Filamin A Regulates Neutrophil Adhesion, Production of Reactive Oxygen Species, and Neutrophil Extracellular Trap Release

Optimal T Cell Activation and B Cell Antibody Responses In Vivo Require the Interaction between Leukocyte Function–Associated Antigen-1 and Kindlin-3

(2015) Vicky Louise Morrison et al.   JOURNAL OF IMMUNOLOGY

Functional Beta2-Integrins Restrict Skin Inflammation In Vivo

(2015) Terhi S. Savinko et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Structural mechanism of integrin inactivation by filamin

(2015) Jianmin Liu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structural mechanism of integrin inactivation by filamin

(2015) Jianmin Liu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Mice Lacking beta2-Integrin Function Remain Glucose Tolerant in Spite of Insulin Resistance, Neutrophil Infiltration and Inflammation

(2015) Paul J. Meakin et al.   PLoS One

Involvement of IKAP in Peripheral Target Innervation and in Specific JNK and NGF Signaling in Developing PNS Neurons

(2014) Anastasia Abashidze et al.   PLoS One

Loss of beta2-integrin-mediated cytoskeletal linkage reprogrammes dendritic cells to a mature migratory phenotype

(2014) Vicky Louise Morrison et al.   Nature Communications

A Myeloperoxidase-Containing Complex Regulates Neutrophil Elastase Release and Actin Dynamics during NETosis

(2014) Kathleen D. Metzler et al.   Cell Reports

NADPH Oxidase Complex-Derived Reactive Oxygen Species, the Actin Cytoskeleton, and Rho GTPases in Cell Migration

(2013) Alanna Stanley et al.   ANTIOXIDANTS & REDOX SIGNALING

The  2 integrin-kindlin-3 interaction is essential for T-cell homing but dispensable for T-cell activation in vivo

(2013) V. L. Morrison et al.   BLOOD

Filamin-A Regulates Neutrophil Uropod Retraction through RhoA during Chemotaxis

(2013) Chunxiang Sun et al.   PLoS One

Filamins in Mechanosensing and Signaling

(2012) Ziba Razinia et al.   Annual Review of Biophysics

Macrophage Mesenchymal Migration Requires Podosome Stabilization by Filamin A

(2012) Romain Guiet et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Neutrophil extracellular traps: Is immunity the second function of chromatin?

(2012) Volker Brinkmann et al.   JOURNAL OF CELL BIOLOGY

Migrational Guidance of Neutrophils Is Mechanotransduced via High-Affinity LFA-1 and Calcium Flux

(2011) N. Dixit et al.   JOURNAL OF IMMUNOLOGY

Filamin depletion blocks endoplasmic spreading and destabilizes force-bearing adhesions

(2011) Christopher D. Lynch et al.   MOLECULAR BIOLOGY OF THE CELL

Migfilin and Filamin as Regulators of Integrin Activation in Endothelial Cells and Neutrophils

(2011) Mitali Das et al.   PLoS One

Filamin A mediates interactions between cytoskeletal proteins that control cell adhesion

(2010) Hugh Kim et al.   FEBS LETTERS

A novel interaction between FlnA and Syk regulates platelet ITAM-mediated receptor signaling and function

(2010) Hervé Falet et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Regulation of integrin activity and signalling

(2009) Carl G. Gahmberg et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Neutrophil-specific deletion of Syk kinase results in reduced host defense to bacterial infection

(2009) J. A. Van Ziffle et al.   BLOOD

Genetic etiologies of leukocyte adhesion defects

(2009) Amos Etzioni   CURRENT OPINION IN IMMUNOLOGY

Regulation of Extracellular Chromatin Release from Neutrophils

(2009) Indira Neeli et al.   Journal of Innate Immunity

Kindlin-3 is required for β2 integrin–mediated leukocyte adhesion to endothelial cells

(2009) Markus Moser et al.   NATURE MEDICINE

Filamins Regulate Cell Spreading and Initiation of Cell Migration

(2009) Massimiliano Baldassarre et al.   PLoS One

Neutrophil Extracellular Traps Contain Calprotectin, a Cytosolic Protein Complex Involved in Host Defense against Candida albicans

(2009) Constantin F. Urban et al.   PLoS Pathogens

 2 integrin phosphorylation on Thr758 acts as a molecular switch to regulate 14-3-3 and filamin binding

(2008) H. Takala et al.   BLOOD

CD18-dependent activation of the neutrophil NADPH oxidase during phagocytosis of Escherichia coli or Staphylococcus aureus is regulated by class III but not class I or II PI3Ks

(2008) K. E. Anderson et al.   BLOOD

Migfilin, a Molecular Switch in Regulation of Integrin Activation

(2008) Sujay Subbayya Ithychanda et al.   JOURNAL OF BIOLOGICAL CHEMISTRY