DNA hypermethylation of sFRP5 contributes to indoxyl sulfate-induced renal fibrosis

Klotho Protects Against Indoxyl Sulphate-Induced Myocardial Hypertrophy

(2015) K. Yang et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Protein-bound Uremic Toxins, Inflammation and Oxidative Stress: A Cross-sectional Study in Stage 3–4 Chronic Kidney Disease

(2014) Megan Rossi et al.   ARCHIVES OF MEDICAL RESEARCH

Secreted Frizzled-related Protein 1 (Sfrp1) Regulates the Progression of Renal Fibrosis in a Mouse Model of Obstructive Nephropathy

(2014) Makoto Matsuyama et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Picrosirius Red Staining

(2014) Raed Lattouf et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Klotho suppresses renal tubulo-interstitial fibrosis by controlling basic fibroblast growth factor-2 signalling

(2014) Xu Guan et al.   JOURNAL OF PATHOLOGY

Multiple Genes of the Renin-Angiotensin System Are Novel Targets of Wnt/ -Catenin Signaling

(2014) L. Zhou et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

GEC-derived SFRP5 Inhibits Wnt5a-Induced Macrophage Chemotaxis and Activation

(2014) Chenghai Zhao et al.   PLoS One

A Pharmaco-Metabonomic Study on Chronic Kidney Disease and Therapeutic Effect of Ergone by UPLC-QTOF/HDMS

(2014) Ying-Yong Zhao et al.   PLoS One

Downregulation of sFRP-2 by epigenetic silencing activates the β-catenin/Wnt signaling pathway in esophageal basaloid squamous cell carcinoma

(2014) Tsuyoshi Saito et al.   VIRCHOWS ARCHIV

Epigenetic silencing ofSFRP1andSFRP5by hepatitis B virus X protein enhances hepatoma cell tumorigenicity through Wnt signaling pathway

(2013) Qing Xie et al.   INTERNATIONAL JOURNAL OF CANCER

Loss of Klotho Contributes to Kidney Injury by Derepression of Wnt/ -Catenin Signaling

(2013) L. Zhou et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

p -Cresyl sulfate causes renal tubular cell damage by inducing oxidative stress by activation of NADPH oxidase

(2013) Hiroshi Watanabe et al.   KIDNEY INTERNATIONAL

The role of protein-bound uremic toxins on peripheral artery disease and vascular access failure in patients on hemodialysis

(2012) Cheng-Jui Lin et al.   ATHEROSCLEROSIS

Gene expression and epigenetic discovery screen reveal methylation of SFRP2 in prostate cancer

(2012) Antoinette S. Perry et al.   INTERNATIONAL JOURNAL OF CANCER

Suppression of Klotho expression by protein-bound uremic toxins is associated with increased DNA methyltransferase expression and DNA hypermethylation

(2012) Chiao-Yin Sun et al.   KIDNEY INTERNATIONAL

p-Cresol sulfate and indoxyl sulfate induce similar cellular inflammatory gene expressions in cultured proximal renal tubular cells

(2012) C.-Y. Sun et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Epigenetic silencing of sFRP1 activates the canonical Wnt pathway and contributes to increased cell growth and proliferation in hepatocellular carcinoma

(2012) Pushpinder Kaur et al.   TUMOR BIOLOGY

NF-κB plays an important role in indoxyl sulfate-induced cellular senescence, fibrotic gene expression, and inhibition of proliferation in proximal tubular cells

(2011) Hidehisa Shimizu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Wnt-signaling pathways in progressive renal fibrosis

(2011) Peter J Nelson et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Matrix Metalloproteinase-7 as a Surrogate Marker Predicts Renal Wnt/ -Catenin Activity in CKD

(2011) W. He et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Serum free p-cresyl sulfate levels predict cardiovascular and all-cause mortality in elderly hemodialysis patients--a prospective cohort study

(2011) I.-W. Wu et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Does indoxyl sulfate, a uraemic toxin, have direct effects on cardiac fibroblasts and myocytes?

(2010) S. Lekawanvijit et al.   EUROPEAN HEART JOURNAL

Sfrp5 Is an Anti-Inflammatory Adipokine That Modulates Metabolic Dysfunction in Obesity

(2010) N. Ouchi et al.   SCIENCE

Serum Indoxyl Sulfate Is Associated with Vascular Disease and Mortality in Chronic Kidney Disease Patients

(2009) F. C. Barreto et al.   Clinical Journal of the American Society of Nephrology

Emerging Biomarkers for Evaluating Cardiovascular Risk in the Chronic Kidney Disease Patient: How Do New Pieces Fit into the Uremic Puzzle?

(2008) P. Stenvinkel et al.   Clinical Journal of the American Society of Nephrology

Deciphering the function of canonical Wnt signals in development and disease: conditional loss- and gain-of-function mutations of  -catenin in mice

(2008) T. Grigoryan et al.   GENES & DEVELOPMENT