The PTK7 and ROR2 Protein Receptors Interact in the Vertebrate WNT/Planar Cell Polarity (PCP) Pathway

Insight into planar cell polarity

(2014) Michael Sebbagh et al.   EXPERIMENTAL CELL RESEARCH

The PTK7-Related Transmembrane Proteins Off-track and Off-track 2 Are Co-receptors for Drosophila Wnt2 Required for Male Fertility

(2014) Karen Linnemannstöns et al.   PLoS Genetics

PTK7 modulates Wnt signaling activity via LRP6

(2013) N. Bin-Nun et al.   DEVELOPMENT

Ptk7 promotes non-canonical Wnt/PCP-mediated morphogenesis and inhibits Wnt/ -catenin-dependent cell fate decisions during vertebrate development

(2013) M. Hayes et al.   DEVELOPMENT

The Cytosolic Domain of Protein-tyrosine Kinase 7 (PTK7), Generated from Sequential Cleavage by a Disintegrin and Metalloprotease 17 (ADAM17) and γ-Secretase, Enhances Cell Proliferation and Migration in Colon Cancer Cells

(2012) Hye-Won Na et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Insights into Ectodomain Shedding and Processing of Protein-tyrosine Pseudokinase 7 (PTK7)

(2012) Vladislav S. Golubkov et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Planar Cell Polarity and the Developmental Control of Cell Behavior in Vertebrate Embryos

(2011) John B. Wallingford   Annual Review of Cell and Developmental Biology

Flt-1 regulates vascular endothelial cell migration via a protein tyrosine kinase-7-dependent pathway

(2011) H. K. Lee et al.   BLOOD

PTK7: A cell polarity receptor with multiple facets

(2011) Anne-Catherine Lhoumeau et al.   CELL CYCLE

PTK7/Otk interacts with Wnts and inhibits canonical Wnt signalling

(2011) Hanna Peradziryi et al.   EMBO JOURNAL

Potential Relation of Aberrant Proteolysis of Human Protein Tyrosine Kinase 7 (PTK7)chuzhoiby Membrane Type 1 Matrix Metalloproteinase (MT1-MMP) to Congenital Defects

(2011) Vladislav S. Golubkov et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The novel mouse mutant, chuzhoi, has disruption of Ptk7 protein and exhibits defects in neural tube, heart and lung development and abnormal planar cell polarity in the ear

(2010) Anju Paudyal et al.   BMC DEVELOPMENTAL BIOLOGY

Distinct Xenopus Nodal ligands sequentially induce mesendoderm and control gastrulation movements in parallel to the Wnt/PCP pathway

(2010) G. Luxardi et al.   DEVELOPMENT

Protein tyrosine kinase 7 has a conserved role in Wnt/β-catenin canonical signalling

(2010) Francesca Puppo et al.   EMBO REPORTS

The Wnt/Planar Cell Polarity Protein-tyrosine Kinase-7 (PTK7) Is a Highly Efficient Proteolytic Target of Membrane Type-1 Matrix Metalloproteinase

(2010) Vladislav S. Golubkov et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ror-family receptor tyrosine kinases in noncanonical Wnt signaling: Their implications in developmental morphogenesis and human diseases

(2009) Yasuhiro Minami et al.   DEVELOPMENTAL DYNAMICS

Wnt signaling pathways meet Rho GTPases

(2009) K. Schlessinger et al.   GENES & DEVELOPMENT

Proximal events in Wnt signal transduction

(2009) Stephane Angers et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

BMP inhibition initiates neural induction via FGF signaling and Zic genes

(2009) L. Marchal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Planar Cell Polarity Signaling: From Fly Development to Human Disease

(2008) Matias Simons et al.   Annual Review of Genetics

The planar polarity pathway

(2008) David Strutt   CURRENT BIOLOGY

PTK7 recruits dsh to regulate neural crest migration

(2008) I. Shnitsar et al.   DEVELOPMENT

Receptor Tyrosine Kinase Ror2 Mediates Wnt5a-induced Polarized Cell Migration by Activating c-Jun N-terminal Kinase via Actin-binding Protein Filamin A

(2008) Akira Nomachi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY