The role for gut permeability in the pathogenesis of type 1 diabetes - a solid or leaky concept?

Alterations in Intestinal Microbiota Correlate With Susceptibility to Type 1 Diabetes

(2015) Aimon K. Alkanani et al.   DIABETES

Role of the gastrointestinal ecosystem in the development of type 1 diabetes

(2015) Joseph G Daft et al.   PEDIATRIC DIABETES

Maternal Antibiotic-Induced Early Changes in Microbial Colonization Selectively Modulate Colonic Permeability and Inducible Heat Shock Proteins, and Digesta Concentrations of Alkaline Phosphatase and TLR-Stimulants in Swine Offspring

(2015) Marie-Edith Arnal et al.   PLoS One

A Maternal Gluten-Free Diet Reduces Inflammation and Diabetes Incidence in the Offspring of NOD Mice

(2014) C. H. F. Hansen et al.   DIABETES

Hydrolyzed Infant Formula and Early β-Cell Autoimmunity

(2014) Mikael Knip et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Maternal obesity induces gut inflammation and impairs gut epithelial barrier function in nonobese diabetic mice

(2014) Yansong Xue et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Minireview: Gut Microbiota: The Neglected Endocrine Organ

(2014) Gerard Clarke et al.   MOLECULAR ENDOCRINOLOGY

Oral Supplementation with Non-Absorbable Antibiotics or Curcumin Attenuates Western Diet-Induced Atherosclerosis and Glucose Intolerance in LDLR−/− Mice – Role of Intestinal Permeability and Macrophage Activation

(2014) Siddhartha S. Ghosh et al.   PLoS One

From Intestinal Permeability to Dysmotility: The Biobreeding Rat as a Model for Functional Gastrointestinal Disorders

(2014) Tim Vanuytsel et al.   PLoS One

Fecal Biomarkers of Intestinal Health and Disease in Children

(2014) Tamara Pang et al.   Frontiers in Pediatrics

Promotion of Autoimmune Diabetes by Cereal Diet in the Presence or Absence of Microbes Associated With Gut Immune Activation, Regulatory Imbalance, and Altered Cathelicidin Antimicrobial Peptide

(2013) C. Patrick et al.   DIABETES

Increased intestinal permeability to oral chromium (51Cr)-EDTA in human Type 2 diabetes

(2013) F. Horton et al.   DIABETIC MEDICINE

Increased circulatory levels of lipopolysaccharide (LPS) and zonulin signify novel biomarkers of proinflammation in patients with type 2 diabetes

(2013) B. Jayashree et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Gastrointestinal Motility Changes and Myenteric Plexus Alterations in Spontaneously Diabetic Biobreeding Rats

(2013) Ingrid Demedts et al.   Journal of Neurogastroenterology and Motility

Intestinal Permeability and Its Regulation by Zonulin: Diagnostic and Therapeutic Implications

(2012) Alessio Fasano   Clinical Gastroenterology and Hepatology

Fecal Microbiota Composition Differs Between Children With  -Cell Autoimmunity and Those Without

(2012) M. C. de Goffau et al.   DIABETES

Type 1 Diabetes Is Associated With Enterovirus Infection in Gut Mucosa

(2012) M. Oikarinen et al.   DIABETES

Potential mechanisms explaining why hydrolyzed casein-based diets outclass single amino acid-based diets in the prevention of autoimmune diabetes in diabetes-prone BB rats

(2012) J. T. J. Visser et al.   DIABETES-METABOLISM RESEARCH AND REVIEWS

Does the gut microbiota have a role in type 1 diabetes? Early evidence from humans and animal models of the disease

(2012) M. A. Atkinson et al.   DIABETOLOGIA

No evidence of enteroviruses in the intestine of patients with type 1 diabetes

(2012) A. Mercalli et al.   DIABETOLOGIA

Is the origin of type 1 diabetes in the gut?

(2012) Outi Vaarala   IMMUNOLOGY AND CELL BIOLOGY

Celiac disease in patients with type 1 diabetes: a condition with distinct changes in intestinal immunity?

(2011) Raivo Uibo et al.   Cellular & Molecular Immunology

Leaky Gut and Autoimmune Diseases

(2011) Alessio Fasano   CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY

Antidiabetic Actions of Endogenous and Exogenous GLP-1 in Type 1 Diabetic Patients With and Without Residual  -Cell Function

(2011) U. Kielgast et al.   DIABETES

Four Weeks of Treatment With Liraglutide Reduces Insulin Dose Without Loss of Glycemic Control in Type 1 Diabetic Patients With and Without Residual  -Cell Function

(2011) U. Kielgast et al.   DIABETES CARE

Primary Dietary Intervention Study to Reduce the Risk of Islet Autoimmunity in Children at Increased Risk for Type 1 Diabetes: The BABYDIET study

(2011) S. Hummel et al.   DIABETES CARE

Leaky gut and diabetes mellitus: what is the link?

(2011) S. de Kort et al.   Obesity Reviews

Zonulin and Its Regulation of Intestinal Barrier Function: The Biological Door to Inflammation, Autoimmunity, and Cancer

(2011) Alessio Fasano   PHYSIOLOGICAL REVIEWS

Non-Invasive Markers for Early Diagnosis and Determination of the Severity of Necrotizing Enterocolitis

(2010) Geertje Thuijls et al.   ANNALS OF SURGERY

Restoration of impaired intestinal barrier function by the hydrolysed casein diet contributes to the prevention of type 1 diabetes in the diabetes-prone BioBreeding rat

(2010) J. T. J. Visser et al.   DIABETOLOGIA

Butyrate and Type 1 Diabetes Mellitus: Can We Fix the Intestinal Leak?

(2010) Nan Li et al.   JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION

Dietary Intervention in Infancy and Later Signs of Beta-Cell Autoimmunity

(2010) Mikael Knip et al.   NEW ENGLAND JOURNAL OF MEDICINE

Gut barrier disruption by an enteric bacterial pathogen accelerates insulitis in NOD mice

(2009) A. S. Lee et al.   DIABETOLOGIA

Changes in gut microbiota control inflammation in obese mice through a mechanism involving GLP-2-driven improvement of gut permeability

(2009) P. D. Cani et al.   GUT

Leaking gut in type 1 diabetes

(2008) Outi Vaarala   CURRENT OPINION IN GASTROENTEROLOGY

The "Perfect Storm" for Type 1 Diabetes: The Complex Interplay Between Intestinal Microbiota, Gut Permeability, and Mucosal Immunity

(2008) O. Vaarala et al.   DIABETES

Glucagon-Like Peptide-2 Reduces Intestinal Permeability But Does Not Modify the Onset of Type 1 Diabetes in the Nonobese Diabetic Mouse

(2008) Irene Hadjiyanni et al.   ENDOCRINOLOGY

Innate immunity and intestinal microbiota in the development of Type 1 diabetes

(2008) Li Wen et al.   NATURE