Rosmarinic acid down-regulates NO and PGE2 expression via MAPK pathway in rat chondrocytes

Production of rosmarinic acid and salvianolic acid B from callus culture of Salvia miltiorrhiza with cytotoxicity towards acute lymphoblastic leukemia cells

(2016) Ching-Fen Wu et al.   FOOD CHEMISTRY

Rosmarinic acid is a homoserine lactone mimic produced by plants that activates a bacterial quorum-sensing regulator

(2016) Andrés Corral-Lugo et al.   Science Signaling

Rosmarinic acid is a homoserine lactone mimic produced by plants that activates a bacterial quorum-sensing regulator

(2016) Andrés Corral-Lugo et al.   Science Signaling

The novel adipokine progranulin counteracts IL-1 and TLR4-driven inflammatory response in human and murine chondrocytes via TNFR1

(2016) Vanessa Abella et al.   Scientific Reports

Inflammatory biomarkers in osteoarthritis

(2015) H.N. Daghestani et al.   OSTEOARTHRITIS AND CARTILAGE

Anti-inflammatory Effect of Rosmarinic Acid and an Extract ofRosmarinus officinalisin Rat Models of Local and Systemic Inflammation

(2014) Joao Rocha et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

High-Rosmarinic Acid Spearmint Tea in the Management of Knee Osteoarthritis Symptoms

(2014) A. Erin Connelly et al.   JOURNAL OF MEDICINAL FOOD

Emerging regulators of the inflammatory process in osteoarthritis

(2014) Ru Liu-Bryan et al.   Nature Reviews Rheumatology

Sulforaphane Represses Matrix-Degrading Proteases and Protects Cartilage From Destruction In Vitro and In Vivo

(2013) Rose K. Davidson et al.   ARTHRITIS AND RHEUMATISM

The NF-κB signalling pathway in osteoarthritis

(2013) Stella Rigoglou et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Salubrinal reduces expression and activity of MMP13 in chondrocytes

(2013) K. Hamamura et al.   OSTEOARTHRITIS AND CARTILAGE

The Role of Changes in Extracellular Matrix of Cartilage in the Presence of Inflammation on the Pathology of Osteoarthritis

(2013) Maricela Maldonado et al.   Biomed Research International

Morin exerts antiosteoarthritic properties: an in vitro and in vivo study

(2012) Wei-Ping Chen et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

In vivo reduction or blockade of interleukin-1β in primary osteoarthritis influences expression of mediators implicated in pathogenesis

(2012) K.S. Santangelo et al.   OSTEOARTHRITIS AND CARTILAGE

Proteases involved in cartilage matrix degradation in osteoarthritis

(2011) Linda Troeberg et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

New Hope for the Treatment of Osteoarthritis Through Selective Inhibition of MMP-13

(2011) N.-G. Li et al.   CURRENT MEDICINAL CHEMISTRY

Oral rosmarinic acid-enhanced Mentha spicata modulates synovial fluid biomarkers of inflammation in horses challenged with intra-articular LPS

(2011) W. PEARSON et al.   JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS

Rosmarinic Acid, Active Component of Dansam-Eum Attenuates Ototoxicity of Cochlear Hair Cells through Blockage of Caspase-1 Activity

(2011) Hyun-Ja Jeong et al.   PLoS One

NF-κB Signaling: Multiple Angles to Target OA

(2010) Kenneth B. Marcu et al.   CURRENT DRUG TARGETS

Rosmarinus officinalis polyphenols activate cholinergic activities in PC12 cells through phosphorylation of ERK1/2

(2010) Abdelfatteh El Omri et al.   JOURNAL OF ETHNOPHARMACOLOGY

LXR modulation blocks prostaglandin E2 production and matrix degradation in cartilage and alleviates pain in a rat osteoarthritis model

(2010) Ning Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rosmarinic acid sensitizes cell death through suppression of TNF-α-induced NF-κB activation and ROS generation in human leukemia U937 cells

(2009) Dong-Oh Moon et al.   CANCER LETTERS

Rosmarinic Acid in Prunella vulgaris Ethanol Extract Inhibits Lipopolysaccharide-Induced Prostaglandin E2 and Nitric Oxide in RAW 264.7 Mouse Macrophages

(2009) Nan Huang et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

MAPKs are essential upstream signaling pathways in proteolytic cartilage degradation – divergence in pathways leading to aggrecanase and MMP-mediated articular cartilage degradation

(2009) B.-C. Sondergaard et al.   OSTEOARTHRITIS AND CARTILAGE