Lentivirus-mediated interleukin-1β (IL-1β) knock-down in the hippocampus alleviates lipopolysaccharide (LPS)-induced memory deficits and anxiety- and depression-like behaviors in mice

The wake-promoting drug Modafinil prevents motor impairment in sickness behavior induced by LPS in mice: Role for dopaminergic D1 receptor

(2018) Adriano Zager et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

L-F001, a novel multifunctional ROCK inhibitor, suppresses neuroinflammation in vitro and in vivo: Involvement of NF-κB inhibition and Nrf2 pathway activation

(2017) Jingkao Chen et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Resolvin D1 and D2 Reverse Lipopolysaccharide-Induced Depression-Like Behaviors Through the mTORC1 Signaling Pathway

(2017) Satoshi Deyama et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

The IL-1β phenomena in neuroinflammatory diseases

(2017) Andrew S. Mendiola et al.   JOURNAL OF NEURAL TRANSMISSION

IL-1β impairs retrograde flow of BDNF signaling by attenuating endosome trafficking

(2017) Anthony J. Carlos et al.   Journal of Neuroinflammation

Kososan, a Kampo medicine, prevents a social avoidance behavior and attenuates neuroinflammation in socially defeated mice

(2017) Naoki Ito et al.   Journal of Neuroinflammation

Activation of P2X7 receptor and NLRP3 inflammasome assembly in hippocampal glial cells mediates chronic stress-induced depressive-like behaviors

(2017) Na Yue et al.   Journal of Neuroinflammation

Neonatal Immune Challenge with Lipopolysaccharide Triggers Long-lasting Sex- and Age-related Behavioral and Immune/Neurotrophic Alterations in Mice: Relevance to Autism Spectrum Disorders

(2017) Charllyany Sabino Custódio et al.   MOLECULAR NEUROBIOLOGY

Translational evaluation of translocator protein as a marker of neuroinflammation in schizophrenia

(2017) T Notter et al.   MOLECULAR PSYCHIATRY

Gene deficiency and pharmacological inhibition of caspase-1 confers resilience to chronic social defeat stress via regulating the stability of surface AMPARs

(2017) M-X Li et al.   MOLECULAR PSYCHIATRY

The role of BDNF in Alzheimer's disease

(2017) Heikki Tanila   NEUROBIOLOGY OF DISEASE

Consequences of brain-derived neurotrophic factor withdrawal in CNS neurons and implications in disease

(2017) Abigail Mariga et al.   NEUROBIOLOGY OF DISEASE

Ketamine modulates hippocampal neurogenesis and pro-inflammatory cytokines but not stressor induced neurochemical changes

(2017) Melanie Clarke et al.   NEUROPHARMACOLOGY

Mast cells in neuroinflammation and brain disorders

(2017) Erik Hendriksen et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Tenuigenin down-regulates the release of nitric oxide, matrix metalloproteinase-9 and cytokines from lipopolysaccharide-stimulated microglia

(2017) Li Lu et al.   NEUROSCIENCE LETTERS

The opioid antagonist, β-funaltrexamine, inhibits lipopolysaccharide-induced neuroinflammation and reduces sickness behavior in mice

(2017) Randall L. Davis et al.   PHYSIOLOGY & BEHAVIOR

Nicotinamide mononucleotide attenuates brain injury after intracerebral hemorrhage by activating Nrf2/HO-1 signaling pathway

(2017) Chun-Chun Wei et al.   Scientific Reports

Propentofylline Prevents Sickness Behavior and Depressive-Like Behavior Induced by Lipopolysaccharide in Rats via Neuroinflammatory Pathway

(2017) Márcia M. T. Moraes et al.   PLoS One

BDNF DNA methylation changes as a biomarker of psychiatric disorders: literature review and open access database analysis

(2016) Galina Y. Zheleznyakova et al.   Behavioral and Brain Functions

Antidepressant effects of TBE-31 and MCE-1, the novel Nrf2 activators, in an inflammation model of depression

(2016) Wei Yao et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Lipopolysaccharide-Induced Behavioral Alterations Are Alleviated by Sodium Phenylbutyrate via Attenuation of Oxidative Stress and Neuroinflammatory Cascade

(2016) Ashok Jangra et al.   INFLAMMATION

Morin exerts cytoprotective effects against oxidative stress in C2C12 myoblasts via the upregulation of Nrf2-dependent HO-1 expression and the activation of the ERK pathway

(2016) Moon Hee Lee et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Aquaporin-4 Mediates the Suppressive Effect of Lipopolysaccharide on Hippocampal Neurogenesis

(2016) Rui Liang et al.   NEUROIMMUNOMODULATION

Antidepressant effects of combination of brexpiprazole and fluoxetine on depression-like behavior and dendritic changes in mice after inflammation

(2016) Min Ma et al.   PSYCHOPHARMACOLOGY

Osmotin attenuates LPS-induced neuroinflammation and memory impairments via the TLR4/NFκB signaling pathway

(2016) Haroon Badshah et al.   Scientific Reports

DISC1 regulates expression of the neurotrophin VGF through the PI3K/AKT/CREB pathway

(2015) Carmen Rodríguez-Seoane et al.   JOURNAL OF NEUROCHEMISTRY

Electroconvulsive seizures (ECS) do not prevent LPS-induced behavioral alterations and microglial activation

(2015) E. M. van Buel et al.   Journal of Neuroinflammation

Rodent models of neuroinflammation for Alzheimer’s disease

(2015) Amir Nazem et al.   Journal of Neuroinflammation

Neuroprotective effects of lycopene pretreatment on transient global cerebral ischemia-reperfusion in rats: The role of the Nrf2/HO-1 signaling pathway

(2015) XIAOFENG LEI et al.   Molecular Medicine Reports

BDNF Val66Met polymorphism and hippocampal volume in neuropsychiatric disorders: A systematic review and meta-analysis

(2015) F. Harrisberger et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Minocycline rescues decrease in neurogenesis, increase in microglia cytokines and deficits in sensorimotor gating in an animal model of schizophrenia

(2014) Daniele Mattei et al.   BRAIN BEHAVIOR AND IMMUNITY

Honokiol abrogates lipopolysaccharide-induced depressive like behavior by impeding neuroinflammation and oxido-nitrosative stress in mice

(2014) Kunjbihari Sulakhiya et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Etazolate abrogates the lipopolysaccharide (LPS)-induced downregulation of the cAMP/pCREB/BDNF signaling, neuroinflammatory response and depressive-like behavior in mice

(2014) J. Guo et al.   NEUROSCIENCE

The VGF-derived peptide TLQP62 produces antidepressant-like effects in mice via the BDNF/TrkB/CREB signaling pathway

(2014) Peipei Lin et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

The Neuropeptide VGF Is Reduced in Human Bipolar Postmortem Brain and Contributes to Some of the Behavioral and Molecular Effects of Lithium

(2013) S. Thakker-Varia et al.   JOURNAL OF NEUROSCIENCE

Intra-Hippocampal Transplantation of Neural Precursor Cells with Transgenic Over-Expression of IL-1 Receptor Antagonist Rescues Memory and Neurogenesis Impairments in an Alzheimer’s Disease Model

(2013) Ofra Ben-Menachem-Zidon et al.   NEUROPSYCHOPHARMACOLOGY

The role of neurotrophins in major depressive disorder

(2013) Cheng Jiang et al.   Translational Neuroscience

P2X7 Receptors: Channels, Pores and More

(2012) C. Volonte et al.   CNS & Neurological Disorders-Drug Targets

Brain-Derived Neurotrophic Factor-Dependent Synaptic Plasticity Is Suppressed by Interleukin-1  via p38 Mitogen-Activated Protein Kinase

(2012) L. Tong et al.   JOURNAL OF NEUROSCIENCE

Neuropeptides in depression: Role of VGF

(2008) Smita Thakker-Varia et al.   BEHAVIOURAL BRAIN RESEARCH

Interleukin-1 (IL-1): A central regulator of stress responses

(2008) Inbal Goshen et al.   FRONTIERS IN NEUROENDOCRINOLOGY

Lipopolysaccharide-induced depressive-like behavior is mediated by indoleamine 2,3-dioxygenase activation in mice

(2008) J C O'Connor et al.   MOLECULAR PSYCHIATRY

Influence of continuous infusion of interleukin-1β on depression-related processes in mice: corticosterone, circulating cytokines, brain monoamines, and cytokine mRNA expression

(2008) Hymie Anisman et al.   PSYCHOPHARMACOLOGY