TCPTP Regulates SFK and STAT3 Signaling and Is Lost in Triple-Negative Breast Cancers

IL6-Mediated Suppression of miR-200c Directs Constitutive Activation of Inflammatory Signaling Circuit Driving Transformation and Tumorigenesis

(2012) Matjaz Rokavec et al.   MOLECULAR CELL

Tyrosine phosphatase SHP2 promotes breast cancer progression and maintains tumor-initiating cells via activation of key transcription factors and a positive feedback signaling loop

(2012) Nicola Aceto et al.   NATURE MEDICINE

Strain-Dependent Differences in Bone Development, Myeloid Hyperplasia, Morbidity and Mortality in Ptpn2-Deficient Mice

(2012) Florian Wiede et al.   PLoS One

PTPN2 negatively regulates oncogenic JAK1 in T-cell acute lymphoblastic leukemia

(2011) M. Kleppe et al.   BLOOD

Activation of Multiple Proto-oncogenic Tyrosine Kinases in Breast Cancer via Loss of the PTPN12 Phosphatase

(2011) Tingting Sun et al.   CELL

Elevated Hypothalamic TCPTP in Obesity Contributes to Cellular Leptin Resistance

(2011) Kim Loh et al.   Cell Metabolism

Triple-negative breast cancers: an updated review on treatment options

(2011) K. B. Reddy   Current Oncology

Tyrosine Phosphorylation Profiling Reveals the Signaling Network Characteristics of Basal Breast Cancer Cells

(2010) F. Hochgrafe et al.   CANCER RESEARCH

Cell cycle-dependent regulation of SFK, JAK1 and STAT3 signaling by the protein tyrosine phosphatase TCPTP

(2010) Ben J. Shields et al.   CELL CYCLE

T-Cell Protein Tyrosine Phosphatase Attenuates STAT3 and Insulin Signaling in the Liver to Regulate Gluconeogenesis

(2010) Atsushi Fukushima et al.   DIABETES

Epigenetic control of the basal-like gene expression profile via Interleukin-6 in breast cancer cells

(2010) Laura D'Anello et al.   Molecular Cancer

STAT3 Activation of miR-21 and miR-181b-1 via PTEN and CYLD Are Part of the Epigenetic Switch Linking Inflammation to Cancer

(2010) Dimitrios Iliopoulos et al.   MOLECULAR CELL

Deletion of the protein tyrosine phosphatase gene PTPN2 in T-cell acute lymphoblastic leukemia

(2010) Maria Kleppe et al.   NATURE GENETICS

DNA Replication Stalling Attenuates Tyrosine Kinase Signaling to Suppress S Phase Progression

(2008) Ben J. Shields et al.   CANCER CELL

How different are luminal A and basal breast cancers?

(2008) François Bertucci et al.   INTERNATIONAL JOURNAL OF CANCER