Integrative studies implicate matrix metalloproteinase-12 as a culprit gene for large-artery atherosclerotic stroke

Phenotypic Modulation of Smooth Muscle Cells in Atherosclerosis Is Associated With Downregulation ofLMOD1, SYNPO2, PDLIM7, PLN, andSYNMHighlights

(2016) Ljubica Perisic Matic et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Elevated Plasma Levels of MMP-12 Are Associated With Atherosclerotic Burden and Symptomatic Cardiovascular Disease in Subjects With Type 2 DiabetesSignificance

(2015) Isabel Goncalves et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

How does lipid lowering prevent coronary events? New insights from human imaging trials

(2015) P. Libby   EUROPEAN HEART JOURNAL

Potential clinical implications of recent matrix metalloproteinase inhibitor design strategies

(2015) Sabrina Amar et al.   Expert Review of Proteomics

Gene expression signatures, pathways and networks in carotid atherosclerosis

(2015) L. Perisic et al.   JOURNAL OF INTERNAL MEDICINE

Second-generation PLINK: rising to the challenge of larger and richer datasets

(2015) Christopher C Chang et al.   GigaScience

SNiPA: an interactive, genetic variant-centered annotation browser

(2014) Matthias Arnold et al.   BIOINFORMATICS

Impact of Matrix Metalloproteinases on Atherosclerosis

(2014) Juntang Lin et al.   CURRENT DRUG TARGETS

Proteinases and plaque rupture

(2014) Andrew C. Newby   CURRENT OPINION IN LIPIDOLOGY

Epidemiological studies of CHD and the evolution of preventive cardiology

(2014) Nathan D. Wong   Nature Reviews Cardiology

Homogenous 96-Plex PEA Immunoassay Exhibiting High Sensitivity, Specificity, and Excellent Scalability

(2014) Erika Assarsson et al.   PLoS One

A Novel MMP12 Locus Is Associated with Large Artery Atherosclerotic Stroke Using a Genome-Wide Age-at-Onset Informed Approach

(2014) Matthew Traylor et al.   PLoS Genetics

Risk loci for chronic obstructive pulmonary disease: a genome-wide association study and meta-analysis

(2014) Michael H Cho et al.   Lancet Respiratory Medicine

Profiling of Atherosclerotic Lesions by Gene and Tissue Microarrays Reveals PCSK6 as a Novel Protease in Unstable Carotid Atherosclerosis

(2013) Ljubica Perisic et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Progression of Carotid Intima-Media Thickness as Predictor of Vascular Events

(2013) Damiano Baldassarre et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Carotid Atherosclerotic Plaque Matrix Metalloproteinase‐12–Positive Macrophage Subpopulation Predicts Adverse Outcome After Endarterectomy

(2013) Vincent P. W. Scholtes et al.   Journal of the American Heart Association

Identification of the BCAR1-CFDP1-TMEM170A Locus as a Determinant of Carotid Intima-Media Thickness and Coronary Artery Disease Risk

(2012) Karl Gertow et al.   Circulation-Cardiovascular Genetics

Measurements of Carotid Intima-Media Thickness and of Interadventitia Common Carotid Diameter Improve Prediction of Cardiovascular Events

(2012) Damiano Baldassarre et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

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(2012) Lasse Folkersen et al.   MOLECULAR MEDICINE

A Selective Matrix Metalloproteinase-12 Inhibitor Retards Atherosclerotic Plaque Development in Apolipoprotein E–Knockout Mice

(2011) Jason L. Johnson et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Altered expression of inflammation-related genes in human carotid atherosclerotic plaques

(2011) Maria Donata Di Taranto et al.   ATHEROSCLEROSIS

Correlations Between Clinical Variables and Gene-expression Profiles in Carotid Plaque Instability

(2011) A. Razuvaev et al.   EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY

Progress and challenges in translating the biology of atherosclerosis

(2011) Peter Libby et al.   NATURE

Carotid Plaque Vulnerability

(2011) Iwona Cicha et al.   STROKE

Promise and pitfalls of the Immunochip

(2011) Adrian Cortes et al.   ARTHRITIS RESEARCH & THERAPY

Relations of Biomarkers of Extracellular Matrix Remodeling to Incident Cardiovascular Events and Mortality

(2010) Raghava S. Velagaleti et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Advanced human carotid plaque progression correlates positively with flow shear stress using follow-up scan data: An in vivo MRI multi-patient 3D FSI study

(2010) Chun Yang et al.   JOURNAL OF BIOMECHANICS

10-year stroke prevention after successful carotid endarterectomy for asymptomatic stenosis (ACST-1): a multicentre randomised trial

(2010) Alison Halliday et al.   LANCET

Prospective study of matrix metalloproteinase-9 and risk of myocardial infarction and stroke in older men and women

(2009) Barbara J. Jefferis et al.   ATHEROSCLEROSIS

Differences in Lesion Severity and Cellular Composition between in vivo Assessed Upstream and Downstream Sides of Human Symptomatic Carotid Atherosclerotic Plaques

(2009) Björn Fagerberg et al.   JOURNAL OF VASCULAR RESEARCH

MMP12,Lung Function, and COPD in High-Risk Populations

(2009) Gary M. Hunninghake et al.   NEW ENGLAND JOURNAL OF MEDICINE