A Genomic Approach to Human Autoimmune Diseases

Identification of a Molecular Signature in Human Type 1 Diabetes Mellitus Using Serum and Functional Genomics

(2014) X. Wang et al.   JOURNAL OF IMMUNOLOGY

Neutralization of interferon-α/β-inducible genes and downstream effect in a phase I trial of an anti-interferon-α monoclonal antibody in systemic lupus erythematosus

(2009) Yihong Yao et al.   ARTHRITIS AND RHEUMATISM

Subtype-specific peripheral blood gene expression profiles in recent-onset juvenile idiopathic arthritis

(2009) Michael G. Barnes et al.   ARTHRITIS AND RHEUMATISM

The myeloid-related proteins 8 and 14 complex, a novel ligand of toll-like receptor 4, and interleukin-1β form a positive feedback mechanism in systemic-onset juvenile idiopathic arthritis

(2009) Michael Frosch et al.   ARTHRITIS AND RHEUMATISM

Gene expression profiling of whole blood: Comparison of target preparation methods for accurate and reproducible microarray analysis

(2009) Kristina Vartanian et al.   BMC GENOMICS

Gene Expression Signatures Diagnose Influenza and Other Symptomatic Respiratory Viral Infections in Humans

(2009) Aimee K. Zaas et al.   Cell Host & Microbe

Sustained Effects of Interleukin-1 Receptor Antagonist Treatment in Type 2 Diabetes

(2009) C. M. Larsen et al.   DIABETES CARE

Peripheral blood gene expression profiling in Sjögren's syndrome

(2009) E S Emamian et al.   GENES AND IMMUNITY

Identification of new SLE-associated genes with a two-step Bayesian study design

(2009) D L Armstrong et al.   GENES AND IMMUNITY

Molecular subtypes of systemic sclerosis in association with anti-centromere antibodies and digital ulcers

(2009) C L Bos et al.   GENES AND IMMUNITY

Recent insights into the genetic basis of systemic lupus erythematosus

(2009) K L Moser et al.   GENES AND IMMUNITY

The STAT4 gene influences the genetic predisposition to systemic sclerosis phenotype

(2009) B. Rueda et al.   HUMAN MOLECULAR GENETICS

Self-RNA–antimicrobial peptide complexes activate human dendritic cells through TLR7 and TLR8

(2009) Dipyaman Ganguly et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Gene Transcript Abundance Profiles Distinguish Kawasaki Disease from Adenovirus Infection

(2009) Stephen J. Popper et al.   JOURNAL OF INFECTIOUS DISEASES

Anakinra for Rheumatoid Arthritis: A Systematic Review

(2009) M. MERTENS et al.   JOURNAL OF RHEUMATOLOGY

Personal phenotypes to go with personal genomes

(2009) Michael Snyder et al.   Molecular Systems Biology

Navigating the network: signaling cross-talk in hematopoietic cells

(2009) Iain D C Fraser et al.   NATURE IMMUNOLOGY

Mapping complex disease traits with global gene expression

(2009) William Cookson et al.   NATURE REVIEWS GENETICS

Gene-expression profiling in rheumatic disease: tools and therapeutic potential

(2009) Jason W. Bauer et al.   Nature Reviews Rheumatology

Gene-Expression Signatures in Breast Cancer

(2009) Christos Sotiriou et al.   NEW ENGLAND JOURNAL OF MEDICINE

Scleroderma

(2009) Armando Gabrielli et al.   NEW ENGLAND JOURNAL OF MEDICINE

Longitudinal system-based analysis of transcriptional responses to type I interferons

(2009) D. J. Pappas et al.   PHYSIOLOGICAL GENOMICS

A Practical Platform for Blood Biomarker Study by Using Global Gene Expression Profiling of Peripheral Whole Blood

(2009) Ze Tian et al.   PLoS One

Enhanced Monocyte Response and Decreased Central Memory T Cells in Children with Invasive Staphylococcus aureus Infections

(2009) Monica I. Ardura et al.   PLoS One

IFN  kinoid vaccine-induced neutralizing antibodies prevent clinical manifestations in a lupus flare murine model

(2009) D. Zagury et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of IRAK1 as a risk gene with critical role in the pathogenesis of systemic lupus erythematosus

(2009) C. O. Jacob et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Endosomal TLR signaling is required for anti-nucleic acid and rheumatoid factor autoantibodies in lupus

(2009) D. H. Kono et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Absence of autophagy results in reactive oxygen species-dependent amplification of RLR signaling

(2009) Michal Caspi Tal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Immunopathogenesis of Rheumatoid Arthritis

(2008) John B. Imboden   Annual Review of Pathology-Mechanisms of Disease

S100A12 is a novel molecular marker differentiating systemic-onset juvenile idiopathic arthritis from other causes of fever of unknown origin

(2008) Helmut Wittkowski et al.   ARTHRITIS AND RHEUMATISM

Association of the IRF5 risk haplotype with high serum interferon-α activity in systemic lupus erythematosus patients

(2008) Timothy B. Niewold et al.   ARTHRITIS AND RHEUMATISM

Trex1 Prevents Cell-Intrinsic Initiation of Autoimmunity

(2008) Daniel B. Stetson et al.   CELL

Reproducible and reliable microarray results through quality control: good laboratory proficiency and appropriate data analysis practices are essential

(2008) Leming Shi et al.   CURRENT OPINION IN BIOTECHNOLOGY

Belimumab, an anti-BLyS human monoclonal antibody for potential treatment of inflammatory autoimmune diseases

(2008) Changhai Ding   EXPERT OPINION ON BIOLOGICAL THERAPY

Additive effects of the major risk alleles of IRF5 and STAT4 in primary Sjögren's syndrome

(2008) G Nordmark et al.   GENES AND IMMUNITY

Variant form of STAT4 is associated with primary Sjögren's syndrome

(2008) B D Korman et al.   GENES AND IMMUNITY

A Modular Analysis Framework for Blood Genomics Studies: Application to Systemic Lupus Erythematosus

(2008) Damien Chaussabel et al.   IMMUNITY

A Prescription for Human Immunology

(2008) Mark M. Davis   IMMUNITY

How the study of children with rheumatic diseases identified interferon-α and interleukin-1 as novel therapeutic targets

(2008) Virginia Pascual et al.   IMMUNOLOGICAL REVIEWS

Systems biology of innate immunity

(2008) Daniel E. Zak et al.   IMMUNOLOGICAL REVIEWS

The TREX1 Double-stranded DNA Degradation Activity Is Defective in Dominant Mutations Associated with Autoimmune Disease

(2008) Duane A. Lehtinen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Juvenile dermatomyositis and other idiopathic inflammatory myopathies of childhood

(2008) Brian M Feldman et al.   LANCET

Rapid cloning of high-affinity human monoclonal antibodies against influenza virus

(2008) Jens Wrammert et al.   NATURE

Direct multiplexed measurement of gene expression with color-coded probe pairs

(2008) Gary K Geiss et al.   NATURE BIOTECHNOLOGY

Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci

(2008) John B Harley et al.   NATURE GENETICS

RNA-Seq: a revolutionary tool for transcriptomics

(2008) Zhong Wang et al.   NATURE REVIEWS GENETICS

Molecular Subsets in the Gene Expression Signatures of Scleroderma Skin

(2008) Ausra Milano et al.   PLoS One

A Global View of Gene Activity and Alternative Splicing by Deep Sequencing of the Human Transcriptome

(2008) M. Sultan et al.   SCIENCE

Geometric Interpretation of Gene Coexpression Network Analysis

(2008) Steve Horvath et al.   PLoS Computational Biology

Interference of globin genes with biomarker discovery for allograft rejection in peripheral blood samples

(2007) Li Li et al.   PHYSIOLOGICAL GENOMICS