Sex differences in pain and pain inhibition: multiple explanations of a controversial phenomenon

Sex Differences in the Brain: The Not So Inconvenient Truth

(2012) M. M. McCarthy et al.   JOURNAL OF NEUROSCIENCE

Sex Differences in Reported Pain Across 11,000 Patients Captured in Electronic Medical Records

(2012) David Ruau et al.   JOURNAL OF PAIN

Genetically determined P2X7 receptor pore formation regulates variability in chronic pain sensitivity

(2012) Robert E Sorge et al.   NATURE MEDICINE

A systematic literature review of 10 years of research on sex/gender and pain perception – Part 2: Do biopsychosocial factors alter pain sensitivity differently in women and men?

(2012) Mélanie Racine et al.   PAIN

Characteristics of Response to Experimental Pain in Sexually Abused Women

(2011) Michal Granot et al.   CLINICAL JOURNAL OF PAIN

Sex-related differences in descending norepinephrine and serotonin controls of spinal withdrawal reflex during intramuscular saline induced muscle nociception in rats

(2011) Jing Lei et al.   EXPERIMENTAL NEUROLOGY

Sex Differences in Neuropeptide Content and Release from Rat Dental Pulp

(2011) Walter R. Bowles et al.   JOURNAL OF ENDODONTICS

Spinal Synthesis of Estrogen and Concomitant Signaling by Membrane Estrogen Receptors Regulate Spinal  - and  -Opioid Receptor Heterodimerization and Female-Specific Spinal Morphine Antinociception

(2011) N.-J. Liu et al.   JOURNAL OF NEUROSCIENCE

Spinal Cord Toll-Like Receptor 4 Mediates Inflammatory and Neuropathic Hypersensitivity in Male But Not Female Mice

(2011) R. E. Sorge et al.   JOURNAL OF NEUROSCIENCE

Nonopioid placebo analgesia is mediated by CB1 cannabinoid receptors

(2011) Fabrizio Benedetti et al.   NATURE MEDICINE

Pain sensitivity and vasopressin analgesia are mediated by a gene-sex-environment interaction

(2011) Jeffrey S Mogil et al.   NATURE NEUROSCIENCE

Sex similarities and differences in pain-related periaqueductal gray connectivity

(2011) Clas Linnman et al.   PAIN

A systematic literature review of 10 years of research on sex/gender and experimental pain perception – Part 1: Are there really differences between women and men?

(2011) Mélanie Racine et al.   PAIN

Individual Differences in Morphine and Butorphanol Analgesia: A Laboratory Pain Study

(2011) Kimberly T. Sibille et al.   PAIN MEDICINE

Perception of Thermal Pain and the Thermal Grill Illusion Is Associated with Polymorphisms in the Serotonin Transporter Gene

(2011) Fredrik Lindstedt et al.   PLoS One

Reference values of mechanical and thermal pain tests in a pain-free population

(2010) Alban Y. Neziril et al.   EUROPEAN JOURNAL OF PAIN

Sexual Dimorphism on Cytokines Expression in the Temporomandibular Joint: The Role of Gonadal Steroid Hormones

(2010) Karla E. Torres-Chávez et al.   INFLAMMATION

Endogenous ligands of TLR2 and TLR4: agonists or assistants?

(2010) Clett Erridge   JOURNAL OF LEUKOCYTE BIOLOGY

Varying Perceived Social Threat Modulates Pain Behavior in Male Mice

(2010) Dale J. Langford et al.   JOURNAL OF PAIN

Peripheral adenosine A2A receptors are involved in carrageenan-induced mechanical hyperalgesia in mice

(2010) L. Li et al.   NEUROSCIENCE

Sex bias in neuroscience and biomedical research

(2010) Annaliese K. Beery et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Sex-specificity and estrogen-dependence of kappa opioid receptor-mediated antinociception and antihyperalgesia

(2010) Kera P. Lawson et al.   PAIN

Do sex differences exist in opioid analgesia? A systematic review and meta-analysis of human experimental and clinical studies

(2010) Marieke Niesters et al.   PAIN

Gender differences in pain modulation by diffuse noxious inhibitory controls: A systematic review

(2010) Adriana Popescu et al.   PAIN

Progesterone rapidly recruits female-typical opioid-induced hyperalgesic mechanisms

(2010) Amanda R. Waxman et al.   PHYSIOLOGY & BEHAVIOR

Prenatal endotoxin exposure alters behavioural pain responses to lipopolysaccharide in adult offspring

(2010) Nicolette A. Hodyl et al.   PHYSIOLOGY & BEHAVIOR

Involvement of the Melanocortin-1 Receptor in Acute Pain and Pain of Inflammatory but Not Neuropathic Origin

(2010) Ada Delaney et al.   PLoS One

Formation of  -/ -opioid receptor heterodimer is sex-dependent and mediates female-specific opioid analgesia

(2010) S. Chakrabarti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sex-Specific Responses to Opiates: Animal and Human Studies

(2009) Albert Dahan et al.   ANESTHESIA AND ANALGESIA

Sex, Gender, and Pain: An Overview of a Complex Field

(2009) Robert W. Hurley et al.   ANESTHESIA AND ANALGESIA

Sex-specific Mediation of Opioid-induced Hyperalgesia by the Melanocortin-1 Receptor

(2009) Aaron Juni et al.   ANESTHESIOLOGY

The cAMP response element-binding protein in the bed nucleus of the stria terminalis modulates the formalin-induced pain behavior in the female rat

(2009) Hiroko Hagiwara et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Estradiol and testosterone differently affect visceral pain-related behavioural responses in male and female rats

(2009) Anna Maria Aloisi et al.   EUROPEAN JOURNAL OF PAIN

Ovarian hormones and pain response: A review of clinical and basic science studies

(2009) Vincent T. Martin   Gender Medicine

Sex, Gender, and Pain: A Review of Recent Clinical and Experimental Findings

(2009) Roger B. Fillingim et al.   JOURNAL OF PAIN

Sex differences in molecular neuroscience: from fruit flies to humans

(2009) Elena Jazin et al.   NATURE REVIEWS NEUROSCIENCE

Estrogen-dependent, sex-specific modulation of mustard oil-induced secondary thermal hyperalgesia by orphanin FQ in the rat

(2009) Jomo A. Claiborne et al.   NEUROSCIENCE LETTERS

Sex-Based Differences in Pain Perception and Treatment

(2009) Channing J. Paller et al.   PAIN MEDICINE

Social approach to pain in laboratory mice

(2009) Dale J. Langford et al.   Social Neuroscience

What does the “four core genotypes” mouse model tell us about sex differences in the brain and other tissues?

(2008) Arthur P. Arnold et al.   FRONTIERS IN NEUROENDOCRINOLOGY

Glial TLR4 receptor as new target to treat neuropathic pain: Efficacy of a new receptor antagonist in a model of peripheral nerve injury in mice

(2008) Isabella Bettoni et al.   GLIA

Sex Differences in  -Opioid Receptor Expression in the Rat Midbrain Periaqueductal Gray Are Essential for Eliciting Sex Differences in Morphine Analgesia

(2008) D. R. Loyd et al.   JOURNAL OF NEUROSCIENCE

Sex Chromosome Complement Affects Nociception and Analgesia in Newborn Mice

(2008) Laura Gioiosa et al.   JOURNAL OF PAIN

Sex differences in hyperalgesia during morphine infusion: Effect of gonadectomy and estrogen treatment

(2008) A JUNI et al.   NEUROPHARMACOLOGY

Pain-related effects of trait anger expression: Neural substrates and the role of endogenous opioid mechanisms

(2008) Stephen Bruehl et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Sex-specific pain modulation: The growth factor, neuregulin-1, as a pro-nociceptive cytokine

(2008) Michael L. LaCroix-Fralish   NEUROSCIENCE LETTERS

Sex chromosome complement affects nociception in tests of acute and chronic exposure to morphine in mice

(2007) Laura Gioiosa et al.   HORMONES AND BEHAVIOR