Safety assessment of nanomaterials using an advanced decision-making framework, the DF4nanoGrouping

Airborne engineered nanomaterials in the workplace—a review of release and worker exposure during nanomaterial production and handling processes

(2017) Yaobo Ding et al.   JOURNAL OF HAZARDOUS MATERIALS

Concern-driven integrated approaches for the grouping, testing and assessment of nanomaterials

(2016) Robert Landsiedel   ENVIRONMENTAL POLLUTION

Influence of pH, particle size and crystal form on dissolution behaviour of engineered nanomaterials

(2016) M.-L. Avramescu et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Exploring the effect of silver nanoparticle size and medium composition on uptake into pulmonary epithelial 16HBE14o-cells

(2016) Katja Kettler et al.   JOURNAL OF NANOPARTICLE RESEARCH

Inhalation TTC values: A new integrative grouping approach considering structural, toxicological and mechanistic features

(2016) I. Tluczkiewicz et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Case studies putting the decision-making framework for the grouping and testing of nanomaterials (DF4nanoGrouping) into practice

(2016) Josje H.E. Arts et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Towards a nanospecific approach for risk assessment

(2016) Susan Dekkers et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Framework to Evaluate Exposure Relevance and Data Needs for Risk Assessment of Nanomaterials usingin VitroTesting Strategies

(2016) Monita Sharma et al.   RISK ANALYSIS

Grouping nanomaterials to predict their potential to induce pulmonary inflammation

(2016) Hedwig M. Braakhuis et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

An in vitro alveolar macrophage assay for predicting the short-term inhalation toxicity of nanomaterials

(2016) Martin Wiemann et al.   JOURNAL OF NANOBIOTECHNOLOGY

Nanomaterial Categorization for Assessing Risk Potential To Facilitate Regulatory Decision-Making

(2015) Hilary Godwin et al.   ACS Nano

Where Are We Heading in Nanotechnology Environmental Health and Safety and Materials Characterization?

(2015) Andre E. Nel et al.   ACS Nano

Industrial applications of nanoparticles

(2015) W. J. Stark et al.   CHEMICAL SOCIETY REVIEWS

In vitro and in vivo genotoxicity investigations of differently sized amorphous SiO2 nanomaterials

(2015) Elena Maser et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Translational toxicology in setting occupational exposure limits for dusts and hazard classification – a critical evaluation of a recent approach to translate dust overload findings from rats to humans

(2015) Peter Morfeld et al.   Particle and Fibre Toxicology

Eye irritation testing of nanomaterials using the EpiOcular™ eye irritation test and the bovine corneal opacity and permeability assay

(2015) Susanne N. Kolle et al.   Particle and Fibre Toxicology

Epoxy composite dusts with and without carbon nanotubes cause similar pulmonary responses, but differences in liver histology in mice following pulmonary deposition

(2015) Anne Thoustrup Saber et al.   Particle and Fibre Toxicology

Comparative assessment of nanomaterial definitions and safety evaluation considerations

(2015) Darrell R. Boverhof et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

A decision-making framework for the grouping and testing of nanomaterials (DF4nanoGrouping)

(2015) Josje H.E. Arts et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Oral two-generation reproduction toxicity study with NM-200 synthetic amorphous silica in Wistar rats

(2015) André Wolterbeek et al.   REPRODUCTIVE TOXICOLOGY

Prenatal toxicity of synthetic amorphous silica nanomaterial in rats

(2015) Thomas Hofmann et al.   REPRODUCTIVE TOXICOLOGY

How safe are nanomaterials?

(2015) E. Valsami-Jones et al.   SCIENCE

Towards sensible toxicity testing for nanomaterials: proposal for the specification of test design

(2015) Annegret Potthoff et al.   SCIENCE AND TECHNOLOGY OF ADVANCED MATERIALS

Toxicity testing in the 21st century beyond environmental chemicals

(2015) Costanza Rovida   ALTEX-Alternatives to Animal Experimentation

The MARINA Risk Assessment Strategy: A Flexible Strategy for Efficient Information Collection and Risk Assessment of Nanomaterials

(2015) Peter Bos et al.   International Journal of Environmental Research and Public Health

Grouping and Read-Across Approaches for Risk Assessment of Nanomaterials

(2015) Agnes Oomen et al.   International Journal of Environmental Research and Public Health

Conceptual Questions and Challenges Associated with the Traditional Risk Assessment Paradigm for Nanomaterials

(2015) Jutta Jahnel   NanoEthics

Effects of SiO2, ZrO2, and BaSO4 nanomaterials with or without surface functionalization upon 28-day oral exposure to rats

(2014) Roland Buesen et al.   ARCHIVES OF TOXICOLOGY

Manufactured nanomaterials: categorization and approaches to hazard assessment

(2014) Thomas Gebel et al.   ARCHIVES OF TOXICOLOGY

Toxic response of graphene nanoplatelets in vivo and in vitro

(2014) Eun-Jung Park et al.   ARCHIVES OF TOXICOLOGY

Time course of lung retention and toxicity of inhaled particles: short-term exposure to nano-Ceria

(2014) Jana Keller et al.   ARCHIVES OF TOXICOLOGY

Granular biodurable nanomaterials: No convincing evidence for systemic toxicity

(2014) Marcus Moreno-Horn et al.   CRITICAL REVIEWS IN TOXICOLOGY

A strategy for grouping of nanomaterials based on key physico-chemical descriptors as a basis for safer-by-design NMs

(2014) Iseult Lynch et al.   Nano Today

Pulmonary toxicity of nanomaterials: a critical comparison of published in vitro assays and in vivo inhalation or instillation studies

(2014) Robert Landsiedel et al.   Nanomedicine

Derivation of occupational exposure levels (OELs) of Low-toxicity isometric biopersistent particles: how can the kinetic lung overload paradigm be used for improved inhalation toxicity study design and OEL-derivation?

(2014) Jürgen Pauluhn   Particle and Fibre Toxicology

Biokinetics and effects of barium sulfate nanoparticles

(2014) Nagarjun Konduru et al.   Particle and Fibre Toxicology

Application of short-term inhalation studies to assess the inhalation toxicity of nanomaterials

(2014) Robert Landsiedel et al.   Particle and Fibre Toxicology

ITS-NANO - Prioritising nanosafety research to develop a stakeholder driven intelligent testing strategy

(2014) Vicki Stone et al.   Particle and Fibre Toxicology

A critical appraisal of existing concepts for the grouping of nanomaterials

(2014) Josje H.E. Arts et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

The yin: an adverse health perspective of nanoceria: uptake, distribution, accumulation, and mechanisms of its toxicity

(2014) Robert A. Yokel et al.   Environmental Science-Nano

Genotoxicity of nanomaterials: Refining strategies and tests for hazard identification

(2013) Stefan Pfuhler et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Improving the Human Hazard Characterization of Chemicals: A Tox21 Update

(2013) Raymond R. Tice et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Principal component and causal analysis of structural and acutein vitrotoxicity data for nanoparticles

(2013) Xue Z. Wang et al.   Nanotoxicology

Concern-driven integrated approaches to nanomaterial testing and assessment – report of the NanoSafety Cluster Working Group 10

(2013) Agnes G. Oomen et al.   Nanotoxicology

Predictive value of in vitro assays depends on the mechanism of toxicity of metal oxide nanoparticles

(2013) Wan-Seob Cho et al.   Particle and Fibre Toxicology

Predictive Toxicology of cobalt ferrite nanoparticles: comparative in-vitro study of different cellular models using methods of knowledge discovery from data

(2013) Limor Horev-Azaria et al.   Particle and Fibre Toxicology

Comparative inhalation toxicity of multi-wall carbon nanotubes, graphene, graphite nanoplatelets and low surface carbon black

(2013) Lan Ma-Hock et al.   Particle and Fibre Toxicology

Additional Histopathologic Examination of the Lungs from a 3-Month Inhalation Toxicity Study with Multiwall Carbon Nanotubes in Rats

(2013) Silke Treumann et al.   TOXICOLOGICAL SCIENCES

Nanomaterial Toxicity Testing in the 21st Century: Use of a Predictive Toxicological Approach and High-Throughput Screening

(2012) Andre Nel et al.   ACCOUNTS OF CHEMICAL RESEARCH

The Effect of Nanoparticle Size, Shape, and Surface Chemistry on Biological Systems

(2012) Alexandre Albanese et al.   Annual Review of Biomedical Engineering

Hazard identification of inhaled nanomaterials: making use of short-term inhalation studies

(2012) Christoph L. Klein et al.   ARCHIVES OF TOXICOLOGY

Nanostructured calcium silicate hydrate seeds accelerate concrete hardening: a combined assessment of benefits and risks

(2012) Michael Bräu et al.   ARCHIVES OF TOXICOLOGY

Genotoxicity investigations on nanomaterials

(2012) Franz Oesch et al.   ARCHIVES OF TOXICOLOGY

Toxico-/biokinetics of nanomaterials

(2012) Robert Landsiedel et al.   ARCHIVES OF TOXICOLOGY

Small difference in carcinogenic potency between GBP nanomaterials and GBP micromaterials

(2012) Thomas Gebel   ARCHIVES OF TOXICOLOGY

Deposition behavior of inhaled nanostructured TiO2in rats: fractions of particle diameter below 100 nm (nanoscale) and the slicing bias of transmission electron microscopy

(2012) Peter Morfeld et al.   INHALATION TOXICOLOGY

Short-Term Rat Inhalation Study With Aerosols of Acrylic Ester-Based Polymer Dispersions Containing a Fraction of Nanoparticles

(2012) Lan Ma-Hock et al.   INTERNATIONAL JOURNAL OF TOXICOLOGY

Development of risk-based nanomaterial groups for occupational exposure control

(2012) E. D. Kuempel et al.   JOURNAL OF NANOPARTICLE RESEARCH

Autophagy and lysosomal dysfunction as emerging mechanisms of nanomaterial toxicity

(2012) Stephan T Stern et al.   Particle and Fibre Toxicology

Inhalation studies for the safety assessment of nanomaterials: status quo and the way forward

(2012) Robert Landsiedel et al.   Wiley Interdisciplinary Reviews-Nanomedicine and Nanobiotechnology

Cytotoxicity screening of 23 engineered nanomaterials using a test matrix of ten cell lines and three different assays

(2011) Alexandra Kroll et al.   Particle and Fibre Toxicology

On the Lifecycle of Nanocomposites: Comparing Released Fragments and their In-Vivo Hazards from Three Release Mechanisms and Four Nanocomposites

(2011) Wendel Wohlleben et al.   Small

Safety Evaluation of Sunscreen Formulations Containing Titanium Dioxide and Zinc Oxide Nanoparticles in UVB Sunburned Skin: An In Vitro and In Vivo Study

(2011) N. A. Monteiro-Riviere et al.   TOXICOLOGICAL SCIENCES

Toward toxicity testing of nanomaterials in the 21st century: a paradigm for moving forward

(2011) David Y. Lai   Wiley Interdisciplinary Reviews-Nanomedicine and Nanobiotechnology

Testing Metal-Oxide Nanomaterials for Human Safety

(2010) Robert Landsiedel et al.   ADVANCED MATERIALS

Adverse outcome pathways: A conceptual framework to support ecotoxicology research and risk assessment

(2010) Gerald T. Ankley et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

The carcinogenic potential of nanomaterials, their release from products and options for regulating them

(2010) Heidi Becker et al.   INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH

Rapid translocation of nanoparticles from the lung airspaces to the body

(2010) Hak Soo Choi et al.   NATURE BIOTECHNOLOGY

ISDD: A computational model of particle sedimentation, diffusion and target cell dosimetry for in vitro toxicity studies

(2010) Paul M Hinderliter et al.   Particle and Fibre Toxicology

Inhalation Toxicity of Multiwall Carbon Nanotubes in Rats Exposed for 3 Months

(2009) Lan Ma-Hock et al.   TOXICOLOGICAL SCIENCES

Development of a Short-Term Inhalation Test in the Rat Using Nano-Titanium Dioxide as a Model Substance

(2008) Lan Ma-Hock et al.   INHALATION TOXICOLOGY

Genotoxicity investigations on nanomaterials: Methods, preparation and characterization of test material, potential artifacts and limitations—Many questions, some answers

(2008) Robert Landsiedel et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

Toxicity Testing in the 21st Century: Implications for Human Health Risk Assessment

(2008) Daniel Krewski et al.   RISK ANALYSIS

Limitations and relative utility of screening assays to assess engineered nanoparticle toxicity in a human cell line

(2008) N.A. Monteiro-Riviere et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY