Predictive value of in vitro assays depends on the mechanism of toxicity of metal oxide nanoparticles

The Biologically Effective Dose in Inhalation Nanotoxicology

(2012) Ken Donaldson et al.   ACCOUNTS OF CHEMICAL RESEARCH

Inorganic nanoparticle biomolecular corona: formation, evolution and biological impact

(2012) Eudald Casals et al.   Nanomedicine

Zeta Potential and Solubility to Toxic Ions as Mechanisms of Lung Inflammation Caused by Metal/Metal Oxide Nanoparticles

(2012) Wan-Seob Cho et al.   TOXICOLOGICAL SCIENCES

NiO and Co3O4 nanoparticles induce lung DTH-like responses and alveolar lipoproteinosis

(2011) W.-S. Cho et al.   EUROPEAN RESPIRATORY JOURNAL

Aggregation and Dissolution of 4 nm ZnO Nanoparticles in Aqueous Environments: Influence of pH, Ionic Strength, Size, and Adsorption of Humic Acid

(2011) Shao-Wei Bian et al.   LANGMUIR

Differential pro-inflammatory effects of metal oxide nanoparticles and their soluble ionsin vitroandin vivo; zinc and copper nanoparticles, but not their ions, recruit eosinophils to the lungs

(2011) Wan-Seob Cho et al.   Nanotoxicology

Cytotoxicity screening of 23 engineered nanomaterials using a test matrix of ten cell lines and three different assays

(2011) Alexandra Kroll et al.   Particle and Fibre Toxicology

Effects of Cell Culture Media on the Dynamic Formation of Protein−Nanoparticle Complexes and Influence on the Cellular Response

(2010) Gabriele Maiorano et al.   ACS Nano

A review of the in vivo and in vitro toxicity of silver and gold particulates: Particle attributes and biological mechanisms responsible for the observed toxicity

(2010) Helinor J. Johnston et al.   CRITICAL REVIEWS IN TOXICOLOGY

Metal Oxide Nanoparticles Induce Unique Inflammatory Footprints in the Lung: Important Implications for Nanoparticle Testing

(2010) Wan-Seob Cho et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Physico-chemical features of engineered nanoparticles relevant to their toxicity

(2010) Bice Fubini et al.   Nanotoxicology

Nanomaterial cytotoxicity is composition, size, and cell type dependent

(2010) Syed K Sohaebuddin et al.   Particle and Fibre Toxicology

Nanoparticles activate the NLR pyrin domain containing 3 (Nlrp3) inflammasome and cause pulmonary inflammation through release of IL-1  and IL-1 

(2010) A. S. Yazdi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nanoparticle cytotoxicity depends on intracellular solubility: Comparison of stabilized copper metal and degradable copper oxide nanoparticles

(2010) Andreas M. Studer et al.   TOXICOLOGY LETTERS

Ultrafine NiO Particles Induce Cytotoxicity in Vitro by Cellular Uptake and Subsequent Ni(II) Release

(2009) Masanori Horie et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Pathological features of different sizes of nickel oxide following intratracheal instillation in rats

(2009) Akira Ogami et al.   INHALATION TOXICOLOGY

Understanding biophysicochemical interactions at the nano–bio interface

(2009) Andre E. Nel et al.   NATURE MATERIALS

The limits of testing particle-mediated oxidative stress in vitro in predicting diverse pathologies; relevance for testing of nanoparticles

(2009) Ken Donaldson et al.   Particle and Fibre Toxicology

Current in vitro methods in nanoparticle risk assessment: Limitations and challenges

(2008) Alexandra Kroll et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Co-cultures of multiple cell types mimic pulmonary cell communication in response to urban PM10

(2008) E. Alfaro-Moreno et al.   EUROPEAN RESPIRATORY JOURNAL

Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

(2008) Veit Hornung et al.   NATURE IMMUNOLOGY

Particle-Induced Cytokine Responses in Cardiac Cell Cultures—the Effect of Particles versus Soluble Mediators Released by Particle-Exposed Lung Cells

(2008) Annike I. Totlandsdal et al.   TOXICOLOGICAL SCIENCES