PTK7 localization and protein stability is affected by canonical Wnt ligands

Delamination of neural crest cells requires transient and reversible Wnt inhibition mediated by Dact1/2

(2016) M. Angeles Rabadán et al.   DEVELOPMENT

Protein tyrosine kinase 7 is essential for tubular morphogenesis of the Wolffian duct

(2016) Bingfang Xu et al.   DEVELOPMENTAL BIOLOGY

Controlled levels of canonical Wnt signaling are required for neural crest migration

(2016) Ewa Maj et al.   DEVELOPMENTAL BIOLOGY

Ptk7 and Mcc, Unfancied Components in Non-Canonical Wnt Signaling and Cancer

(2016) Norris Dunn et al.   Cancers

Wnt-Frizzled/Planar Cell Polarity Signaling: Cellular Orientation by Facing the Wind (Wnt)

(2015) Yingzi Yang et al.   Annual Review of Cell and Developmental Biology

The PTK7 and ROR2 Protein Receptors Interact in the Vertebrate WNT/Planar Cell Polarity (PCP) Pathway

(2015) Sébastien Martinez et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A PTK7/Ror2 Co-Receptor Complex Affects Xenopus Neural Crest Migration

(2015) Martina Podleschny et al.   PLoS One

Distinct Apical and Basolateral Mechanisms Drive Planar Cell Polarity-Dependent Convergent Extension of the Mouse Neural Plate

(2014) Margot Williams et al.   DEVELOPMENTAL CELL

Live Imaging of Xwnt5A-ROR2 Complexes

(2014) Veronika Wallkamm et al.   PLoS One

The PTK7-Related Transmembrane Proteins Off-track and Off-track 2 Are Co-receptors for Drosophila Wnt2 Required for Male Fertility

(2014) Karen Linnemannstöns et al.   PLoS Genetics

The role of the non-canonical Wnt–planar cell polarity pathway in neural crest migration

(2013) Roberto Mayor et al.   BIOCHEMICAL JOURNAL

PTK7 modulates Wnt signaling activity via LRP6

(2013) N. Bin-Nun et al.   DEVELOPMENT

Ptk7 promotes non-canonical Wnt/PCP-mediated morphogenesis and inhibits Wnt/ -catenin-dependent cell fate decisions during vertebrate development

(2013) M. Hayes et al.   DEVELOPMENT

Caveolae as plasma membrane sensors, protectors and organizers

(2013) Robert G. Parton et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The many roles of PTK7: A versatile regulator of cell–cell communication

(2012) Hanna Peradziryi et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Suppression of Bmp4 signaling by the zinc-finger repressors Osr1 and Osr2 is required for Wnt/ -catenin-mediated lung specification in Xenopus

(2012) S. A. Rankin et al.   DEVELOPMENT

Live imaging of active fluorophore labelled Wnt proteins

(2012) Tatjana Holzer et al.   FEBS LETTERS

The Wnt Coreceptor Ryk Regulates Wnt/Planar Cell Polarity by Modulating the Degradation of the Core Planar Cell Polarity Component Vangl2

(2012) Philipp Andre et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Caveolin targeting to late endosome/lysosomal membranes is induced by perturbations of lysosomal pH and cholesterol content

(2012) Dorothy I. Mundy et al.   MOLECULAR BIOLOGY OF THE CELL

The complex world of WNT receptor signalling

(2012) Christof Niehrs   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Frizzled and LRP5/6 Receptors for Wnt/ -Catenin Signaling

(2012) B. T. MacDonald et al.   Cold Spring Harbor Perspectives in Biology

Planar Cell Polarity and the Developmental Control of Cell Behavior in Vertebrate Embryos

(2011) John B. Wallingford   Annual Review of Cell and Developmental Biology

RACK1 is a novel interaction partner of PTK7 that is required for neural tube closure

(2011) Peter Wehner et al.   DEVELOPMENT

Wnt Signaling Gradients Establish Planar Cell Polarity by Inducing Vangl2 Phosphorylation through Ror2

(2011) Bo Gao et al.   DEVELOPMENTAL CELL

PTK7/Otk interacts with Wnts and inhibits canonical Wnt signalling

(2011) Hanna Peradziryi et al.   EMBO JOURNAL

The novel mouse mutant, chuzhoi, has disruption of Ptk7 protein and exhibits defects in neural tube, heart and lung development and abnormal planar cell polarity in the ear

(2010) Anju Paudyal et al.   BMC DEVELOPMENTAL BIOLOGY

Quantifying colocalization by correlation: The Pearson correlation coefficient is superior to the Mander's overlap coefficient

(2010) Jeremy Adler et al.   CYTOMETRY PART A

An ATF2-based luciferase reporter to monitor non-canonical Wnt signaling in xenopus embryos

(2010) Bisei Ohkawara et al.   DEVELOPMENTAL DYNAMICS

Protein tyrosine kinase 7 has a conserved role in Wnt/β-catenin canonical signalling

(2010) Francesca Puppo et al.   EMBO REPORTS

PTK7 is essential for polarized cell motility and convergent extension during mouse gastrulation

(2009) W. W. Yen et al.   DEVELOPMENT

Wnt/β-Catenin Signaling: Components, Mechanisms, and Diseases

(2009) Bryan T. MacDonald et al.   DEVELOPMENTAL CELL

Planar Cell Polarity Signaling: The Developing Cell's Compass

(2009) E. K. Vladar et al.   Cold Spring Harbor Perspectives in Biology

Planar Cell Polarity Signaling: From Fly Development to Human Disease

(2008) Matias Simons et al.   Annual Review of Genetics

PTK7 recruits dsh to regulate neural crest migration

(2008) I. Shnitsar et al.   DEVELOPMENT

Receptor Tyrosine Kinase Ror2 Mediates Wnt5a-induced Polarized Cell Migration by Activating c-Jun N-terminal Kinase via Actin-binding Protein Filamin A

(2008) Akira Nomachi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Alternative Wnt Signaling Is Initiated by Distinct Receptors

(2008) R. van Amerongen et al.   Science Signaling