Cardiolipin promotes electron transport between ubiquinone and complex I to rescuePINK1deficiency

Increased Ceramide in Brains with Alzheimer's and Other Neurodegenerative Diseases

(2018) Valery Filippov et al.   JOURNAL OF ALZHEIMERS DISEASE

Dual loss of succinate dehydrogenase (SDH) and complex I activity is necessary to recapitulate the metabolic phenotype of SDH mutant tumors

(2017) Doriane Lorendeau et al.   METABOLIC ENGINEERING

Breast Cancer-Derived Lung Metastases Show Increased Pyruvate Carboxylase-Dependent Anaplerosis

(2016) Stefan Christen et al.   Cell Reports

An automated shotgun lipidomics platform for high throughput, comprehensive, and quantitative analysis of blood plasma intact lipids

(2015) Michal A. Surma et al.   EUROPEAN JOURNAL OF LIPID SCIENCE AND TECHNOLOGY

LC/MS analysis of cardiolipins in substantia nigra and plasma of rotenone-treated rats: Implication for mitochondrial dysfunction in Parkinson's disease

(2015) Y. Y. Tyurina et al.   FREE RADICAL RESEARCH

Mitochondria: A crossroads for lipid metabolism defect in neurodegeneration with brain iron accumulation diseases

(2015) Manar Aoun et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Regulation of mitochondrial morphology and function by stearoylation of TFR1

(2015) Deniz Senyilmaz et al.   NATURE

Ceramides in Alzheimer’s Disease: Key Mediators of Neuronal Apoptosis Induced by Oxidative Stress and AβAccumulation

(2015) Maja Jazvinšćak Jembrek et al.   Oxidative Medicine and Cellular Longevity

M-CSF from Cancer Cells Induces Fatty Acid Synthase and PPARβ/δ Activation in Tumor Myeloid Cells, Leading to Tumor Progression

(2015) Jonghanne Park et al.   Cell Reports

Fatty Acid Synthase Cooperates with Glyoxalase 1 to Protect against Sugar Toxicity

(2015) Damien Garrido et al.   PLoS Genetics

MICOS coordinates with respiratory complexes and lipids to establish mitochondrial inner membrane architecture

(2015) Jonathan R Friedman et al.   eLife

Retromer-dependent neurotransmitter receptor trafficking to synapses is altered by the Parkinson's disease VPS35 mutation p.D620N

(2014) L. N. Munsie et al.   HUMAN MOLECULAR GENETICS

PINK1 Loss-of-Function Mutations Affect Mitochondrial Complex I Activity via NdufA10 Ubiquinone Uncoupling

(2014) V. A. Morais et al.   SCIENCE

The Complex I Subunit NDUFA10 Selectively Rescues Drosophila pink1 Mutants through a Mechanism Independent of Mitophagy

(2014) Joe H. Pogson et al.   PLoS Genetics

Mutations in the Intellectual Disability Gene Ube2a Cause Neuronal Dysfunction and Impair Parkin-Dependent Mitophagy

(2013) Dominik M. Haddad et al.   MOLECULAR CELL

Cardiolipin externalization to the outer mitochondrial membrane acts as an elimination signal for mitophagy in neuronal cells

(2013) Charleen T. Chu et al.   NATURE CELL BIOLOGY

Near-Infrared 808 nm Light Boosts Complex IV-Dependent Respiration and Rescues a Parkinson-Related pink1 Model

(2013) Melissa Vos et al.   PLoS One

Aconitase Causes Iron Toxicity in Drosophila pink1 Mutants

(2013) Giovanni Esposito et al.   PLoS Genetics

Phosphatase and Tensin Homolog (PTEN)-induced Putative Kinase 1 (PINK1)-dependent Ubiquitination of Endogenous Parkin Attenuates Mitophagy

(2012) Aleksandar Rakovic et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

LipidXplorer: A Software for Consensual Cross-Platform Lipidomics

(2012) Ronny Herzog et al.   PLoS One

Vitamin K2 Is a Mitochondrial Electron Carrier That Rescues Pink1 Deficiency

(2012) M. Vos et al.   SCIENCE

The Yeast Complex I Equivalent NADH Dehydrogenase Rescues pink1 Mutants

(2012) Sven Vilain et al.   PLoS Genetics

Cardiolipin Affects the Supramolecular Organization of ATP Synthase in Mitochondria

(2011) Devrim Acehan et al.   BIOPHYSICAL JOURNAL

Lanosterol induces mitochondrial uncoupling and protects dopaminergic neurons from cell death in a model for Parkinson's disease

(2011) L Lim et al.   CELL DEATH AND DIFFERENTIATION

Dopamine neurons derived from human ES cells efficiently engraft in animal models of Parkinson’s disease

(2011) Sonja Kriks et al.   NATURE

Membrane lipidome of an epithelial cell line

(2011) Julio L. Sampaio et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A novel informatics concept for high-throughput shotgun lipidomics based on the molecular fragmentation query language

(2011) Ronny Herzog et al.   GENOME BIOLOGY

Fatty Acid Synthase Polymorphisms, Tumor Expression, Body Mass Index, Prostate Cancer Risk, and Survival

(2010) Paul L. Nguyen et al.   JOURNAL OF CLINICAL ONCOLOGY

PINK1 Is Selectively Stabilized on Impaired Mitochondria to Activate Parkin

(2010) Derek P. Narendra et al.   PLOS BIOLOGY

Parkin-induced mitophagy in the pathogenesis of Parkinson disease

(2009) Derek Narendra et al.   Autophagy

Parkinson's disease mutations in PINK1 result in decreased Complex I activity and deficient synaptic function

(2009) Vanessa A. Morais et al.   EMBO Molecular Medicine

Differential effects of PINK1 nonsense and missense mutations on mitochondrial function and morphology

(2009) A. Grünewald et al.   EXPERIMENTAL NEUROLOGY

Global analysis of the yeast lipidome by quantitative shotgun mass spectrometry

(2009) C. S. Ejsing et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Integrating cybernetic modeling with pathway analysis provides a dynamic, systems-level description of metabolic control

(2008) Jamey D. Young et al.   BIOTECHNOLOGY AND BIOENGINEERING

Cohort Study of Fatty Acid Synthase Expression and Patient Survival in Colon Cancer

(2008) Shuji Ogino et al.   JOURNAL OF CLINICAL ONCOLOGY

Loss of cardiolipin in palmitate-treated GL15 glioblastoma cells favors cytochrome c release from mitochondria leading to apoptosis

(2008) Morena Buratta et al.   JOURNAL OF NEUROCHEMISTRY

Loss of PINK1 causes mitochondrial functional defects and increased sensitivity to oxidative stress

(2008) C. A. Gautier et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The PINK1/Parkin pathway regulates mitochondrial morphology

(2008) A. C. Poole et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA