Sequential combination of docetaxel with a SHP-1 agonist enhanced suppression of p-STAT3 signaling and apoptosis in triple negative breast cancer cells

Tumor microenvironment and cancer therapy resistance

(2016) Yu Sun   CANCER LETTERS

A combination of sorafenib and SC-43 is a synergistic SHP-1 agonist duo to advance hepatocellular carcinoma therapy

(2016) Tzu-I Chao et al.   CANCER LETTERS

Implication of protein tyrosine phosphatase SHP-1 in cancer-related signaling pathways

(2016) Yadhu Sharma et al.   Future Oncology

New treatment strategies for patients with triple-negative breast cancer

(2015) Cornelia Liedtke et al.   CURRENT OPINION IN OBSTETRICS & GYNECOLOGY

Investigational therapies targeting signal transducer and activator of transcription 3 for the treatment of cancer

(2015) Matteo Santoni et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Constitutive activation of STAT3 in breast cancer cells: A review

(2015) Kasturi Banerjee et al.   INTERNATIONAL JOURNAL OF CANCER

Targeted Therapies for Triple-Negative Breast Cancer: Combating a Stubborn Disease

(2015) Murugan Kalimutho et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

The role of taxanes in triple-negative breast cancer: literature review

(2015) Giorgio Mustacchi et al.   Drug Design Development and Therapy

Pharmacological Targeting SHP-1-STAT3 Signaling Is a Promising Therapeutic Approach for the Treatment of Colorectal Cancer

(2015) Li-Ching Fan et al.   NEOPLASIA

The value of platinum agents as neoadjuvant chemotherapy in triple-negative breast cancers: a systematic review and meta-analysis

(2014) Fausto Petrelli et al.   BREAST CANCER RESEARCH AND TREATMENT

SOCS3-mediated regulation of inflammatory cytokines in PTEN and p53 inactivated triple negative breast cancer model

(2014) G Kim et al.   ONCOGENE

Bioinformatic analysis reveals a pattern of STAT3-associated gene expression specific to basal-like breast cancers in human tumors

(2014) R. W. Tell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Growth of Triple-Negative Breast Cancer Cells Relies upon Coordinate Autocrine Expression of the Proinflammatory Cytokines IL-6 and IL-8

(2013) Z. C. Hartman et al.   CANCER RESEARCH

Differential Response to Neoadjuvant Chemotherapy Among 7 Triple-Negative Breast Cancer Molecular Subtypes

(2013) H. Masuda et al.   CLINICAL CANCER RESEARCH

Trichosanthes kirilowiiEthanol Extract and Cucurbitacin D Inhibit Cell Growth and Induce Apoptosis through Inhibition of STAT3 Activity in Breast Cancer Cells

(2013) Soon Re Kim et al.   Evidence-based Complementary and Alternative Medicine

Discovery of novel src homology region 2 domain-containing phosphatase 1 agonists from sorafenib for the treatment of hepatocellular carcinoma

(2013) Wei-Tien Tai et al.   HEPATOLOGY

Distinct roles of STAT3 and STAT5 in the pathogenesis and targeted therapy of breast cancer

(2013) Sarah R. Walker et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

SHP-1 in Cell-Cycle Regulation

(2012) Pilar Lopez-Ruiz et al.   Anti-Cancer Agents in Medicinal Chemistry

Sequential Application of Anticancer Drugs Enhances Cell Death by Rewiring Apoptotic Signaling Networks

(2012) Michael J. Lee et al.   CELL

Effects of the combination of RAD001 and docetaxel on breast cancer stem cells

(2012) Xiaobei Zhang et al.   EUROPEAN JOURNAL OF CANCER

Synthesis and biological activity of obatoclax derivatives as novel and potent SHP-1 agonists

(2012) Jung-Chen Su et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

TCPTP Regulates SFK and STAT3 Signaling and Is Lost in Triple-Negative Breast Cancers

(2012) Benjamin J. Shields et al.   MOLECULAR AND CELLULAR BIOLOGY

RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome

(2011) Bo Li et al.   BMC BIOINFORMATICS

Oral administration of penta-O-galloyl- -D-glucose suppresses triple-negative breast cancer xenograft growth and metastasis in strong association with JAK1-STAT3 inhibition

(2011) H.-J. Lee et al.   CARCINOGENESIS

The JAK2/STAT3 signaling pathway is required for growth of CD44+CD24– stem cell–like breast cancer cells in human tumors

(2011) Lauren L.C. Marotta et al.   JOURNAL OF CLINICAL INVESTIGATION

Overexpression and Small Molecule-Triggered Downregulation of CIP2A in Lung Cancer

(2011) Liang Ma et al.   PLoS One

Drug Combination Studies and Their Synergy Quantification Using the Chou-Talalay Method

(2010) T.-C. Chou   CANCER RESEARCH

Phase 3 study comparing the use of docetaxel on an every-3-week versus weekly schedule in the treatment of metastatic breast cancer

(2008) Edgardo Rivera et al.   CANCER

Preoperative Chemotherapy: Updates of National Surgical Adjuvant Breast and Bowel Project Protocols B-18 and B-27

(2008) Priya Rastogi et al.   JOURNAL OF CLINICAL ONCOLOGY

Response to Neoadjuvant Therapy and Long-Term Survival in Patients With Triple-Negative Breast Cancer

(2008) Cornelia Liedtke et al.   JOURNAL OF CLINICAL ONCOLOGY