Rab35 GTPase: A Central Regulator of Phosphoinositides and F-actin in Endocytic Recycling and Beyond

Regulation of T Cell Receptor Signaling by DENND1B in T H 2 Cells and Allergic Disease

(2016) Chiao-Wen Yang et al.   CELL

Rab35 GTPase Triggers Switch-like Recruitment of the Lowe Syndrome Lipid Phosphatase OCRL on Newborn Endosomes

(2016) Clothilde Cauvin et al.   CURRENT BIOLOGY

Rab3A, Rab27A, and Rab35 regulate different events during mouse oocyte meiotic maturation and activation

(2016) H. H. Wang et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Regulation of podocalyxin trafficking by Rab small GTPases in 2D and 3D epithelial cell cultures

(2016) Paulina S. Mrozowska et al.   JOURNAL OF CELL BIOLOGY

Rab35 GTPase couples cell division with initiation of epithelial apico-basal polarity and lumen opening

(2016) Kerstin Klinkert et al.   Nature Communications

Phosphoinositides: Lipids with informative heads and mastermind functions in cell division

(2015) Clothilde Cauvin et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Phosphorylation-dependent Regulation of Connecdenn/DENND1 Guanine Nucleotide Exchange Factors

(2015) Gopinath Kulasekaran et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure-Function Analyses of the Small GTPase Rab35 and Its Effector Protein Centaurin-β2/ACAP2 during Neurite Outgrowth of PC12 Cells

(2015) Kan Etoh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of an oncogenic RAB protein

(2015) D. B. Wheeler et al.   SCIENCE

Sorting of Clathrin-Independent Cargo Proteins Depends on Rab35 Delivered by Clathrin-Mediated Endocytosis

(2015) Dipannita Dutta et al.   TRAFFIC

MicroRNA-720 promotes in vitro cell migration by targeting Rab35 expression in cervical cancer cells

(2015) Yunlan Tang et al.   Cell and Bioscience

Intracellular Uropathogenic E. coli Exploits Host Rab35 for Iron Acquisition and Survival within Urinary Bladder Cells

(2015) Neha Dikshit et al.   PLoS Pathogens

Activation-Inactivation Cycling of Rab35 and ARF6 Is Required for Phagocytosis of Zymosan in RAW264 Macrophages

(2015) Youhei Egami et al.   Journal of Immunology Research

Intercellular Transfer of GPRC5B via Exosomes Drives HGF-Mediated Outward Growth

(2014) Sang-Ho Kwon et al.   CURRENT BIOLOGY

Cytokinetic Abscission: Molecular Mechanisms and Temporal Control

(2014) Beata Mierzwa et al.   DEVELOPMENTAL CELL

CLIC4 regulates cell adhesion and  1 integrin trafficking

(2014) E. Argenzio et al.   JOURNAL OF CELL SCIENCE

Rab35, acting through ACAP2 switching off Arf6, negatively regulates oligodendrocyte differentiation and myelination

(2014) Yuki Miyamoto et al.   MOLECULAR BIOLOGY OF THE CELL

The role of the hypervariable C-terminal domain in Rab GTPases membrane targeting

(2014) F. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Cellular and Physiological Functions of the Lowe Syndrome Protein OCRL1

(2014) Zenobia B. Mehta et al.   TRAFFIC

Diversity and plasticity in Rab GTPase nucleotide release mechanism has consequences for Rab activation and inactivation

(2014) Lars Langemeyer et al.   eLife

Rab35 promotes the recruitment of Rab8, Rab13 and Rab36 to recycling endosomes through MICAL-L1 during neurite outgrowth

(2014) H. Kobayashi et al.   Biology Open

MICAL-Family Proteins: Complex Regulators of the Actin Cytoskeleton

(2013) Sai Srinivas Panapakkam Giridharan et al.   ANTIOXIDANTS & REDOX SIGNALING

Rab35 is required for Wnt5a/Dvl2-induced Rac1 activation and cell migration in MCF-7 breast cancer cells

(2013) Yichao Zhu et al.   CELLULAR SIGNALLING

Mechanism of Rab1b deactivation by the Legionella pneumophila GAP LepB

(2013) Emerich Mihai Gazdag et al.   EMBO REPORTS

ARH directs megalin to the endocytic recycling compartment to regulate its proteolysis and gene expression

(2013) Mehul Shah et al.   JOURNAL OF CELL BIOLOGY

Rab35 establishes the EHD1-association site by coordinating two distinct effectors during neurite outgrowth

(2013) H. Kobayashi et al.   JOURNAL OF CELL SCIENCE

The Folliculin Tumor Suppressor Is a GAP for the RagC/D GTPases That Signal Amino Acid Levels to mTORC1

(2013) Zhi-Yang Tsun et al.   MOLECULAR CELL

Membrane extraction of Rab proteins by GDP dissociation inhibitor characterized using attenuated total reflection infrared spectroscopy

(2013) K. Gavriljuk et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hijacking Multivesicular Bodies Enables Long-Term and Exosome-Mediated Long-Distance Action of Anthrax Toxin

(2013) Laurence Abrami et al.   Cell Reports

Untangling the evolution of Rab G proteins: implications of a comprehensive genomic analysis

(2012) Tobias H Klöpper et al.   BMC BIOLOGY

An ARF6/Rab35 GTPase Cascade for Endocytic Recycling and Successful Cytokinesis

(2012) Laurent Chesneau et al.   CURRENT BIOLOGY

Phosphoinositides and cytokinesis: The “PIP” of the iceberg

(2012) Arnaud Echard   Cytoskeleton

The NF-κB Signaling Protein Bcl10 Regulates Actin Dynamics by Controlling AP1 and OCRL-Bearing Vesicles

(2012) Sabrina Marion et al.   DEVELOPMENTAL CELL

Reversible phosphocholination of Rab proteins byLegionella pneumophilaeffector proteins

(2012) Philip R Goody et al.   EMBO JOURNAL

Phosphatidylinositol 5-Phosphatase Oculocerebrorenal Syndrome of Lowe Protein (OCRL) Controls Actin Dynamics during Early Steps ofListeria monocytogenesInfection

(2012) Andreas Kühbacher et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Interplay between Rab35 and Arf6 controls cargo recycling to coordinate cell adhesion and migration

(2012) P. D. Allaire et al.   JOURNAL OF CELL SCIENCE

Rab35 regulates Arf6 activity through centaurin- 2 (ACAP2) during neurite outgrowth

(2012) H. Kobayashi et al.   JOURNAL OF CELL SCIENCE

Rab35 regulates cadherin-mediated adherens junction formation and myoblast fusion

(2012) Sophie Charrasse et al.   MOLECULAR BIOLOGY OF THE CELL

Whacked and Rab35 polarize dynein-motor-complex-dependent seamless tube growth

(2012) Jodi Schottenfeld-Roames et al.   NATURE CELL BIOLOGY

TBC1D13 is a RAB35 Specific GAP that Plays an Important Role in GLUT4 Trafficking in Adipocytes

(2012) Jonathan R. Davey et al.   TRAFFIC

Inositol 5-phosphatases: insights from the Lowe syndrome protein OCRL

(2012) Michelle Pirruccello et al.   TRENDS IN BIOCHEMICAL SCIENCES

Crystal structure of folliculin reveals a hidDENN function in genetically inherited renal cancer

(2012) R. K. Nookala et al.   Open Biology

Discovery of Novel DENN Proteins: Implications for the Evolution of Eukaryotic Intracellular Membrane Structures and Human Disease

(2012) Dapeng Zhang et al.   Frontiers in Genetics

Loss of Skywalker Reveals Synaptic Endosomes as Sorting Stations for Synaptic Vesicle Proteins

(2011) Valerie Uytterhoeven et al.   CELL

Genome-wide Investigation of the Rab Binding Activity of RUN Domains: Development of a Novel Tool that Specifically Traps GTP-Rab35

(2011) Mitsunori Fukuda et al.   CELL STRUCTURE AND FUNCTION

Decoupling of Activation and Effector Binding Underlies ARF6 Priming of Fast Endocytic Recycling

(2011) Guillaume Montagnac et al.   CURRENT BIOLOGY

OCRL controls trafficking through early endosomes via PtdIns4,5P2-dependent regulation of endosomal actin

(2011) Mariella Vicinanza et al.   EMBO JOURNAL

DENN Domain Proteins: Regulators of Rab GTPases

(2011) Andrea L. Marat et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rab35 regulates phagosome formation through recruitment of ACAP2 in macrophages during Fc R-mediated phagocytosis

(2011) Y. Egami et al.   JOURNAL OF CELL SCIENCE

Connecdenn 3/DENND1C binds actin linking Rab35 activation to the actin cytoskeleton

(2011) Andrea L. Marat et al.   MOLECULAR BIOLOGY OF THE CELL

Modulation of Rab GTPase function by a protein phosphocholine transferase

(2011) Shaeri Mukherjee et al.   NATURE

Rab35 GTPase and OCRL phosphatase remodel lipids and F-actin for successful cytokinesis

(2011) Daphné Dambournet et al.   NATURE CELL BIOLOGY

Insights regarding guanine nucleotide exchange from the structure of a DENN-domain protein complexed with its Rab GTPase substrate

(2011) X. Wu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MICAL-L1 is a Tubular Endosomal Membrane Hub that Connects Rab35 and Arf6 With Rab8a

(2011) Juliati Rahajeng et al.   TRAFFIC

The Anaplasma phagocytophilum-occupied vacuole selectively recruits Rab-GTPases that are predominantly associated with recycling endosomes

(2010) Bernice Huang et al.   CELLULAR MICROBIOLOGY

Recycling of the Ca2+-activated K+Channel, KCa2.3, Is Dependent upon RME-1, Rab35/EPI64C, and an N-terminal Domain

(2010) Yajuan Gao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Connecdenn Family, Rab35 Guanine Nucleotide Exchange Factors Interfacing with the Clathrin Machinery

(2010) Andrea L. Marat et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Family-wide characterization of the DENN domain Rab GDP-GTP exchange factors

(2010) Shin-ichiro Yoshimura et al.   JOURNAL OF CELL BIOLOGY

Regulation of exosome secretion by Rab35 and its GTPase-activating proteins TBC1D10A–C

(2010) Chieh Hsu et al.   JOURNAL OF CELL BIOLOGY

Rab35 Mediates Transport of Cdc42 and Rac1 to the Plasma Membrane during Phagocytosis

(2010) J. Shim et al.   MOLECULAR AND CELLULAR BIOLOGY

The Connecdenn DENN Domain: A GEF for Rab35 Mediating Cargo-Specific Exit from Early Endosomes

(2010) Patrick D. Allaire et al.   MOLECULAR CELL

Comprehensive Screening for Novel Rab-Binding Proteins by GST Pull-Down Assay Using 60 Different Mammalian Rabs‡

(2010) Eiko Kanno et al.   TRAFFIC

Androgen-related expression of G-proteins in ovarian cancer

(2009) L A Sheach et al.   BRITISH JOURNAL OF CANCER

Rab35 regulates neurite outgrowth and cell shape

(2009) Julien Chevallier et al.   FEBS LETTERS

Rab35 - A vesicular traffic-regulating small GTPase with actin modulating roles

(2009) Christelle En Lin Chua et al.   FEBS LETTERS

Rab GTPases as coordinators of vesicle traffic

(2009) Harald Stenmark   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Pathways and mechanisms of endocytic recycling

(2009) Barth D. Grant et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Rab35 Controls Actin Bundling by Recruiting Fascin as an Effector Protein

(2009) J. Zhang et al.   SCIENCE

Regulation of endocytic recycling by C. elegans Rab35 and its regulator RME-4, a coated-pit protein

(2008) Miyuki Sato et al.   EMBO JOURNAL

Rab35 and Its GAP EPI64C in T Cells Regulate Receptor Recycling and Immunological Synapse Formation

(2008) Genaro Patino-Lopez et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Major Histocompatibility Complex Class II-Peptide Complexes Internalize Using a Clathrin- and Dynamin-independent Endocytosis Pathway

(2008) Even Walseng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY