Emerging roles of MICAL family proteins – from actin oxidation to membrane trafficking during cytokinesis

Oxidation of F-actin controls the terminal steps of cytokinesis

(2017) Stéphane Frémont et al.   Nature Communications

Properties and catalytic activities of MICAL1, the flavoenzyme involved in cytoskeleton dynamics, and modulation by its CH, LIM and C-terminal domains

(2016) Teresa Vitali et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

MICAL1 controls cell invasive phenotype via regulating oxidative stress in breast cancer cells

(2016) Wenjie Deng et al.   BMC CANCER

Rab35 GTPase Triggers Switch-like Recruitment of the Lowe Syndrome Lipid Phosphatase OCRL on Newborn Endosomes

(2016) Clothilde Cauvin et al.   CURRENT BIOLOGY

Actin filaments-A target for redox regulation

(2016) Carlos Wilson et al.   Cytoskeleton

EHD3 Protein Is Required for Tubular Recycling Endosome Stabilization, and an Asparagine-Glutamic Acid Residue Pair within Its Eps15 Homology (EH) Domain Dictates Its Selective Binding to NPF Peptides

(2016) Kriti Bahl et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MICAL3 Flavoprotein Monooxygenase Forms a Complex with Centralspindlin and Regulates Cytokinesis

(2016) Qingyang Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rab35 Functions in Axon Elongation Are Regulated by P53-Related Protein Kinase in a Mechanism That Involves Rab35 Protein Degradation and the Microtubule-Associated Protein 1B

(2016) D. Villarroel-Campos et al.   JOURNAL OF NEUROSCIENCE

A complex of Rab13 with MICAL-L2 and α-actinin-4 is essential for insulin-dependent GLUT4 exocytosis

(2016) Yi Sun et al.   MOLECULAR BIOLOGY OF THE CELL

Conformational plasticity of JRAB/MICAL-L2 provides “law and order” in collective cell migration

(2016) Ayuko Sakane et al.   MOLECULAR BIOLOGY OF THE CELL

MICAL-like Regulates Fasciclin II Membrane Cycling and Synaptic Development

(2016) Minyeop Nahm et al.   MOLECULES AND CELLS

F-actin dismantling through a redox-driven synergy between Mical and cofilin

(2016) Elena E. Grintsevich et al.   NATURE CELL BIOLOGY

Rab35 GTPase: A Central Regulator of Phosphoinositides and F-actin in Endocytic Recycling and Beyond

(2016) Kerstin Klinkert et al.   TRAFFIC

Rab35 GTPase couples cell division with initiation of epithelial apico-basal polarity and lumen opening

(2016) Kerstin Klinkert et al.   Nature Communications

bMERB domains are bivalent Rab8 family effectors evolved by gene duplication

(2016) Amrita Rai et al.   eLife

Modulation of MICAL Monooxygenase Activity by its Calponin Homology Domain: Structural and Mechanistic Insights

(2016) Saif S. Alqassim et al.   Scientific Reports

Resolving new ultrastructural features of cytokinetic abscission with soft-X-ray cryo-tomography

(2016) Shachar Sherman et al.   Scientific Reports

Phosphoinositides: Lipids with informative heads and mastermind functions in cell division

(2015) Clothilde Cauvin et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Silencing of MICAL-L2 suppresses malignancy of ovarian cancer by inducing mesenchymal–epithelial transition

(2015) Lin-Yan Zhu et al.   CANCER LETTERS

Semaphorin 3a transfection into the left stellate ganglion reduces susceptibility to ventricular arrhythmias after myocardial infarction in rats

(2015) Ling-Chao Yang et al.   EUROPACE

DENND2B activates Rab13 at the leading edge of migrating cells and promotes metastatic behavior

(2015) Maria S. Ioannou et al.   JOURNAL OF CELL BIOLOGY

The HIV-1 protein Vpr impairs phagosome maturation by controlling microtubule-dependent trafficking

(2015) Audrey Dumas et al.   JOURNAL OF CELL BIOLOGY

MICAL2 is a novel human cancer gene controlling mesenchymal to epithelial transition involved in cancer growth and invasion

(2015) Sara Mariotti et al.   Oncotarget

The Ciliopathy Protein CC2D2A Associates with NINL and Functions in RAB8-MICAL3-Regulated Vesicle Trafficking

(2015) Ruxandra Bachmann-Gagescu et al.   PLoS Genetics

Sema6A and Mical1 control cell growth and survival of BRAFV600E human melanoma cells

(2015) Rossella Loria et al.   Oncotarget

Redox Modification of Nuclear Actin by MICAL-2 Regulates SRF Signaling

(2014) Mark R. Lundquist et al.   CELL

Cytokinetic Abscission: Molecular Mechanisms and Temporal Control

(2014) Beata Mierzwa et al.   DEVELOPMENTAL CELL

Semaphorin3a Promotes Advanced Diabetic Nephropathy

(2014) Pardeep K. Aggarwal et al.   DIABETES

Engulfment of the midbody remnant after cytokinesis in mammalian cells

(2014) E. F. Crowell et al.   JOURNAL OF CELL SCIENCE

Novel Functions for the Endocytic Regulatory Proteins MICAL-L1 and EHD1 in Mitosis

(2014) James B. Reinecke et al.   TRAFFIC

The intracellular redox protein MICAL-1 regulates the development of hippocampal mossy fibre connections

(2014) Eljo Y. Van Battum et al.   Nature Communications

Rab35 promotes the recruitment of Rab8, Rab13 and Rab36 to recycling endosomes through MICAL-L1 during neurite outgrowth

(2014) H. Kobayashi et al.   Biology Open

MICAL-Family Proteins: Complex Regulators of the Actin Cytoskeleton

(2013) Sai Srinivas Panapakkam Giridharan et al.   ANTIOXIDANTS & REDOX SIGNALING

Junctional Rab13-binding protein (JRAB) regulates cell spreading via filamins

(2013) Ayuko Sakane et al.   GENES TO CELLS

Rab35 establishes the EHD1-association site by coordinating two distinct effectors during neurite outgrowth

(2013) H. Kobayashi et al.   JOURNAL OF CELL SCIENCE

MsrB1 and MICALs Regulate Actin Assembly and Macrophage Function via Reversible Stereoselective Methionine Oxidation

(2013) Byung Cheon Lee et al.   MOLECULAR CELL

SelR reverses Mical-mediated oxidation of actin to regulate F-actin dynamics

(2013) Ruei-Jiun Hung et al.   NATURE CELL BIOLOGY

ESCRT-III Assembly and Cytokinetic Abscission Are Induced by Tension Release in the Intercellular Bridge

(2013) J. Lafaurie-Janvore et al.   SCIENCE

Endocytic transport and cytokinesis: from regulation of the cytoskeleton to midbody inheritance

(2013) John A. Schiel et al.   TRENDS IN CELL BIOLOGY

Cytokinesis in Animal Cells

(2012) Rebecca A. Green et al.   Annual Review of Cell and Developmental Biology

Computational Model of Cytokinetic Abscission Driven by ESCRT-III Polymerization and Remodeling

(2012) Natalie Elia et al.   BIOPHYSICAL JOURNAL

An ARF6/Rab35 GTPase Cascade for Endocytic Recycling and Successful Cytokinesis

(2012) Laurent Chesneau et al.   CURRENT BIOLOGY

Membrane dynamics during cytokinesis

(2012) John A Schiel et al.   CURRENT OPINION IN CELL BIOLOGY

Rab13 Small G Protein and Junctional Rab13-binding Protein (JRAB) Orchestrate Actin Cytoskeletal Organization during Epithelial Junctional Development

(2012) Ayuko Sakane et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rab35 regulates Arf6 activity through centaurin- 2 (ACAP2) during neurite outgrowth

(2012) H. Kobayashi et al.   JOURNAL OF CELL SCIENCE

Differential regulation of actin microfilaments by human MICAL proteins

(2012) S. S. P. Giridharan et al.   JOURNAL OF CELL SCIENCE

FIP3-endosome-dependent formation of the secondary ingression mediates ESCRT-III recruitment during cytokinesis

(2012) John A. Schiel et al.   NATURE CELL BIOLOGY

Molecular control of animal cell cytokinesis

(2012) Juan Pablo Fededa et al.   NATURE CELL BIOLOGY

Rab6, Rab8, and MICAL3 Cooperate in Controlling Docking and Fusion of Exocytotic Carriers

(2011) Ilya Grigoriev et al.   CURRENT BIOLOGY

Linking cytoplasmic dynein and transport of Rab8 vesicles to the midbody during cytokinesis by the doublecortin domain-containing 5 protein

(2011) A. Kaplan et al.   JOURNAL OF CELL SCIENCE

Endocytic membrane fusion and buckling-induced microtubule severing mediate cell abscission

(2011) J. A. Schiel et al.   JOURNAL OF CELL SCIENCE

Rab35 regulates phagosome formation through recruitment of ACAP2 in macrophages during Fc R-mediated phagocytosis

(2011) Y. Egami et al.   JOURNAL OF CELL SCIENCE

MICAL-1 Is a Negative Regulator of MST-NDR Kinase Signaling and Apoptosis

(2011) Y. Zhou et al.   MOLECULAR AND CELLULAR BIOLOGY

MICAL-like1 mediates epidermal growth factor receptor endocytosis

(2011) Nancy Abou-Zeid et al.   MOLECULAR BIOLOGY OF THE CELL

Rab35 GTPase and OCRL phosphatase remodel lipids and F-actin for successful cytokinesis

(2011) Daphné Dambournet et al.   NATURE CELL BIOLOGY

Dynamics of endosomal sorting complex required for transport (ESCRT) machinery during cytokinesis and its role in abscission

(2011) N. Elia et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Direct Redox Regulation of F-Actin Assembly and Disassembly by Mical

(2011) R.-J. Hung et al.   SCIENCE

Cortical Constriction During Abscission Involves Helices of ESCRT-III-Dependent Filaments

(2011) J. Guizetti et al.   SCIENCE

Thioredoxin Mediates Oxidation-Dependent Phosphorylation of CRMP2 and Growth Cone Collapse

(2011) A. Morinaka et al.   Science Signaling

Expression pattern of Mical-1 in the temporal neocortex of patients with intractable temporal epilepsy and pilocarpine-induced rat model

(2011) Jing Luo et al.   SYNAPSE

MICAL-L1 is a Tubular Endosomal Membrane Hub that Connects Rab35 and Arf6 With Rab8a

(2011) Juliati Rahajeng et al.   TRAFFIC

Cytokinesis and cancer

(2010) Antonia P. Sagona et al.   FEBS LETTERS

Mical links semaphorins to F-actin disassembly

(2010) Ruei-Jiun Hung et al.   NATURE

Quantitative evaluation of tryptophan oxidation in actin and troponin I from skeletal muscles using a rat model of acute oxidative stress

(2010) Maria Fedorova et al.   PROTEOMICS

MICAL-L1 Links EHD1 to Tubular Recycling Endosomes and Regulates Receptor Recycling

(2009) Mahak Sharma et al.   MOLECULAR BIOLOGY OF THE CELL

A genetic pathway composed of Sox14 and Mical governs severing of dendrites during pruning

(2009) Daniel Kirilly et al.   NATURE NEUROSCIENCE

Rab GTPases as coordinators of vesicle traffic

(2009) Harald Stenmark   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Endocytic traffic in animal cell cytokinesis

(2008) Guillaume Montagnac et al.   CURRENT OPINION IN CELL BIOLOGY

Rab35 and Its GAP EPI64C in T Cells Regulate Receptor Recycling and Immunological Synapse Formation

(2008) Genaro Patino-Lopez et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Release of MICAL Autoinhibition by Semaphorin-Plexin Signaling Promotes Interaction with Collapsin Response Mediator Protein

(2008) E. F. Schmidt et al.   JOURNAL OF NEUROSCIENCE

Large Scale Screening for Novel Rab Effectors Reveals Unexpected Broad Rab Binding Specificity

(2008) Mitsunori Fukuda et al.   MOLECULAR & CELLULAR PROTEOMICS

Involvement of Actinin-4 in the Recruitment of JRAB/MICAL-L2 to Cell-Cell Junctions and the Formation of Functional Tight Junctions

(2008) H. Nakatsuji et al.   MOLECULAR AND CELLULAR BIOLOGY

Structural basis for midbody targeting of spastin by the ESCRT-III protein CHMP1B

(2008) Dong Yang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Spastin Couples Microtubule Severing to Membrane Traffic in Completion of Cytokinesis and Secretion

(2008) James W. Connell et al.   TRAFFIC

The Interaction of JRAB/MICAL-L2 with Rab8 and Rab13 Coordinates the Assembly of Tight Junctions and Adherens Junctions

(2007) Rie Yamamura et al.   MOLECULAR BIOLOGY OF THE CELL