Melatonin limits paclitaxel-induced mitochondrial dysfunction in vitro and protects against paclitaxel-induced neuropathic pain in the rat

Inflammatory Pain Reduces C Fiber Activity-Dependent Slowing in a Sex-Dependent Manner, Amplifying Nociceptive Input to the Spinal Cord

(2017) Allen C. Dickie et al.   JOURNAL OF NEUROSCIENCE

Melatonin prevents mitochondrial dysfunction and promotes neuroprotection by inducing autophagy during oxaliplatin-evoked peripheral neuropathy

(2017) Aparna Areti et al.   JOURNAL OF PINEAL RESEARCH

Agomelatine

(2017) Chouki Chenaf et al.   PAIN

Paclitaxel-induced painful neuropathy is associated with changes in mitochondrial bioenergetics, glycolysis, and an energy deficit in dorsal root ganglia neurons

(2017) Natalie A. Duggett et al.   PAIN

MitoVitE, a mitochondria-targeted antioxidant, limits paclitaxel-induced oxidative stress and mitochondrial damage in vitro , and paclitaxel-induced mechanical hypersensitivity in a rat pain model

(2016) B. McCormick et al.   BRITISH JOURNAL OF ANAESTHESIA

α-Dendrotoxin-sensitive Kv1 channels contribute to conduction failure of polymodal nociceptive C-fibers from rat coccygeal nerve

(2016) Xiu-Chao Wang et al.   JOURNAL OF NEUROPHYSIOLOGY

Melatonin as an antioxidant: under promises but over delivers

(2016) Russel J. Reiter et al.   JOURNAL OF PINEAL RESEARCH

Melatonin synergizes the chemotherapeutic effect of 5-fluorouracil in colon cancer by suppressing PI3K/AKT and NF-κB/iNOS signaling pathways

(2016) Yue Gao et al.   JOURNAL OF PINEAL RESEARCH

Oxidative stress in the development, maintenance and resolution of paclitaxel-induced painful neuropathy

(2016) Natalie A. Duggett et al.   NEUROSCIENCE

Melatonin, an inhibitory agent in breast cancer

(2016) Elaheh Nooshinfar et al.   Breast Cancer

Melatonin prevents oxidative damage induced by maternal ethanol administration and reduces homocysteine in the cerebellum of rat pups

(2015) Farzaneh Bagheri et al.   BEHAVIOURAL BRAIN RESEARCH

The Safety of Melatonin in Humans

(2015) Lars Peter Holst Andersen et al.   CLINICAL DRUG INVESTIGATION

Melatonin ameliorates metabolic risk factors, modulates apoptotic proteins, and protects the rat heart against diabetes-induced apoptosis

(2015) Ali H. Amin et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Pharmacological Modulation of the Mitochondrial Electron Transport Chain in Paclitaxel-Induced Painful Peripheral Neuropathy

(2015) Lisa A. Griffiths et al.   JOURNAL OF PAIN

Doxorubicin resistance in breast cancer is driven by light at night-induced disruption of the circadian melatonin signal

(2015) Shulin Xiang et al.   JOURNAL OF PINEAL RESEARCH

Melatonergic system-based two-gene index is prognostic in human gliomas

(2015) Gabriela S. Kinker et al.   JOURNAL OF PINEAL RESEARCH

Pharmacotherapy for neuropathic pain in adults: a systematic review and meta-analysis

(2015) Nanna B Finnerup et al.   LANCET NEUROLOGY

Prevention of chemotherapy-induced peripheral neuropathy by the small-molecule inhibitor pifithrin-μ

(2015) Karen Krukowski et al.   PAIN

Identification of Mitochondria-Targeting Anticancer Compounds by an in Vitro Strategy

(2014) Xiang Zhang et al.   ANALYTICAL CHEMISTRY

Treatment with melatonin after status epilepticus attenuates seizure activity and neuronal damage but does not prevent the disturbance in diurnal rhythms and behavioral alterations in spontaneously hypertensive rats in kainate model of temporal lobe epilepsy

(2014) Zlatina Petkova et al.   EPILEPSY & BEHAVIOR

Melatonin does not modify the concentration of different metals in AβPP transgenic mice

(2014) Celeste Di Paolo et al.   FOOD AND CHEMICAL TOXICOLOGY

Melatonin as a potential therapy for sepsis: a phase I dose escalation study and an ex vivo whole blood model under conditions of sepsis

(2014) Helen F. Galley et al.   JOURNAL OF PINEAL RESEARCH

The Chemerin Receptor 23 Agonist, Chemerin, Attenuates Monosynaptic C-Fibre Input to Lamina I Neurokinin 1 Receptor Expressing Rat Spinal Cord Neurons in Inflammatory Pain

(2014) Allen C Dickie et al.   Molecular Pain

Incidence, prevalence, and predictors of chemotherapy-induced peripheral neuropathy: A systematic review and meta-analysis

(2014) Marta Seretny et al.   PAIN

Hyperexcitable C nociceptors in fibromyalgia

(2013) Jordi Serra et al.   ANNALS OF NEUROLOGY

Antioxidants that protect mitochondria reduce interleukin-6 and oxidative stress, improve mitochondrial function, and reduce biochemical markers of organ dysfunction in a rat model of acute sepsis

(2013) D.A. Lowes et al.   BRITISH JOURNAL OF ANAESTHESIA

Sex differences in pain: a brief review of clinical and experimental findings

(2013) E.J. Bartley et al.   BRITISH JOURNAL OF ANAESTHESIA

Effects of Agomelatine on Oxidative Stress in the Brain of Mice After Chemically Induced Seizures

(2013) Carlos Clayton Torres Aguiar et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Prophylactic treatment with melatonin after status epilepticus: Effects on epileptogenesis, neuronal damage, and behavioral changes in a kainate model of temporal lobe epilepsy

(2013) Jana Tchekalarova et al.   EPILEPSY & BEHAVIOR

Effect of Duloxetine on Pain, Function, and Quality of Life Among Patients With Chemotherapy-Induced Painful Peripheral Neuropathy

(2013) Ellen M. Lavoie Smith et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Combination pharmacotherapy for management of chronic pain: from bench to bedside

(2013) Ian Gilron et al.   LANCET NEUROLOGY

The efficacy and safety of melatonin in concurrent chemotherapy or radiotherapy for solid tumors: a meta-analysis of randomized controlled trials

(2012) Ye-min Wang et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Sex differences in pain and pain inhibition: multiple explanations of a controversial phenomenon

(2012) Jeffrey S. Mogil   NATURE REVIEWS NEUROSCIENCE

High spontaneous activity of C-nociceptors in painful polyneuropathy

(2012) Inge Petter Kleggetveit et al.   PAIN

Effects of mitochondrial poisons on the neuropathic pain produced by the chemotherapeutic agents, paclitaxel and oxaliplatin

(2012) Wen Hua Xiao et al.   PAIN

Melatonin and structurally similar compounds have differing effects on inflammation and mitochondrial function in endothelial cells under conditions mimicking sepsis

(2011) D.A. Lowes et al.   BRITISH JOURNAL OF ANAESTHESIA

Cytometric assessment of mitochondria using fluorescent probes

(2011) Cécile Cottet-Rousselle et al.   CYTOMETRY PART A

Inflammatory Pain Unmasks Heterosynaptic Facilitation in Lamina I Neurokinin 1 Receptor-Expressing Neurons in Rat Spinal Cord

(2011) C. Torsney   JOURNAL OF NEUROSCIENCE

The Melatonin MT1 Receptor Axis Modulates Mutant Huntingtin-Mediated Toxicity

(2011) X. Wang et al.   JOURNAL OF NEUROSCIENCE

Extrapineal melatonin: analysis of its subcellular distribution and daily fluctuations

(2011) Carmen Venegas et al.   JOURNAL OF PINEAL RESEARCH

Global Inhibition of Reactive Oxygen Species (ROS) Inhibits Paclitaxel-Induced Painful Peripheral Neuropathy

(2011) Mehmet Fidanboylu et al.   PLoS One

Chemotherapy-induced peripheral neurotoxicity

(2010) Guido Cavaletti et al.   Nature Reviews Neurology

Improving Bioscience Research Reporting: The ARRIVE Guidelines for Reporting Animal Research

(2010) Carol Kilkenny et al.   PLOS BIOLOGY

A method for measuring mitochondrial mass and activity

(2008) Maria Agnello et al.   CYTOTECHNOLOGY

Taxol-induced mitochondrial stress in melanoma cells is mediated by activation of c-Jun N-terminal kinase (JNK) and p38 pathways via uncoupling protein 2

(2007) Denis Selimovic et al.   CELLULAR SIGNALLING

Prevention of paclitaxel-evoked painful peripheral neuropathy by acetyl-l-carnitine: Effects on axonal mitochondria, sensory nerve fiber terminal arbors, and cutaneous Langerhans cells

(2007) Hai Wei Jin et al.   EXPERIMENTAL NEUROLOGY

Chemotherapy-evoked neuropathic pain: Abnormal spontaneous discharge in A-fiber and C-fiber primary afferent neurons and its suppression by acetyl-l-carnitine

(2007) Wen Hua Xiao et al.   PAIN