Palmitate Conditions Macrophages for Enhanced Responses toward Inflammatory Stimuli via JNK Activation

MAFB Determines Human Macrophage Anti-Inflammatory Polarization: Relevance for the Pathogenic Mechanisms Operating in Multicentric Carpotarsal Osteolysis

(2017) Víctor D. Cuevas et al.   JOURNAL OF IMMUNOLOGY

Tripping on TRIB3 at the junction of health, metabolic dysfunction and cancer

(2016) Debasis Mondal et al.   BIOCHIMIE

Obesity and Cancer Mechanisms: Cancer Metabolism

(2016) Benjamin D. Hopkins et al.   JOURNAL OF CLINICAL ONCOLOGY

Atypical Activin A and IL-10 Production Impairs Human CD16+Monocyte Differentiation into Anti-Inflammatory Macrophages

(2016) Érika González-Domínguez et al.   JOURNAL OF IMMUNOLOGY

Initial hyperinsulinemia and subsequent β-cell dysfunction is associated with elevated palmitate levels

(2016) Johan Staaf et al.   PEDIATRIC RESEARCH

Trained immunity: A program of innate immune memory in health and disease

(2016) M. G. Netea et al.   SCIENCE

Reshaping of Human Macrophage Polarization through Modulation of Glucose Catabolic Pathways

(2015) Elena Izquierdo et al.   JOURNAL OF IMMUNOLOGY

Effects of palmitate on genome-wide mRNA expression and DNA methylation patterns in human pancreatic islets

(2014) Elin Hall et al.   BMC Medicine

Metabolic Dysfunction Drives a Mechanistically Distinct Proinflammatory Phenotype in Adipose Tissue Macrophages

(2014) Mario Kratz et al.   Cell Metabolism

Palmitate Induces TRB3 Expression and Promotes Apoptosis in Human Liver Cells

(2014) Weihui Yan et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Transcriptome-Based Network Analysis Reveals a Spectrum Model of Human Macrophage Activation

(2014) Jia Xue et al.   IMMUNITY

Bacterial DNA Translocation Holds Increased Insulin Resistance and Systemic Inflammatory Levels in Morbid Obese Patients

(2014) Sergio Ortiz et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

CCL2 Shapes Macrophage Polarization by GM-CSF and M-CSF: Identification of CCL2/CCR2-Dependent Gene Expression Profile

(2014) E. Sierra-Filardi et al.   JOURNAL OF IMMUNOLOGY

Macrophages from the synovium of active rheumatoid arthritis exhibit an activin A-dependent pro-inflammatory profile

(2014) Blanca Soler Palacios et al.   JOURNAL OF PATHOLOGY

mTOR- and HIF-1 -mediated aerobic glycolysis as metabolic basis for trained immunity

(2014) S.-C. Cheng et al.   SCIENCE

Epigenetic programming of monocyte-to-macrophage differentiation and trained innate immunity

(2014) S. Saeed et al.   SCIENCE

GSK3-mediated MAF phosphorylation in multiple myeloma as a potential therapeutic target

(2014) N I Herath et al.   Blood Cancer Journal

Free fatty acid determination in plasma by GC-MS after conversion to Weinreb amides

(2013) Sarojini J. K. A. Ubhayasekera et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Epidemiology and Molecular Mechanisms Tying Obesity, Diabetes, and the Metabolic Syndrome With Cancer

(2013) E. J. Gallagher et al.   DIABETES CARE

The inflammation highway: metabolism accelerates inflammatory traffic in obesity

(2012) Amy R. Johnson et al.   IMMUNOLOGICAL REVIEWS

The Prolyl Hydroxylase PHD3 Identifies Proinflammatory Macrophages and Its Expression Is Regulated by Activin A

(2012) M. M. Escribese et al.   JOURNAL OF IMMUNOLOGY

Defining GM-CSF- and Macrophage-CSF-Dependent Macrophage Responses by In Vitro Models

(2012) D. C. Lacey et al.   JOURNAL OF IMMUNOLOGY

Saturated fatty acids activate TLR-mediated proinflammatory signaling pathways

(2012) Shurong Huang et al.   JOURNAL OF LIPID RESEARCH

Fetuin-A acts as an endogenous ligand of TLR4 to promote lipid-induced insulin resistance

(2012) Durba Pal et al.   NATURE MEDICINE

JNK Expression by Macrophages Promotes Obesity-Induced Insulin Resistance and Inflammation

(2012) M. S. Han et al.   SCIENCE

Alternative Macrophage Activation and Metabolism

(2011) Justin I. Odegaard et al.   Annual Review of Pathology-Mechanisms of Disease

Activin A skews macrophage polarization by promoting a proinflammatory phenotype and inhibiting the acquisition of anti-inflammatory macrophage markers

(2011) E. Sierra-Filardi et al.   BLOOD

Inflammatory links between obesity and metabolic disease

(2011) Carey N. Lumeng et al.   JOURNAL OF CLINICAL INVESTIGATION

Loss of function mutation in toll-like receptor-4 does not offer protection against obesity and insulin resistance induced by a diet high in trans fat in mice

(2011) Matam Vijay-Kumar et al.   Journal of Inflammation-London

Evaluation of foam cell formation in cultured macrophages: an improved method with Oil Red O staining and DiI-oxLDL uptake

(2010) Suowen Xu et al.   CYTOTECHNOLOGY

Myeloid Differentiation Factor 88 (MyD88)-Deficiency Increases Risk of Diabetes in Mice

(2010) Toru Hosoi et al.   PLoS One

MafB protein stability is regulated by the JNK and ubiquitin–proteasome pathways

(2009) Hiroshi Tanahashi et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Saturated Fatty Acids Do Not Directly Stimulate Toll-Like Receptor Signaling

(2009) Clett Erridge et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Aryl hydrocarbon receptor in combination with Stat1 regulates LPS-induced inflammatory responses

(2009) Akihiro Kimura et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A CREB-C/EBP  cascade induces M2 macrophage-specific gene expression and promotes muscle injury repair

(2009) D. Ruffell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ablation of CD11c-Positive Cells Normalizes Insulin Sensitivity in Obese Insulin Resistant Animals

(2008) David Patsouris et al.   Cell Metabolism