HERV-K activation is strictly required to sustain CD133+ melanoma cells with stemness features

CTRL+INSERT: retrotransposons and their contribution to regulation and innovation of the transcriptome

(2016) Jonathan Göke et al.   EMBO REPORTS

Prognostic significance of stem cell marker CD133 determined by promoter methylation but not by immunohistochemical expression in malignant gliomas

(2016) Xing Wu et al.   JOURNAL OF NEURO-ONCOLOGY

CD10-Equipped Melanoma Cells Acquire Highly Potent Tumorigenic Activity: A Plausible Explanation of Their Significance for a Poor Prognosis

(2016) Junna Oba et al.   PLoS One

Activation of HERV-K Env protein is essential for tumorigenesis and metastasis of breast cancer cells

(2016) Fuling Zhou et al.   Oncotarget

The Reverse Transcriptase Encoded by LINE-1 Retrotransposons in the Genesis, Progression, and Therapy of Cancer

(2016) Ilaria Sciamanna et al.   Frontiers in Chemistry

Abstract 4224: CD133 knockdown sensitizes melanoma to kinase inhibitors

(2015) Maryam AbdusSamad et al.   CANCER RESEARCH

Retrotransposons shape species-specific embryonic stem cell gene expression

(2015) Luisa Robbez-Masson et al.   Retrovirology

Transcriptional Activity of Human Endogenous Retroviruses in Human Peripheral Blood Mononuclear Cells

(2015) Emanuela Balestrieri et al.   Biomed Research International

Critical role of STAT3 in melanoma metastasis through anoikis resistance

(2015) Neel M. Fofaria et al.   Oncotarget

Regulatory roles of LINE-1-encoded reverse transcriptase in cancer onset and progression

(2015) Ilaria Sciamanna et al.   Oncotarget

Human endogenous retrovirus K and cancer: Innocent bystander or tumorigenic accomplice?

(2014) Ronan F. Downey et al.   INTERNATIONAL JOURNAL OF CANCER

Tackling the cancer stem cells — what challenges do they pose?

(2014) Diwakar R. Pattabiraman et al.   NATURE REVIEWS DRUG DISCOVERY

Are human endogenous retroviruses pathogenic? An approach to testing the hypothesis

(2013) George R. Young et al.   BIOESSAYS

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(2013) Luca Cegolon et al.   BMC CANCER

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(2013) Rüdiger M Zimmerer et al.   Cancer Cell International

Identification and analysis of CD133+ melanoma stem-like cells conferring resistance to taxol: An insight into the mechanisms of their resistance and response

(2013) Abdelouahid El-Khattouti et al.   CANCER LETTERS

Transcriptional Profiling of Human Endogenous Retrovirus Group HERV-K(HML-2) Loci in Melanoma

(2013) Katja Schmitt et al.   Genome Biology and Evolution

Targeting RAS/RAF/MEK/ERK signaling in metastatic melanoma

(2013) Ao-Xue Wang et al.   IUBMB LIFE

'There and back again': revisiting the pathophysiological roles of human endogenous retroviruses in the post-genomic era

(2013) G. Magiorkinis et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

The Human Melanoma Side Population Displays Molecular and Functional Characteristics of Enriched Chemoresistance and Tumorigenesis

(2013) Jasper Wouters et al.   PLoS One

Human endogenous retrovirus K (HML-2) RNA and protein expression is a marker for human embryonic and induced pluripotent stem cells

(2013) Nina V Fuchs et al.   Retrovirology

Human endogenous retroviruses and ADHD

(2013) Emanuela Balestrieri et al.   WORLD JOURNAL OF BIOLOGICAL PSYCHIATRY

HERV-K(HML-2), the Best Preserved Family of HERVs: Endogenization, Expression, and Implications in Health and Disease

(2013) Oliver Hohn et al.   Frontiers in Oncology

The stem cell marker prominin-1/CD133 interacts with vascular endothelial growth factor and potentiates its action

(2012) Avner Adini et al.   ANGIOGENESIS

Testing the cancer stem cell hypothesis in melanoma: The clinics will tell

(2012) Olga Shakhova et al.   CANCER LETTERS

CD133+ Melanoma Subpopulations Contribute to Perivascular Niche Morphogenesis and Tumorigenicity through Vasculogenic Mimicry

(2012) C.-Y. Lai et al.   CANCER RESEARCH

HERVs Expression in Autism Spectrum Disorders

(2012) Emanuela Balestrieri et al.   PLoS One

Melanoma stem cells: not rare, but well done

(2011) Sasha D Girouard et al.   LABORATORY INVESTIGATION

Retrotransposon-Encoded Reverse Transcriptase in the Genesis, Progression and Cellular Plasticity of Human Cancer

(2011) Paola Sinibaldi-Vallebona et al.   Cancers

Regulation of human endogenous retrovirus-K expression in melanomas by CpG methylation

(2010) Sven Stengel et al.   GENES CHROMOSOMES & CANCER

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(2010) Natasha Y. Frank et al.   JOURNAL OF CLINICAL INVESTIGATION

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(2010) Keith S. Hoek et al.   Pigment Cell & Melanoma Research

HLA and melanoma: multiple alterations in HLA class I and II expression in human melanoma cell lines from ESTDAB cell bank

(2009) Rosa Mendez et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

The activation of human endogenous retrovirus K (HERV-K) is implicated in melanoma cell malignant transformation

(2009) A. Serafino et al.   EXPERIMENTAL CELL RESEARCH

DNA hypomethylation in cancer cells

(2009) Melanie Ehrlich   Epigenomics

ICAM-1 Has a Critical Role in the Regulation of Metastatic Melanoma Tumor Susceptibility to CTL Lysis by Interfering with PI3K/AKT Pathway

(2008) A. Hamai et al.   CANCER RESEARCH

Epigenetic regulation of CD133 and tumorigenicity of CD133+ ovarian cancer cells

(2008) T Baba et al.   ONCOGENE

The Stem Cell-Associated Antigen CD133 (Prominin-1) Is a Molecular Therapeutic Target for Metastatic Melanoma

(2008) Germana Rappa et al.   STEM CELLS