Migfilin, a Molecular Switch in Regulation of Integrin Activation

 2 integrin phosphorylation on Thr758 acts as a molecular switch to regulate 14-3-3 and filamin binding

(2008) H. Takala et al.   BLOOD

Kindlin-2 controls bidirectional signaling of integrins

(2008) E. Montanez et al.   GENES & DEVELOPMENT

Structural Basis of the Migfilin-Filamin Interaction and Competition with Integrin β Tails

(2008) Yatish Lad et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mechanisms and consequences of agonist-induced talin recruitment to platelet integrin αIIbβ3

(2008) Naohide Watanabe et al.   JOURNAL OF CELL BIOLOGY

Kindlin-2 (Mig-2): a co-activator of β3integrins

(2008) Yan-Qing Ma et al.   JOURNAL OF CELL BIOLOGY

Cell adaptive response to extracellular matrix density is controlled by ICAP-1–dependent β1-integrin affinity

(2008) Angélique Millon-Frémillon et al.   JOURNAL OF CELL BIOLOGY

Kindlin-3 is essential for integrin activation and platelet aggregation

(2008) Markus Moser et al.   NATURE MEDICINE