arrest in lung cancer

(2011) Hyo Sung Jeon et al.   LUNG CANCER

miR-449 inhibits cell proliferation and is down-regulated in gastric cancer

(2011) Tony Bou Kheir et al.   Molecular Cancer

HGF/c-Met Overexpressions, but not Met Mutation, Correlates with Progression of Non-small Cell Lung Cancer

(2011) Mukaddes Gumustekin et al.   PATHOLOGY & ONCOLOGY RESEARCH

Hsa-miR-125a-3p and hsa-miR-125a-5p are downregulated in non-small cell lung cancer and have inverse effects on invasion and migration of lung cancer cells

(2010) Lili Jiang et al.   BMC CANCER

miR-449 regulates CDK-Rb-E2F1 through an auto-regulatory feedback circuit

(2010) Min Feng et al.   CELL CYCLE

MicroRNA Classifiers for Predicting Prognosis of Squamous Cell Lung Cancer

(2009) M. Raponi et al.   CANCER RESEARCH

miR-34a as a prognostic marker of relapse in surgically resected non-small-cell lung cancer

(2009) Elena Gallardo et al.   CARCINOGENESIS

E2F1-inducible microRNA 449a/b suppresses cell proliferation and promotes apoptosis

(2009) M Lizé et al.   CELL DEATH AND DIFFERENTIATION

miR-449a and miR-449b are direct transcriptional targets of E2F1 and negatively regulate pRb-E2F1 activity through a feedback loop by targeting CDK6 and CDC25A

(2009) X. Yang et al.   GENES & DEVELOPMENT

miR-449a targets HDAC-1 and induces growth arrest in prostate cancer

(2009) E J Noonan et al.   ONCOGENE

An expression meta-analysis of predicted microRNA targets identifies a diagnostic signature for lung cancer

(2008) Yu Liang   BMC Medical Genomics

MicroRNA Signature Predicts Survival and Relapse in Lung Cancer

(2008) Sung-Liang Yu et al.   CANCER CELL

Connecting microRNA Genes to the Core Transcriptional Regulatory Circuitry of Embryonic Stem Cells

(2008) Alexander Marson et al.   CELL

Chromatin structure analyses identify miRNA promoters

(2008) F. Ozsolak et al.   GENES & DEVELOPMENT