Neutralization of interleukin-1β reduces cerebral edema and tissue loss and improves late cognitive outcome following traumatic brain injury in mice

Rapid Cerebral Amyloid Binding by Aβ Antibodies Infused into β-Amyloid Precursor Protein Transgenic Mice

(2010) David T. Winkler et al.   BIOLOGICAL PSYCHIATRY

Activated protein C analog with reduced anticoagulant activity improves functional recovery and reduces bleeding risk following controlled cortical impact

(2010) Corey T. Walker et al.   BRAIN RESEARCH

Appearance ofCxcl10-expressing cell clusters is common for traumatic brain injury and neurodegenerative disorders

(2010) Charlotte Israelsson et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Role of CCL2 (MCP-1) in Traumatic Brain Injury (TBI): Evidence from Severe TBI Patients and CCL2−/− Mice

(2010) Bridgette D Semple et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

The Cytokine Response to Human Traumatic Brain Injury: Temporal Profiles and Evidence for Cerebral Parenchymal Production

(2010) Adel Helmy et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Differences in Cerebral Extracellular Response of Interleukin-1β, Interleukin-6, and Interleukin-10 After Subarachnoid Hemorrhage or Severe Head Trauma in Humans

(2010) Pekka. Mellergård et al.   NEUROSURGERY

Involvement of pro- and anti-inflammatory cytokines and chemokines in the pathophysiology of traumatic brain injury

(2010) Jenna M. Ziebell et al.   Neurotherapeutics

Sustained hippocampal IL-1β overexpression impairs contextual and spatial memory in transgenic mice

(2009) Amy M. Hein et al.   BRAIN BEHAVIOR AND IMMUNITY

Minocycline effects on cerebral edema: Relations with inflammatory and oxidative stress markers following traumatic brain injury in mice

(2009) Shadi Homsi et al.   BRAIN RESEARCH

Neutralization of interleukin-1β modifies the inflammatory response and improves histological and cognitive outcome following traumatic brain injury in mice

(2009) Fredrik Clausen et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

A Rapid and Transient Peripheral Inflammatory Response Precedes Brain Inflammation after Experimental Stroke

(2009) Katie Z Chapman et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Effects of monocyte chemoattractant protein 1 on blood-borne cell recruitment after transient focal cerebral ischemia in mice

(2009) M. Schilling et al.   NEUROSCIENCE

Sustained expression of interleukin-1β in mouse hippocampus impairs spatial memory

(2009) A.H. Moore et al.   NEUROSCIENCE

CHANGES IN EXTRACELLULAR CONCENTRATIONS OF SOME CYTOKINES, CHEMOKINES, AND NEUROTROPHIC FACTORS AFTER INSERTION OF INTRACEREBRAL MICRODIALYSIS CATHETERS IN NEUROSURGICAL PATIENTS

(2009) Pekka Mellergård et al.   NEUROSURGERY

Activated Protein C is Neuroprotective and Mediates New Blood Vessel Formation and Neurogenesis After Controlled Cortical Impact

(2009) Anthony L. Petraglia et al.   NEUROSURGERY

Role of Interleukin-1β in Early Brain Injury After Subarachnoid Hemorrhage in Mice

(2009) Takumi Sozen et al.   STROKE

Cerebral microdialysis of interleukin (IL)-1ß and IL-6: extraction efficiency and production in the acute phase after severe traumatic brain injury in rats

(2008) Hedy Folkersma et al.   ACTA NEUROCHIRURGICA

Cell-specific and concentration-dependent actions of interleukin-1 in acute brain inflammation

(2008) Emmanuel Pinteaux et al.   CYTOKINE

Systemic inflammation exacerbates behavioral and histopathological consequences of isolated traumatic brain injury in rats

(2008) Akira Utagawa et al.   EXPERIMENTAL NEUROLOGY

Exacerbated glial response in the aged mouse hippocampus following controlled cortical impact injury

(2008) Rajat Sandhir et al.   EXPERIMENTAL NEUROLOGY

Interleukin-1β: a bridge between inflammation and excitotoxicity?

(2008) Birgit Fogal et al.   JOURNAL OF NEUROCHEMISTRY

Suppression of acute proinflammatory cytokine and chemokine upregulation by post-injury administration of a novel small molecule improves long-term neurologic outcome in a mouse model of traumatic brain injury

(2008) Eric Lloyd et al.   Journal of Neuroinflammation

Systemic Inflammation Alters the Kinetics of Cerebrovascular Tight Junction Disruption after Experimental Stroke in Mice

(2008) B. W. McColl et al.   JOURNAL OF NEUROSCIENCE

Distinct Cellular Patterns of Upregulated Chemokine Expression Supporting a Prominent Inflammatory Role in Traumatic Brain Injury

(2008) Charlotte Israelsson et al.   JOURNAL OF NEUROTRAUMA

Moderate and severe traumatic brain injury in adults

(2008) Andrew IR Maas et al.   LANCET NEUROLOGY

Intra-peritoneal Injection of Polyclonal Anti-Interferon Alpha Antibodies Cross the Blood Brain Barrier and Neutralize Interferon Alpha

(2008) A. Sas et al.   NEUROCHEMICAL RESEARCH

The human anti-IL-1β monoclonal antibody ACZ885 is effective in joint inflammation models in mice and in a proof-of-concept study in patients with rheumatoid arthritis

(2008) Rieke Alten et al.   ARTHRITIS RESEARCH & THERAPY

Matrix metalloproteinase-9 and urokinase plasminogen activator mediate interleukin-1-induced neurotoxicity

(2007) Peter Thornton et al.   MOLECULAR AND CELLULAR NEUROSCIENCE