Disrupting galectin-1 interactions with N-glycans suppresses hypoxia-driven angiogenesis and tumorigenesis in Kaposi’s sarcoma

Galectin-1 inhibits the viability, proliferation, and Th1 cytokine production of nonmalignant T cells in patients with leukemic cutaneous T-cell lymphoma

(2012) F. Cedeno-Laurent et al.   BLOOD

Inhibiting galectin-1 reduces murine lung metastasis with increased CD4+ and CD8+ T cells and reduced cancer cell adherence

(2012) Koichi Ito et al.   CLINICAL & EXPERIMENTAL METASTASIS

Regulatory Circuits Mediated by Lectin-Glycan Interactions in Autoimmunity and Cancer

(2012) Gabriel A. Rabinovich et al.   IMMUNITY

Developmental and Pathological Angiogenesis

(2011) Alicia S. Chung et al.   Annual Review of Cell and Developmental Biology

Viral induction and targeted inhibition of galectin-1 in EBV+ posttransplant lymphoproliferative disorders

(2011) J. Ouyang et al.   BLOOD

PI3Kγ Mediates Kaposi's Sarcoma-Associated Herpesvirus vGPCR-Induced Sarcomagenesis

(2011) Daniel Martin et al.   CANCER CELL

Tumor Galectin-1 Mediates Tumor Growth and Metastasis through Regulation of T-Cell Apoptosis

(2011) A. Banh et al.   CANCER RESEARCH

A novel strategy for evasion of NK cell immunity by tumours expressing core2 O-glycans

(2011) Shigeru Tsuboi et al.   EMBO JOURNAL

High expression of Galectin-1 in pancreatic stellate cells plays a role in the development and maintenance of an immunosuppressive microenvironment in pancreatic cancer

(2011) Dong Tang et al.   INTERNATIONAL JOURNAL OF CANCER

Synergistic Induction of Galectin-1 by CCAAT/Enhancer Binding Protein α and Hypoxia-inducible Factor 1α and Its Role in Differentiation of Acute Myeloid Leukemic Cells

(2011) Xu-Yun Zhao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Galectin-3 Protein Modulates Cell Surface Expression and Activation of Vascular Endothelial Growth Factor Receptor 2 in Human Endothelial Cells

(2011) Anna I. Markowska et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Anti-angiogenic Peptide Anginex Greatly Enhances Galectin-1 Binding Affinity for Glycoproteins

(2011) Emma Salomonsson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Generation of a doxycycline-inducible KSHV producer cell line of endothelial origin: Maintenance of tight latency with efficient reactivation upon induction

(2011) Jinjong Myoung et al.   JOURNAL OF VIROLOGICAL METHODS

Host-Soluble Galectin-1 Promotes HIV-1 Replication through a Direct Interaction with Glycans of Viral gp120 and Host CD4

(2011) C. St-Pierre et al.   JOURNAL OF VIROLOGY

Nuclear factor (NF)-κB controls expression of the immunoregulatory glycan-binding protein galectin-1

(2011) Marta A. Toscano et al.   MOLECULAR IMMUNOLOGY

Reactive Oxygen Species Hydrogen Peroxide Mediates Kaposi's Sarcoma-Associated Herpesvirus Reactivation from Latency

(2011) Fengchun Ye et al.   PLoS Pathogens

The Increasing Burden of HIV-Associated Malignancies in Resource-Limited Regions

(2010) Corey Casper   Annual Review of Medicine

Tumor Cells Secrete Galectin-1 to Enhance Endothelial Cell Activity

(2010) V. L. Thijssen et al.   CANCER RESEARCH

Hypoxia inducible factor-1 mediates expression of galectin-1: the potential role in migration/invasion of colorectal cancer cells

(2010) Xu-Yun Zhao et al.   CARCINOGENESIS

Modulation of endothelial cell migration and angiogenesis: a novel function for the “tandem-repeat” lectin galectin-8

(2010) Víctor M. Cárdenas Delgado et al.   FASEB JOURNAL

KSHV and the pathogenesis of Kaposi sarcoma: listening to human biology and medicine

(2010) Don Ganem   JOURNAL OF CLINICAL INVESTIGATION

Galectin-3 is an important mediator of VEGF- and bFGF-mediated angiogenic response

(2010) Anna I. Markowska et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Lung Cancer-Derived Galectin-1 Mediates Dendritic Cell Anergy through Inhibitor of DNA Binding 3/IL-10 Signaling Pathway

(2010) P.-L. Kuo et al.   JOURNAL OF IMMUNOLOGY

An Intact Canonical NF- B Pathway Is Required for Inflammatory Gene Expression in Response to Hypoxia

(2010) S. F. Fitzpatrick et al.   JOURNAL OF IMMUNOLOGY

Viral G protein-coupled receptor up-regulates Angiopoietin-like 4 promoting angiogenesis and vascular permeability in Kaposi's sarcoma

(2010) T. Ma et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tumor Vasculature Is Regulated by PHD2-Mediated Angiogenesis and Bone Marrow-Derived Cell Recruitment

(2009) Denise A. Chan et al.   CANCER CELL

Regulation of Angiogenesis by Oxygen and Metabolism

(2009) Peter Fraisl et al.   DEVELOPMENTAL CELL

KSHV downregulation of galectin-3 in Kaposi's sarcoma

(2009) D. J. Alcendor et al.   GLYCOBIOLOGY

Tolerogenic signals delivered by dendritic cells to T cells through a galectin-1-driven immunoregulatory circuit involving interleukin 27 and interleukin 10

(2009) Juan M Ilarregui et al.   NATURE IMMUNOLOGY

Antitumorigenesis of antioxidants in a transgenic Rac1 model of Kaposi's sarcoma

(2009) Q. Ma et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Critical Loss of the Balance between Th17 and T Regulatory Cell Populations in Pathogenic SIV Infection

(2009) David Favre et al.   PLoS Pathogens

Dual Inhibition of PI3K  and mTOR as an Alternative Treatment for Kaposi's Sarcoma

(2008) R. Chaisuparat et al.   CANCER RESEARCH

NF-κB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1α

(2008) Jordi Rius et al.   NATURE

Galectin-1, a novel ligand of neuropilin-1, activates VEGFR-2 signaling and modulates the migration of vascular endothelial cells

(2008) S H Hsieh et al.   ONCOGENE

Inhibitory control of endothelial galectin-1 on in vitro and in vivo lymphocyte trafficking

(2007) Lucy V. Norling et al.   FASEB JOURNAL